Tumor Necrosis Factor Alpha in Sleep Regulation
This review details tumor necrosis factor alpha (TNF) biology and its role in sleep, and describes how TNF medications influence sleep/wake activity. Substantial evidence from healthy young animals indicates acute enhancement or inhibition of endogenous brain TNF respectively promotes and inhibits sleep. In contrast, the role of TNF in sleep in most human studies involves pathological conditions associated with chronic elevations of systemic TNF and disrupted sleep. Normalization of TNF levels in such patients improves sleep. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 25, 2017 Category: Sleep Medicine Authors: Matthew Rockstrom, Liangyu Chen, Ping Taishi, Joseph T. Nguyen, Cody M. Gibbons, Sigrid Veasey, James M. Krueger Source Type: research

Anesthesia and Sleep Apnea
Due to its low rate of diagnosis, in the general population over half of those experiencing Obstructive Sleep Apnea (OSA) are unaware that they have the condition. However, any acute medical event may exacerbate OSA and could have serious health consequences. In this context the management of the perioperative period, from anesthesia through the surgery itself and into the postoperative period, is more problematic for patients with sleep disordered breathing than for others. There is prolific literature in this area although large randomized trials are few due to the high sample size needed and possible ethical difficultie...
Source: Sleep Medicine Reviews - October 25, 2017 Category: Sleep Medicine Authors: Renaud Tamisier, Fanny Fabre, Fergal O ’Donoghue, Patrick Lévy, Jean-François Payen, Jean-Louis Pépin Tags: Clinical Review Source Type: research

Prevalence of restless legs syndrome during pregnancy: a systematic review and meta-analysis
Pregnant women are more likely to be affected by restless legs syndrome (RLS) than the general population. Restless legs syndrome during pregnancy is associated with adverse maternal and fetal outcomes. Currently unknown is the worldwide and regional prevalence of RLS in pregnant women. We performed a meta-analysis to provide a full profile of the prevalence of RLS during pregnancy. A systematic search of the PubMed, Medline, EMBASE, and Web of Science databases was performed to identify studies that were published up to April 2017, followed by random-effects meta-analyses. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 25, 2017 Category: Sleep Medicine Authors: Si-Jing Chen, Le Shi, Yan-Ping Bao, Ye-Kun Sun, Xiao Lin, Jian-Yu Que, Michael V. Vitiello, Yu-Xin Zhou, Yong-Qing Wang, Lin Lu Tags: Clinical Review Source Type: research

The influence of sleep on human hypothalamic –pituitary–adrenal (HPA) axis reactivity: A systematic review
Inadequate sleep is highly prevalent and known to decline both physical- and mental health. Literature suggests that altered functioning of the hypothalamic –pituitary–adrenal (HPA) axis might underlie this association. This assumption is mainly based on changes in basal neuroendocrine activity and it is of equal importance to elucidate whether sleep may also influence HPA stress responsiveness. The present review provides a complete outline of rece nt human studies that have investigated how different aspects of sleep influence cortisol reactivity to laboratory stress. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 17, 2017 Category: Sleep Medicine Authors: Jens H. van Dalfsen, C. Rob Markus Tags: Clinical Review Source Type: research

The influence of sleep on human hypothalamic-pituitary-adrenal (HPA) axis reactivity: a systematic review
Inadequate sleep is highly prevalent and known to decline both physical- and mental health. Literature suggests that altered functioning of the hypothalamic-pituitary-adrenal (HPA) axis might underlie this association. This assumption is mainly based on changes in basal neuroendocrine activity and it is of equal importance to elucidate whether sleep may also influence HPA stress responsiveness. The present review provides a complete outline of recent human studies that have investigated how different aspects of sleep influence cortisol reactivity to laboratory stress. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 17, 2017 Category: Sleep Medicine Authors: Jens H. van Dalfsen, C.Rob Markus Tags: Clinical Review Source Type: research

Prone sleeping position in infancy: Implications for cardiovascular and cerebrovascular function
Advances in neonatal care have improved the survival rates of preterm infants, however, the likelihood of brain injury and neurodevelopmental disability remains a significant problem. Whilst the etiology of preterm brain injury is complex, impairments in the cardio- and cerebro-vascular function have been implicated. During infancy, sleep is vital for brain development. However, instabilities in cardio- and cerebro-vascular function are most marked during sleep. Sleeping position is an important part of a safe sleeping environment. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 13, 2017 Category: Sleep Medicine Authors: Kelsee L. Shepherd, Stephanie R. Yiallourou, Rosemary S.C. Horne, Flora Y. Wong Tags: Clinical Review Source Type: research

