The clinical spectrum of childhood narcolepsy
Narcolepsy type 1 is a life-long, severe, multifaceted disease often arising in childhood or adolescence. Beyond the classical symptoms (excessive daytime sleepiness, cataplexy, hallucinations, sleep paralysis and nocturnal fragmented sleep), metabolic, endocrinological, psychiatric and psychosocial aspects must be considered. Despite the increased awareness after H1N1 pandemic influenza and vaccination, narcolepsy is still misdiagnosed and unrecognized. The peculiar presentation of symptoms in narcoleptic children could in part explain the misdiagnoses. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - May 8, 2017 Category: Sleep Medicine Authors: Emanuela Postiglione, Elena Antelmi, Fabio Pizza, Michel Lecendreux, Yves Dauvilliers, Giuseppe Plazzi Tags: Clinical Review Source Type: research

Cognitive Behavioral Therapy for Insomnia (CBT-I): What is known, and advancing the science by avoiding the pitfalls of the placebo effect
Research support: NIMH MH095776-01, American Foundation for Suicide Prevention DIG-0-087-13, Merck, MECTA. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - May 5, 2017 Category: Sleep Medicine Authors: W.Vaughn McCall Tags: Guest editorial Source Type: research

Driving simulators in the clinical assessment of fitness to drive in sleepy individuals: a systematic review
Road traffic injuries are projected to be the leading cause of death for those aged between 15 and 29 years by the year 2030, and sleepiness is estimated to be the underlying cause in up to 15-20% of all motor vehicle accidents. Sleepiness at the wheel is most often caused by socially induced sleep deprivation or poor sleep hygiene in otherwise healthy individuals, medical disorders, or the intake of drugs. Validated methods for objectifying sleepiness are urgently sought, particularly in the context of driving. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - May 4, 2017 Category: Sleep Medicine Authors: David R. Schreier, Christina Banks, Johannes Mathis Tags: Clinical Review Source Type: research

Adherence to positive airway pressure treatment among minority populations in the US: a scoping review
Minority individuals in the United States (US) have an increased prevalence of obstructive sleep apnea syndrome (OSA) compared to their white/Caucasian counterparts. In general, adherence to positive airway pressure (PAP) therapy is poor and some studies suggest that PAP use among minority individuals is inferior to that of whites. However, there has not been a review of the evidence that addresses racial-ethnic disparities for PAP adherence in the treatment of OSA, and no review has systematically examined the contributing factors to poor adherence among minority individuals compared to whites. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - April 13, 2017 Category: Sleep Medicine Authors: Douglas M. Wallace, Natasha J. Williams, Amy M. Sawyer, Girardin Jean-Louis, Mark S. Aloia, Dorice L. Vieira, William K. Wohlgemuth Tags: Clinical Review Source Type: research

Validity of the Berlin questionnaire in detecting obstructive sleep apnea: A systematic review and meta-analysis
We aimed to systematically review the Berlin questionnaire as a screening tool for obstructive sleep apnea. We systematically searched PubMed, Embase, and Scopus databases, reviewed articles reporting the Berlin questionnaire's diagnostic utility as measured against type-1 polysomnography, and performed meta-analyses where possible. Thirty five eligible articles showed that the Berlin questionnaire's diagnostic utility varied by study population, definition of hypopnea used, and apnea-hypopnea index threshold used. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - April 7, 2017 Category: Sleep Medicine Authors: Chamara V. Senaratna, Jennifer L. Perret, Melanie C. Matheson, Caroline J. Lodge, Adrian J. Lowe, Raisa Cassim, Melissa A. Russell, John A. Burgess, Garun S. Hamilton, Shyamali C. Dharmage Tags: Clinical Review Source Type: research

Validity of the Berlin questionnaire in detecting obstructive sleep apnoea: A systematic review and meta-analysis
We aimed to systematically review the Berlin questionnaire as a screening tool for obstructive sleep apnea. We systematically searched PubMed, Embase, and Scopus databases, reviewed articles reporting the Berlin questionnaire ’s diagnostic utility as measured against type-1 polysomnography, and performed meta-analyses where possible. Thirty five eligible articles showed that the Berlin questionnaire’s diagnostic utility varied by study population, definition of hypopnea used, and apnea-hypopnea index threshold used. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - April 7, 2017 Category: Sleep Medicine Authors: Chamara V. Senaratna, Jennifer L. Perret, Melanie C. Matheson, Caroline J. Lodge, Adrian J. Lowe, Raisa Cassim, Melissa Russell, John Burgess, Garun S. Hamilton, Shyamali C. Dharmage Tags: Clinical Review Source Type: research

Not Only Limbs in Atypical Restless Legs Syndrome
Restless legs syndrome (RLS) typically affects the limbs, but the involvement of other body parts has also been reported. In this assay, we critically review all literature reports of atypical RLS cases with unusual localizations. Applying the updated diagnostic criteria of the International Restless Legs Syndrome Study Group (IRLSSG), which also consider symptoms localized outside of the lower limbs, a few of these atypical cases reported in the previous literature resulted in a definitive diagnosis of RLS. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - April 4, 2017 Category: Sleep Medicine Authors: Alessandra Turrini, Alberto Raggi, Giovanna Calandra-Buonaura, Paolo Martinelli, Raffaele Ferri, Federica Provini Tags: Clinical Review Source Type: research

