Association between long sleep duration and increased risk of obesity and type 2 diabetes: A review of possible mechanisms
For the last two decades research has revealed an alarming association between short sleep duration and metabolic disorders. In tandem, the hormonal, behavioral, and genetic mechanisms underlying this relationship have been extensively investigated and reviewed. However, emerging evidence is revealing that excessive sleep duration has remarkably similar deleterious effects. Unfortunately, to date there has been little attention to what drives this connection. This narrative review therefore aims to summarize existing epidemiological findings, experimental work, and most importantly putative molecular and behavioral mechani...
Source: Sleep Medicine Reviews - November 20, 2017 Category: Sleep Medicine Authors: Xiao Tan, Colin D. Chapman, Jonathan Cedernaes, Christian Benedict Tags: Theoretical Review Source Type: research
A Heartfelt Goodbye and a Continuing Mission
I begin this introduction to SMR 2018 by announcing a major change for the Journal. My long-term editorial partner, Dr. Jean Krieger, SMR ’s founding Co-Editor and Editor-in-Chief for Europe and the Rest of the World for the last twenty years, decided to give up his incisive editorial pen and retire from SMR at the end of 2017. It is very safe to say that without Jean’s myriad of contributions to the Journal, SMR would not be the great and continuing success that it has become. Jean’s scientific acumen, editorial insight, remarkable work ethic and exquisite attention to detail all can be felt in every page of the Jou...
Source: Sleep Medicine Reviews - November 20, 2017 Category: Sleep Medicine Authors: Michael V. Vitiello Tags: Editorial Source Type: research
Association between long sleep duration and increased risk of obesity and type 2 diabetes: A review of possible mechanisms
For the last two decades research has revealed an alarming association between short sleep duration and metabolic disorders. In tandem, the hormonal, behavioral, and genetic mechanisms underlying this relationship have been extensively investigated and reviewed. However, emerging evidence is revealing that excessive sleep duration has remarkably similar deleterious effects. Unfortunately, to date there has been little attention to what drives this connection. This narrative review therefore aims to summarize existing epidemiological findings, experimental work, and most importantly putative molecular and behavioral mechani...
Source: Sleep Medicine Reviews - November 20, 2017 Category: Sleep Medicine Authors: Xiao Tan, Colin D. Chapman, Jonathan Cedernaes, Christian Benedict Source Type: research
Aims and Scope and Editorial Board
(Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 7, 2017 Category: Sleep Medicine Source Type: research
Benefits of a bedtime routine in young children: Sleep, development, and beyond
This paper presents a conceptual model and reviews the empirical evidence to support a nightly bedtime routine as a key factor in the promotion of not only healthy sleep, but also of broad development and wellbeing in early childhood. A bedtime routine embodies the characteristics of nurturing care and early child stimulation, which are deemed to be essential for positive outcomes, especially for at-risk children. Furthermore, common, adaptive components of a bedtime routine can contribute to an array of positive developmental outcomes beyond improved sleep, inclusive of language development, literacy, child emotional and ...
Source: Sleep Medicine Reviews - November 6, 2017 Category: Sleep Medicine Authors: Jodi A. Mindell, Ariel A. Williamson Tags: Theoretical Review Source Type: research
Phenotyping of PER3 variants reveals widespread effects on circadian preference, sleep regulation, and health
Period3 (Per3) is one of the most robustly rhythmic genes in humans and animals. It plays a significant role in temporal organisation in peripheral tissues. The effects of PER3 variants on many phenotypes have been investigated in targeted and genome-wide studies. PER3 variants, especially the human variable number tandem repeat (VNTR), associate with diurnal preference, mental disorders, non-visual responses to light, brain and cognitive responses to sleep loss/circadian misalignment. Introducing the VNTR into mice alters responses to sleep loss and expression of sleep homeostasis-related genes. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 6, 2017 Category: Sleep Medicine Authors: Simon N. Archer, Christina Schmidt, Gilles Vandewalle, Derk-Jan Dijk Tags: Physiological Review Source Type: research
Benefits of a Bedtime Routine in Young Children: Sleep, Development, and Beyond
This paper presents a conceptual model and reviews the empirical evidence to support a nightly bedtime routine as a key factor in the promotion of not only healthy sleep, but also of broad development and wellbeing in early childhood. A bedtime routine embodies the characteristics of nurturing care and early child stimulation, which are deemed to be essential for positive outcomes, especially for at-risk children. Furthermore, common, adaptive components of a bedtime routine can contribute to an array of positive developmental outcomes beyond improved sleep, inclusive of language development, literacy, child emotional and ...