Prone sleeping position in infancy: implications for cardiovascular and cerebrovascular function
Advances in neonatal care have improved the survival rates of preterm infants, however, the likelihood of brain injury and neurodevelopmental disability remains a significant problem. Whilst the etiology of preterm brain injury is complex, impairments in the cardio- and cerebro-vascular function have been implicated. During infancy, sleep is vital for brain development. However, instabilities in cardio- and cerebro-vascular function are most marked during sleep. Sleeping position is an important part of a safe sleeping environment. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 13, 2017 Category: Sleep Medicine Authors: Kelsee L. Shepherd, Stephanie R. Yiallourou, Rosemary SC. Horne, Flora Y. Wong Tags: Clinical Review Source Type: research

Short sleep duration and hyperglycemia in pregnancy: Aggregate and individual patient data meta-analysis
Short sleep duration has been linked to maternal hyperglycemia. Systematic review and meta-analysis were performed to evaluate the relationship between sleep duration and hyperglycemia in pregnancy or gestational diabetes (GDM). MEDLINE and Scopus were searched until July 2017. Studies that assessed sleep duration and had objective measurements of hyperglycemia during pregnancy were eligible. Aggregate data were available from eight studies, n  = 17,308 (seven with self-reported and one with objectively measured sleep duration). (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 5, 2017 Category: Sleep Medicine Authors: Sirimon Reutrakul, Thunyarat Anothaisintawee, Sharon J. Herring, Bilgay Izci Balserak, Isabelle Marc, Ammarin Thakkinstian Tags: Clinical Review Source Type: research

Short Sleep Duration and Hyperglycemia in Pregnancy: Aggregate and Individual Patient Data Meta-Analysis
Short sleep duration has been linked to maternal hyperglycemia. Systematic review and meta-analysis were performed to evaluate the relationship between sleep duration and hyperglycemia in pregnancy or gestational diabetes(GDM). Medline and Scopus were searched until July 2017. Studies that assessed sleep duration and had objective measurements of hyperglycemia during pregnancy were eligible. Aggregate data were available from eight studies, n=17,308 (seven with self-reported and one with objectively measured sleep duration). (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 5, 2017 Category: Sleep Medicine Authors: Sirimon Reutrakul, Thunyarat Anothaisintawee, Sharon J. Herring, Bilgay Izci Balserak, Isabelle Marc, Ammarin Thakkinstian Source Type: research

Sleep on your memory traces: How sleep effects can be explained by Act –In, a functional memory model
Numerous studies have explored the effect of sleep on memory. It is well known that a period of sleep, compared to a similar period of wakefulness, protects memories from interference, improves performance, and might also reorganize memory traces in a way that encourages creativity and rule extraction. It is assumed that these benefits come from the reactivation of brain networks, mainly involving the hippocampal structure, as well as from their synchronization with neocortical networks during sleep, thereby underpinning sleep-dependent memory consolidation and reorganization. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - September 30, 2017 Category: Sleep Medicine Authors: M élaine Cherdieu, Rémy Versace, Amandine E. Rey, Guillaume T. Vallet, Stéphanie Mazza Tags: Theoretical Review Source Type: research

Sleep on your memory traces: How sleep effects can be explained by Act-In, a functional memory model
Numerous studies have explored the effect of sleep on memory. It is well known that a period of sleep, compared to a similar period of wakefulness, protects memories from interference, improves performance, and might also reorganize memory traces in a way that encourages creativity and rule extraction. It is assumed that these benefits come from the reactivation of brain networks, mainly involving the hippocampal structure, as well as from their synchronization with neocortical networks during sleep, thereby underpinning sleep-dependent memory consolidation and reorganization. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - September 30, 2017 Category: Sleep Medicine Authors: M élaine Cherdieu, Rémy Versace, Amandine E. Rey, Guillaume T. Vallet, Stéphanie Mazza Tags: Theoretical Review Source Type: research

Cranial base length in pediatric populations with sleep disordered breathing: A systematic review
The aim of this study was to review the existing literature on the association between cranial base length (CBL) and sleep disordered breathing (SDB) in children. Searches were carried out using Ovid MEDLINE, EMBASE, and Science Citation Index. Modified NIH (National Institute of Health) quality assessment tool was used to assess risk of bias. Grading of recommendations, assessment, development and evaluation (GRADE) was used to summarize the quality of evidence. Six articles met the inclusion criteria. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - September 29, 2017 Category: Sleep Medicine Authors: Sahar Abtahi, Ashley Phuong, Paul W. Major, Carlos Flores-Mir Tags: Clinical Review Source Type: research

Cranial base length in pediatric populations with sleep disordered breathing: a systematic review
The aim of this study was to review the existing literature on the association between cranial base length (CBL) and sleep disordered breathing (SDB) in children. Searches were carried out using Ovid MEDLINE, EMBASE, and Science Citation Index. Modified NIH (National Institute of Health) quality assessment tool was used to assess risk of bias. Grading of recommendations, assessment, development and evaluation (GRADE) was used to summarize the quality of evidence. Six articles met the inclusion criteria. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - September 29, 2017 Category: Sleep Medicine Authors: Sahar Abtahi, Ashley Phuong, Paul W. Major, Carlos Flores Mir Tags: Clinical Review Source Type: research