The shift work and health research agenda: Considering changes in gut microbiota as a pathway linking shift work, sleep loss and circadian misalignment, and metabolic disease
Prevalence and impact of metabolic disease is rising. In particular, overweight and obesity are at epidemic levels and are a leading health concern in the Western world. Shift work increases the risk of overweight and obesity, along with a number of additional metabolic diseases, including metabolic syndrome and type 2 diabetes (T2D). How shift work contributes to metabolic disease has not been fully elucidated. Short sleep duration is associated with metabolic disease and shift workers typically have shorter sleep durations. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - July 10, 2016 Category: Sleep Medicine Authors: Amy C. Reynolds, Jessica L. Paterson, Sally A. Ferguson, Dragana Stanley, Kenneth P. Wright, Drew Dawson Source Type: research

Can Exercise Regulate the Circadian System of Adolescents? Novel Implications for the Treatment of Delayed Sleep-Wake Phase Disorder
Adolescents are vulnerable to inadequate sleep due to a unique constellation of risk factors. In particular, the puberty-related phase delay in the timing of the circadian system postpones the onset of sleep. Resultantly, disordered sleep is common among teenagers and young adults, with the most common sleep problem being Delayed Sleep Wake Phase Disorder (DSWPD). Although current treatments for DSWPD show promise, novel ways to improve our youth ’s sleep are needed. The purpose of this review is to critically evaluate the evidence for the role of exercise as a method to shift and/or regulate circadian timing, and thus i...
Source: Sleep Medicine Reviews - July 10, 2016 Category: Sleep Medicine Authors: C.E. Richardson, M. Gradisar, M.A. Short, C. Lang Tags: Clinical Review Source Type: research

The shift work and health research agenda: Considering changes in gut microbiota as a pathway linking shift work, sleep loss and circadian misalignment, and metabolic disease
Prevalence and impact of metabolic disease is rising. In particular, overweight and obesity are at epidemic levels and are a leading health concern in the Western world. Shift work increases the risk of overweight and obesity, along with a number of additional metabolic diseases, including metabolic syndrome and type 2 diabetes (T2D). How shift work contributes to metabolic disease has not been fully elucidated. Short sleep duration is associated with metabolic disease and shift workers typically have shorter sleep durations. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - July 10, 2016 Category: Sleep Medicine Authors: Amy C. Reynolds, Jessica L. Paterson, Sally A. Ferguson, Dragana Stanley, Kenneth P. Wright, Drew Dawson Source Type: research

Can Exercise Regulate the Circadian System of Adolescents? Novel Implications for the Treatment of Delayed Sleep-Wake Phase Disorder
Adolescents are vulnerable to inadequate sleep due to a unique constellation of risk factors. In particular, the puberty-related phase delay in the timing of the circadian system postpones the onset of sleep. Resultantly, disordered sleep is common among teenagers and young adults, with the most common sleep problem being Delayed Sleep Wake Phase Disorder (DSWPD). Although current treatments for DSWPD show promise, novel ways to improve our youth’s sleep are needed. The purpose of this review is to critically evaluate the evidence for the role of exercise as a method to shift and/or regulate circadian timing, and thus im...
Source: Sleep Medicine Reviews - July 10, 2016 Category: Sleep Medicine Authors: C.E. Richardson, M. Gradisar, M.A. Short, C. Lang Tags: Clinical Review Source Type: research

Chronotype and circadian rhythm in bipolar disorder: a systematic review
Despite a complex relationship between mood, sleep and rhythm, the impact of circadian disruptions on bipolar disorder (BD) has not been clarified. The purpose of this systematic review was to define current evidence regarding chronotype and circadian rhythm patterns in BD patients. Forty-two studies were included, involving 3,432 BD patients. Disruption of the biological rhythm was identified, even in drug-na ïve BD patients and independently of mood status. Daily profiles of melatonin levels and cortisol indicated a delayed phase. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - June 30, 2016 Category: Sleep Medicine Authors: Matias Carvalho Aguiar Melo, Rafael Le ônidas Cristino Abreu, Vicente Bezerra Linhares Neto, Pedro Felipe Carvalhedo de Bruin, Veralice Meireles Sales de Bruin Tags: Clinical Review Source Type: research

Somatic and Neuropsychiatric Comorbidities in Pediatric Restless Legs Syndrome: A Systematic Review of the Literature
Restless legs syndrome (RLS) is a relatively common neurological disorder in childhood, although it is usually overlooked due to the atypical presentation in children and associated comorbid conditions that may affect its clinical presentation. Here, we aimed to perform, for the first time, a systematic review of studies reporting the association between RLS in children and adolescents ( < 18 years) and somatic or neuropsychiatric conditions. We searched for peer-reviewed studies in PubMed, Ovid (including PsycINFO, Ovid MEDLINE ®, and Embase), Web of Knowledge (Web of Science, Biological abstracts, BIOSIS, FSTA) through ...
Source: Sleep Medicine Reviews - June 30, 2016 Category: Sleep Medicine Authors: Marco Angriman, Samuele Cortese, Oliviero Bruni Tags: Clinical Review Source Type: research