Source: Sleep Medicine Reviews - November 6, 2017 Category: Sleep Medicine Authors: Jodi A. Mindell, Ariel A. Williamson Tags: Clinical Review Source Type: research
Extensive phenotyping of the effects of PER3 variants reveals widespread effects on circadian preference, sleep regulation, and health
Period3 (Per3) is one of the most robustly rhythmic genes in humans and animals. It plays a significant role in temporal organisation in peripheral tissues. The effects of PER3 variants on many phenotypes have been investigated in targeted and genome-wide studies. PER3 variants, especially the human variable number tandem repeat (VNTR), associate with diurnal preference, mental disorders, non-visual responses to light, brain and cognitive responses to sleep loss/circadian misalignment. Introducing the VNTR into mice alters responses to sleep loss and expression of sleep homeostasis-related genes. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - November 6, 2017 Category: Sleep Medicine Authors: Simon N. Archer, Christina Schmidt, Gilles Vandewalle, Derk-Jan Dijk Tags: Clinical Review Source Type: research
Cardiovascular effects of oral appliance therapy in obstructive sleep apnea: A systematic review and meta-analysis
This study systematically reviews the effects of oral appliance therapy (OAT) on a broad spectrum of cardiovascular outcomes.A literature search was performed up to December 31st 2016. Twenty-five relevant full-text articles were retrieved. Sixteen articles were considered methodologically sufficient, including 11 randomized controlled trials.Pooled data of the RCTs showed significant reductions in daytime systolic and diastolic blood pressure compared to baseline, but no significant reductions in heart rate, except for daytime heart rate when compared to inactive/placebo OAT. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 26, 2017 Category: Sleep Medicine Authors: Grietje E. de Vries, Peter J. Wijkstra, Ewout J. Houwerzijl, Huib A.M. Kerstjens, Aarnoud Hoekema Tags: Clinical Review Source Type: research
Cardiovascular Effects Of Oral Appliance Therapy In Obstructive Sleep Apnea: A Systematic Review And Meta-Analysis
This study systematically reviews the effects of oral appliance therapy (OAT) on a broad spectrum of cardiovascular outcomes.A literature search was performed up to December 31st 2016. Twenty-five relevant full-text articles were retrieved. Sixteen articles were considered methodologically sufficient, including 11 randomized controlled trials.Pooled data of the RCTs showed significant reductions in daytime systolic and diastolic blood pressure compared to baseline, but no significant reductions in heart rate, except for daytime heart rate when compared to inactive/placebo OAT. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 26, 2017 Category: Sleep Medicine Authors: Grietje.E. de Vries, Peter.J. Wijkstra, Ewout.J. Houwerzijl, Huib.A.M. Kerstjens, Aarnoud Hoekema Tags: Clinical Review Source Type: research
Prevalence of restless legs syndrome during pregnancy: A systematic review and meta-analysis
Pregnant women are more likely to be affected by restless legs syndrome (RLS) than the general population. Restless legs syndrome during pregnancy is associated with adverse maternal and fetal outcomes. Currently unknown is the worldwide and regional prevalence of RLS in pregnant women. We performed a meta-analysis to provide a full profile of the prevalence of RLS during pregnancy. A systematic search of the PubMed, Medline, EMBASE, and Web of Science databases was performed to identify studies that were published up to April 2017, followed by random-effects meta-analyses. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 25, 2017 Category: Sleep Medicine Authors: Si-Jing Chen, Le Shi, Yan-Ping Bao, Ye-Kun Sun, Xiao Lin, Jian-Yu Que, Michael V. Vitiello, Yu-Xin Zhou, Yong-Qing Wang, Lin Lu Tags: Clinical Review Source Type: research
Tumor necrosis factor alpha in sleep regulation
This review details tumor necrosis factor alpha (TNF) biology and its role in sleep, and describes how TNF medications influence sleep/wake activity. Substantial evidence from healthy young animals indicates acute enhancement or inhibition of endogenous brain TNF respectively promotes and inhibits sleep. In contrast, the role of TNF in sleep in most human studies involves pathological conditions associated with chronic elevations of systemic TNF and disrupted sleep. Normalization of TNF levels in such patients improves sleep. (Source: Sleep Medicine Reviews)
Source: Sleep Medicine Reviews - October 25, 2017 Category: Sleep Medicine Authors: Matthew D. Rockstrom, Liangyu Chen, Ping Taishi, Joseph T. Nguyen, Cody M. Gibbons, Sigrid C. Veasey, James M. Krueger Tags: Physiological Review Source Type: research
Anesthesia and sleep apnea
Due to its low rate of diagnosis, in the general population over half of those experiencing obstructive sleep apnea (OSA) are unaware that they have the condition. However, any acute medical event may exacerbate OSA and could have serious health consequences. In this context the management of the perioperative period, from anesthesia through the surgery itself and into the postoperative period, is more problematic for patients with sleep disordered breathing than for others. There is prolific literature in this area although large randomized trials are few due to the high sample size needed and possible ethical difficultie...
Source: Sleep Medicine Reviews - October 25, 2017 Category: Sleep Medicine Authors: Renaud Tamisier, Fanny Fabre, Fergal O'Donoghue, Patrick L évy, Jean-François Payen, Jean-Louis Pépin Tags: Clinical Review Source Type: research
