Systematic Review of the Systemic Concentrations of Local Anaesthetic After Transversus Abdominis Plane Block and Rectus Sheath Block
(Abstracted from Br J Anaesth, 118(4):517–526, 2017)
This systematic review aimed to assess data from clinical trials to determine perioperative local anesthetic (LA) systemic concentrations following single-bolus transversus abdominis plane block (TAPB) or rectus sheath block (RSB) during abdominal surgery in order to improve our understanding of LA absorption and risk of toxicity following these blocks. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Pain Control Source Type: research
Preoperative Administration of Angiotensin-Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers: Do We Have Enough “VISION” to Stop It?
(Abstracted from Anesthesiology, 126(1):1–3, 2017)
There is significant controversy regarding administration of angiotensin-converting enzyme inhibitors (ACEIs) as well as angiotensin II receptor blockers (ARBs). This editorial comments on the study by Roshanov et al1 (“Withholding Versus Continuing Angiotensin-Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers Before Noncardiac Surgery: An Analysis of the Vascular events In noncardiac Surgery patIents cOhort evaluatioN Prospective Cohort”), which examined the large multinational, prospective Vascular events In noncardiac Surgery patIents cOhort eval...
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Preoperative and Postoperative Care Source Type: research
Withholding Versus Continuing Angiotensin-Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers Before Noncardiac Surgery: An Analysis of the Vascular Events in Noncardiac Surgery Patients Cohort Evaluation Prospective Cohort
(Abstracted from Anesthesiology, 126(1):16–27, 2017)
The purpose of this international prospective cohort study was to assess the effect of withholding angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) on the risk of 30-day composite outcome of all-cause death, myocardial injury following noncardiac surgery (MINS), and stroke, as well as to determine the relationship between withholding ACEIs/ARBs and perioperative hypotension. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Preoperative and Postoperative Care Source Type: research
Postoperative Orthostatic Intolerance: A Common Perioperative Problem With Few Available Solutions
(Abstracted from Can J Anaesth, 64(1):10–15, 2017)
This editorial provides an overview of postoperative orthostatic intolerance (OI) with an update and perspective on the current knowledge and potential mitigation measures. Postoperative OI symptoms include dizziness, blurred vision, nausea, vomiting, or syncope during sitting or standing. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Preoperative and Postoperative Care Source Type: research
Objective Model Using Only Gender, Age and Medication List Predicts In-hospital Morbidity After Elective Surgery
(Abstracted from Br J Anaesth, 118(4):544–550, 2017)
Using a retrospective single-center database study, a risk-evaluation tool for elective surgery was devised. This neutral prognostic tool of in-hospital postoperative morbidity used commonly available data, such as sex, age, and list of medications to assess risk without depending on laboratory tests or complex diagnoses. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Preoperative and Postoperative Care Source Type: research
Implementing a Statistical Model for Protamine Titration: Effects on Coagulation in Cardiac Surgical Patients
(Abstracted from J Cardiothorac Vasc Anesth, 31:516–21, 2017)
Using a fixed protamine-heparin dose (1:1) is the most commonly used method of protamine dosing in cardiopulmonary bypass patients to reverse the effects of heparin. The hemostasis management system (HMS Plus; Medtronic, Minneapolis, Minn) is an accepted alternate point-of-care device to calculate protamine dosing. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Pharmacology Source Type: research
Trends in Tramadol: Pharmacology, Metabolism, and Misuse
(Abstracted from Anesth Analg, 124(1):44–51, 2017)
The purpose of this review was to examine the literature published over the period January 1980 to January 2016 regarding the use of tramadol for treatment of moderate to moderately severe chronic pain. Tramadol is a synthetic opioid medication with monoaminergic actions and a mechanism similar to serotonin-norepinephrine reuptake inhibitors. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Pharmacology Source Type: research
Pharmacogenomics and Pharmacogenetics for the Intensive Care Unit: A Narrative Review
(Abstracted from Can J Anaesth, 64(1):45–64, 2017)
The main aim of this article was to review the important concepts, examples, and clinically relevant applications of pharmacogenetics and pharmacogenomics for drugs encountered in the intensive care unit (ICU). (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Pharmacology Source Type: research
Monkey in the Middle: Translational Studies of Pediatric Anesthetic Exposure
(Abstracted from Anesthesiology, 126(1):6–8, 2017)
Preclinical animal studies have resulted in retrospective and prospective studies in humans regarding the safety of pediatric anesthesia. The possibility of adverse neurocognitive outcomes associated with repeated or prolonged pediatric anesthesia is worrisome. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Pediatric Anesthesia Source Type: research
Isoflurane Anesthesia Has Long-term Consequences on Motor and Behavioral Development in Infant Rhesus Macaques
(Abstracted from Anesthesiology, 126(1):74–84, 2017)
The purpose of this trial was to examine isoflurane exposure in children utilizing the nonhuman primate (NHP) model. This translational research is important because there is significant experimental evidence that anesthetic exposure correlates with neural cell injury and neuron death in the developing brain. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Pediatric Anesthesia Source Type: research
Paediatric Emergence Delirium: A Comprehensive Review and Interpretation of the Literature
This article considers the evolution of emergence delirium (ED) and emergence agitation since it was first identified in the 1960s to assess present and future trends in identification, treatment, and prognostic value. There is a need for well-designed large prospective studies to assess ED risk factors and eliminate confounders as well as a need for standardized screening, evaluation tools, and data sharing in order to easily compare outcomes for researchers of pediatric ED (characterized by crying, sobbing, thrashing about, and disorientation following anesthesia). (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Pediatric Anesthesia Source Type: research
Anesthetic and Obstetrical Factors Associated With the Effectiveness of Epidural Analgesia for Labor Pain Relief: An Observational Population-Based Study
(Abstracted from Reg Anesth Pain Med, 42(1):109–116, 2017)
Epidural analgesia is considered the criterion standard for pain relief during labor because of its high rate of maternal satisfaction and minimal adverse effects for both mother and child. However, pain relief during labor is also a complex issue, and there continue to be efforts to improve epidural analgesia. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research
Vital Signs and Other Observations Used to Detect Deterioration in Pregnant Women: An Analysis of Vital Sign Charts in Consultant-Led UK Maternity Units
(Abstracted from Int J Obstet Anesth, 30:44–51, 2017)
The main objective of this study was to assess early warning charts routinely used in the United Kingdom and the Channel Islands' consultant-led maternity units so as to determine the maternal vital sign values deemed normal in their obstetric early warning systems (ObsEWS), as well as identify the triggers and protocols for escalated care. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research
Anesthetic Considerations for Labor and Delivery in Women With Cerebrospinal Fluid Shunts
(Abstracted from Int J Obstet Anesth, 30:23–29, 2017)
The main objective of this literature review was to assess anesthetic techniques and complications associated with pregnant women with cerebrospinal fluid (CSF) shunts. Hydrocephalus, generally associated with abnormal physiology of CSF production or outflow, has multiple developmental and acquired causes. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research
Anaesthesia for Abnormally Invasive Placenta: A Single-Institution Case Series
(Abstracted from Int J Obstet Anesth, 30:10–15, 2017)
The purpose of this retrospective study is to present details of anesthetic management and outcomes for abnormally invasive placenta (AIP) with data over a 5-year period (January 2011–2016) from the John Radcliffe Hospital, tertiary-referral maternity unit in Oxford, United Kingdom. Cases of AIP were identified using the standard International Classification of Diseases, 10th Revision codes for placenta accreta, placenta increta, and placenta percreta (O43.2: morbidly adherent placenta). (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - August 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research