Chronotype and circadian rhythm in bipolar disorder: a systematic review
Despite a complex relationship between mood, sleep and rhythm, the impact of circadian disruptions on bipolar disorder (BD) has not been clarified. The purpose of this systematic review was to define current evidence regarding chronotype and circadian rhythm patterns in BD patients. Forty-two studies were included, involving 3,432 BD patients. Disruption of the biological rhythm was identified, even in drug-naïve BD patients and independently of mood status. Daily profiles of melatonin levels and cortisol indicated a delayed phase. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - June 30, 2016 Category: Sleep Medicine Authors: Matias Carvalho Aguiar Melo, Rafael Leônidas Cristino Abreu, Vicente Bezerra Linhares Neto, Pedro Felipe Carvalhedo de Bruin, Veralice Meireles Sales de Bruin Tags: Clinical Review Source Type: research

Somatic and Neuropsychiatric Comorbidities in Pediatric Restless Legs Syndrome: A Systematic Review of the Literature
Restless legs syndrome (RLS) is a relatively common neurological disorder in childhood, although it is usually overlooked due to the atypical presentation in children and associated comorbid conditions that may affect its clinical presentation. Here, we aimed to perform, for the first time, a systematic review of studies reporting the association between RLS in children and adolescents ( (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - June 30, 2016 Category: Sleep Medicine Authors: Marco Angriman, Samuele Cortese, Oliviero Bruni Tags: Clinical Review Source Type: research

Heart rate variability in insomnia patients: a critical review of the literature
Heart rate variability (HRV) is an objective marker that provides insight into autonomic nervous system dynamics. There is conflicting evidence regarding the presence of HRV impairment in insomnia patients. Web-based databases were used to systematically search the literature for all studies that compared the HRV of insomnia patients to controls or reported the HRV of insomnia patients before and after an intervention. 22 relevant papers were identified. Study characteristics were summarised, HRV measures were extracted and a risk of bias assessment for each study was performed. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - June 26, 2016 Category: Sleep Medicine Authors: Kirsty L. Dodds, Christopher B. Miller, Simon D. Kyle, Nathaniel S. Marshall, Christopher J. Gordon Tags: Clinical Review Source Type: research

Brain imaging findings in idiopathic REM sleep behavior disorder (RBD) – A systematic review on potential biomarkers for neurodegeneration
Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by the loss of physiological atonia of skeletal muscles with abnormal behavior during dream sleep. RBD may be the initial manifestation of neurodegenerative diseases, particularly of α-synucleinopathies such as Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). However, gauging the individual risk of subsequent phenoconversion and making assumptions on the type of disease that may subsequently follow RBD is challenging. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - June 24, 2016 Category: Sleep Medicine Authors: Julia Heller, Nikolina Brcina, Imis Dogan, Florian Holtbernd, Sandro Romanzetti, J örg B. Schulz, Johannes Schiefer, Kathrin Reetz Tags: Clinical review Source Type: research

Brain imaging findings in idiopathic REM sleep behavior disorder (RBD) - a systematic review on potential biomarkers for neurodegeneration -
Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by the loss of physiological atonia of skeletal muscles with abnormal behavior during dream sleep. RBD may be the initial manifestation of neurodegenerative diseases, particularly of α-synucleinopathies such as Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). However, gauging the individual risk of subsequent phenoconversion and making assumptions on the type of disease that may subsequently follow RBD is challenging. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - June 24, 2016 Category: Sleep Medicine Authors: Julia Heller, Nikolina Brcina, Imis Dogan, Florian Holtbernd, Sandro Romanzetti, J örg B. Schulz, Johannes Schiefer, Kathrin Reetz Tags: Clinical Review Source Type: research

Reply to “Sleep, mortality and beyond: A magician can't pull more from the hat than has been put in earlier”
Thanks to Erren et  al. for their complements on our work on sleep duration and risk of all-cause mortality [1]. The proposed concept “sleep-year-index” by Erren et al. [2] probably makes sense when establishing the relationship between sleep and diseases. And we agree with their view that accumulated sleep disr uptions could be tested as another alternative measure in sleep research, which is valuable and feasible. However, we also hold some opposite opinions. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - June 21, 2016 Category: Sleep Medicine Authors: Chang Xu, Xiang-Yu Meng, Tong-Zu Liu Tags: Reply Source Type: research