Effectiveness of an Electronic Alert for Hypotension and Low Bispectral Index on 90-Day Postoperative Mortality: A Prospective, Randomized Trial
(Abstracted from Anesthesiology, 125(6):1113–1120, 2016)
Postoperative mortality is associated with the combination of low end-organ perfusion pressure, deep hypnosis, and low volatile anesthetic concentration. Some studies have shown a link between mortality and the cumulative duration of a “triple low” defined as a low mean arterial pressure (MAP), low bispectral index (BIS), low end-tidal minimum alveolar concentration. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Techniques and Monitoring Source Type: research
Clonidine Does Not Reduce Pain or Opioid Consumption After Noncardiac Surgery
(Abstracted from Anesth Analg, 123:749–757, 2016)
A multimodal technique using differing classes of nonopioid analgesics to reduce pain after surgery can improve recovery and reduce opioid requirements. Clonidine, an α2-adrenoceptor agonist, is often used as part of a multimodal analgesic technique. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Pain Control Source Type: research
Continuous Ambulatory Adductor Canal Catheters for Patients Undergoing Knee Arthroplasty Surgery
(Abstracted from J Clin Anesth, 35:190–194, 2016)
This case series was conducted to examine the feasibility of the use of ambulatory adductor canal catheter for patients being discharged on postoperative day (POD) 1 following total knee arthroplasty (TKA). Incorporation of adductor canal blocks (ACBs) and enhanced recovery after orthopedic surgery pathways into patient care have led to reduced hospital length of stay in patients undergoing TKA, sometimes making patient discharge on POD1 possible. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Pain Control Source Type: research
Genetic Polymorphisms and Their Association With the Prevalence and Severity of Chronic Postsurgical Pain: A Systematic Review
(Abstracted from Br J Anaesth, 117(6):708–719, 2016)
Several studies have been conducted to determine the risk factors for the development of chronic postsurgical pain (CPSP), which is common following any kind of surgery (prevalence of 10%–60%). Chronic postsurgical pain adversely affects the quality of life of patients and has significant socioeconomic impact. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Pain Control Source Type: research
Operating Room Discharge After Deep Neuromuscular Block Reversed With Sugammadex Compared With Shallow Block Reversed With Neostigmine: A Randomized Controlled Trial
(Abstracted from J Clin Anesth, 35:107–113, 2016)
Deep neuromuscular blockade (NMB) can often provide improved surgical conditions, particularly during laparoscopic procedures. With the availability of sugammadex, maintenance of a moderate to deep NMB with rocuronium can be reversed more rapidly and consistently at the end of the surgical procedure. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Pharmacology Source Type: research
Fibrinogen Supplementation Ex Vivo Increases Clot Firmness Comparable to Platelet Transfusion in Thrombocytopenia
This study investigates how the use of fibrinogen concentrate ex vivo compares to the use of in vivo platelet transfusion (PT) to improve clot firmness in patients with thrombocytopenia (platelet count (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Pharmacology Source Type: research
Anesthesia-Related Carbon Monoxide Exposure: Toxicity and Potential Therapy
This article aims to detail anesthesia-related carbon monoxide (CO) exposure, identify its sources, review the mechanisms of overt CO toxicity, highlight the cytoprotective effect of low-dose CO at the cellular level, and discuss the potential therapeutic role for CO in routine anesthetic management. Both exogenous and endogenous sources of CO exposure are detailed here with an overview of the biologic effects of the gas and policy regarding the exposure and its overt toxicity. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Perioperative Complications Source Type: research
Good News: But Why Is the Incidence of Postoperative Ischemic Optic Neuropathy Falling?
(Abstracted from Anesthesiology, 125:445–448, 2016)
Postoperative visual loss (POVL) after spinal surgery began to become a concern in the 1990s and led to the American Society of Anesthesiologists POVL Registry in 1999. Most of these result from ischemic optic neuropathy (ION). (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Perioperative Complications Source Type: research
Perioperative Visual Loss in Spine Fusion Surgery: Ischemic Optic Neuropathy in the United States From 1998 to 2012 in the Nationwide Inpatient Sample
(Abstracted from Anesthesiology, 125(3):457–464, 2016)
The number of patients undergoing spinal fusion surgery in the United States is the highest in the world. Developing perioperative visual loss as a result of ischemic optic neuropathy (ION) is a rare complication. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Perioperative Complications Source Type: research
Perioperative Aspirin for Prevention of Venous Thromboembolism: The PeriOperative ISchemia Evaluation-2 Trial and a Pooled Analysis of the Randomized Trials
(Abstracted from Anesthesiolog, 125(6):1121–1129, 2016)
Venous thromboembolism (VTE) occurs in 1% to 5% of noncardiac surgery patients in the 30 days following surgery without the use of routine thromboprophylaxis, thereby emphasizing the importance of postoperative VTE prevention. Aspirin is generally preferred over other anticoagulants because of its low cost and because it is already being taken by many patients preoperatively. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Perioperative Complications Source Type: research
Choosing Wisely and Preoperative Hemoglobin A1c Testing: What Should It Mean?
(Abstracted from Can J Anaesth, 63(12):1307–1313, 2016)
To promote high-value care and improved use of health system resources, the Canadian Anesthesiologists’ Society and Choosing Wisely Canada recommended that routine preoperative testing should be avoided in surgical populations when the results would be unbeneficial or when testing might lead to complications secondary to false-positive results. These recommendations include not performing preoperative serum biochemistry tests (including blood glucose assays) in asymptomatic patients undergoing low-risk, noncardiac surgery. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Perioperative Complications Source Type: research
Postoperative Dysglycemia in Elective Non-diabetic Surgical Patients: A Prospective Observational Study
(Abstracted from Can J Anaesth, 63(12):1319–1334, 2016)
Diabetic surgical patients are at an increased risk of postoperative morbidity and mortality secondary to their associated comorbidities and the potential complications of an increased blood glucose level. These risks warrant the use of greater health care resources to help prevent them. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Perioperative Complications Source Type: research
Anesthesia Kills Brain Cells, But What Does It Mean?
(Abstracted from Anesthesiology, 125(6):1090–1091, 2016)
Neurocognitive dysfunction following early exposure to anesthesia is an area of concern for anesthesiologists. Recent studies including the General Anaesthesia and Awake–Regional Anaesthesia in Infancy and the Pediatric Anesthesia Neurodevelopment Assessment trials have indicated that short duration/exposure to general anesthesia does not result in serious consequences in very young children. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Pediatric Anesthesia Source Type: research
Long-term Fate Mapping to Assess the Impact of Postnatal Isoflurane Exposure on Hippocampal Progenitor Cell Productivity
(Abstracted from Anesthesiology, 125(6):1159–1170, 2016)
Anesthesia exposure at a young age in animal models has been associated with brain cell death. However, recent human studies have indicated no identifiable neurocognitive deficits in children after short-duration exposure to general anesthesia in infancy. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Pediatric Anesthesia Source Type: research
Sugammadex Given for Rocuronium-Induced Neuromuscular Blockade in Infants: A Retrospective Study
The objective of this retrospective, observational study was to evaluate the efficacy and safety of sugammadex for the reversal of profound neuromuscular blockade by rocuronium in infant patients. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Pediatric Anesthesia Source Type: research