A systematic review and meta-analysis of placebo versus no treatment for insomnia symptoms
This systematic review and meta-analysis aimed to determine the size of the placebo effect for insomnia symptoms when comparing placebo treatment with no treatment. PsycINFO, MEDLINE, and CINAHL databases were systematically searched for studies allocating participants with insomnia symptoms (diagnosed or self-reported) to receive a placebo that they were led to believe was an active treatment or to a no treatment control group. Thirteen independent studies (n=566) met inclusion criteria. Meta-analysis indicated a reliable placebo effect whereby placebo treatment led to improved percevied sleep onset latency (SOL; Hedges g...
Source: Sleep Medicine Reviews - April 3, 2017 Category: Sleep Medicine Authors: Valerie Yeung Shi Chung, Louise Sharpe, N. Glozier, M.L. Hackett, Ben Colagiuri Tags: Clinical Review Source Type: research

What more can we learn about sleep education programs in young people?
It has been clearly documented in the paediatric and sleep medicine literature and in recognised bodies [1-3], that sleep health has become an important public health issue and more importantly that young people worldwide face challenges in achieving and maintaining enough sleep. Increasing awareness about the importance of sleep, the effects of poor sleep heath and preventative and/or treatment modalities for improving sleep health have been largely delivered through school based sleep education programs which have been reviewed and critiqued over recent years [4-6]. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - March 31, 2017 Category: Sleep Medicine Authors: Sarah Blunden Source Type: research

Aims and Scope and Editorial Board
(Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - March 29, 2017 Category: Sleep Medicine Source Type: research

Cognitive deficits in obstructive sleep apnea: insights from a meta-review and comparison with deficits observed in COPD, insomnia, and sleep deprivation
Obstructive sleep apnea (OSA) is a nocturnal breathing disorder that is associated with cognitive impairment. The primary determinants of cognitive deficits in OSA are thought to be sleep disruption and blood gas abnormalities. Cognitive impairment is also seen in other disorders that are characterised primarily by sleep disturbance (e.g., sleep restriction/deprivation, insomnia) or hypoxia/hypercarbia (e.g. chronic obstructive pulmonary disease (COPD). Assessment of the cognitive defects observed in these other disorders could help better define the mechanisms underlying cognitive deficits in OSA. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - March 29, 2017 Category: Sleep Medicine Authors: Michelle Olaithe, Romola S. Bucks, David R. Hillman, Peter R. Eastwood Tags: Clinical Review Source Type: research

Gender differences in obstructive sleep apnoea, insomnia and restless legs syndrome in adults – What do we know? A clinical update
Research in sleep medicine over the last decades has involved a broad variety of sleep disorders in both men and women. Gender differences have been identified in sleep physiology as well as in the three most common sleep disorders: obstructive sleep apnoea (OSA), insomnia and restless legs syndrome (RLS). However, research on gender differences in sleep medicine appears limited. This clinical review aims to give an updated overview of gender differences, in relation to prevalence, clinical presentation, treatment and quality of life in OSA, insomnia and RLS. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - March 25, 2017 Category: Sleep Medicine Authors: Jenny Theorell-Hagl öw, Christopher B. Miller, Delwyn J. Bartlett, Brendon J. Yee, Hannah D. Openshaw, Ronald R. Grunstein Tags: Clinical Review Source Type: research

Gender differences in obstructive sleep apnoea, insomnia and restless legs syndrome in adults - what do we know? A clinical update
Research in sleep medicine over the last decades has involved a broad variety of sleep disorders in both men and women. Gender differences have been identified in sleep physiology as well as in the three most common sleep disorders: obstructive sleep apnoea (OSA), insomnia and restless legs syndrome (RLS). However, research on gender differences in sleep medicine appears limited. This clinical review aims to give an updated overview of gender differences, in relation to prevalence, clinical presentation, treatment and quality of life in OSA, insomnia and RLS. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - March 25, 2017 Category: Sleep Medicine Authors: Jenny Theorell-Hagl öw, Christopher B. Miller, Delwyn J. Bartlett, Brendon J. Yee, Hannah D. Openshaw, Ronald R. Grunstein Tags: Clinical Review Source Type: research

To screen or not to screen for obstructive sleep apnea, that is the question
Screening tests are widely used, either in low disease prevalence populations, e.g. breast cancer screening, or more focused screening in patients declaring symptoms suggestive of a disease, such as CT coronary angiography for patients with chest pain. Three papers in this journal look at screening for obstructive sleep apnea (OSA) using questionnaires in varied populations with very different prevalences of OSA. However, there is surprisingly little evidence that such activities are valuable, or that they should divert resources away from patients with symptomatic OSA. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - March 22, 2017 Category: Sleep Medicine Authors: Chris Turnbull, John Stradling Tags: Editorial Source Type: research