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Is there a role for switching antidepressants in treatment‐resistant depression?
Abstract This extract has been taken from Treatment‐resistant Depression By Siegfried Kasper and Stuart Montgomery (eds) Wiley‐Blackwell 2013 (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 8, 2013 Category: Neurology Authors: Stuart Montgomery Tags: Book extract Source Type: research

A radio phone‐in programme for mental health education and promotion
Abstract There is evidence that mass‐media campaigns can educate the public, influence health behaviour and may reduce stigma. In this article, the authors describe how they initiated a new local radio phone‐in programme covering different mental health problems and evaluated the benefits to members of the public who called the programme. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 8, 2013 Category: Neurology Authors: Richard Laugharne, Rohit Shankar, Rosie Dunkley, Sarah Fisher, Jonathan Barnett Tags: Original research Source Type: research

Negative symptoms in schizophrenia: meeting the challenge
Discussion, chaired by Progress publisher Tim Dean, the participants consider issues and solutions around the management of negative symptoms in schizophrenia, as well as developments for the future. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 8, 2013 Category: Neurology Authors: Allan Young, Rozmin Halari, Richard Gray Tags: Expert Panel Discussion Source Type: research

Improving schizophrenia care: kindness and competence are key
Abstract At the 12th Latest Advances in Psychiatry Symposium in March, Professor Sir Robin Murray provided colleagues with a synthesis of what he has learnt, observed and experienced in relation to schizophrenia in a Keynote Lecture that offered some real pearls of wisdom to those trying to help people with this devastating illness. Steve Titmarsh was among those privileged to listen. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 8, 2013 Category: Neurology Authors: Steve Titmarsh Tags: Keynote Lecture Source Type: research

DSM‐5: rewriting the ‘bible’
Abstract The 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5) was launched this May to much controversy. Medical writer Mark Greener discusses what the new edition means for psychiatrists and patients. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 8, 2013 Category: Neurology Authors: Mark Greener Tags: News review Source Type: research

An update on sleep disorders and their treatment
Abstract In the third of this series of updated reviews on the major psychiatric drug groups, produced in association with the College of Mental Health Pharmacy (CMHP; www.cmhp.org.uk), Michele Sie describes the main types of sleep disorder and their features, and provides an overview of their treatment. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 8, 2013 Category: Neurology Authors: Michele Sie Tags: Review Source Type: research

Chronic mania associated with left hippocampal atrophy
Abstract Abnormalities in the hippocampus have been implicated in the pathophysiology of bipolar disorder. Dr Chakraborty and Carmen Miramontes report an atypical presentation of bipolar disorder with chronic mania (lasting more than two years) in a patient with a history of head injury and evidence of left hippocampal atrophy on neuroimaging. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 8, 2013 Category: Neurology Authors: Nandini Chakraborty, Carmen Miramontes Tags: Case notes Source Type: research

Psychotropic discontinuation leading to an NMS‐like condition
Abstract Neuroleptic malignant syndrome (NMS) is a potentially life‐threatening condition, which can occur as a complication in patients taking antipsychotic medications. Drs Kurien and Vattakatuchery present the case of a patient with paranoid schizophrenia who developed NMS‐like symptoms following abrupt discontinuation of clozapine and venlafaxine. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 8, 2013 Category: Neurology Authors: Renjith Kurien, Joe John Vattakatuchery Tags: Case notes Source Type: research

Type 2 diabetes and cognitive impairment: a case for screening?
Abstract There have been many concerns raised regarding whole‐population screening for dementia. Targeting higher risk groups, such as those with type 2 diabetes, may be more clinically meaningful, argue Hannah Price and Andrew Larner. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 8, 2013 Category: Neurology Authors: Hannah L Price, Andrew J Larner Tags: Opinion Source Type: research

Managing sleep disorders in primary care
Abstract Our series of Commentaries from the Primary Care Neurology Society (P‐CNS) provide a primary care perspective on neurology articles featured in Progress in Neurology and Psychiatry. Here, Dr Shahid Dadabhoy discusses ‘An update on sleep disorders and their treatment’ (see page 15 of the September October 13 issue). (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - September 1, 2013 Category: Neurology Authors: Shahid Dadabhoy Tags: Comment Source Type: research

Digest
Abstract GPs should do more to identify adults who do little physical activity and provide brief advice to encourage them to be more active, a new NICE guideline states. Public Health Guideline No. 44: Physical Activity: Brief Advice for Adults in Primary Care (www.nice.org.uk/PH44) recognises the benefits of exercise for physical and mental wellbeing but points out that most people do not reach the official minimum recommended levels of activity. Inactive adults can be identified opportunistically or as part of the management of a long‐term condition. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - July 19, 2013 Category: Neurology Tags: Digest Source Type: research

Lifestyle‐related cardiovascular risk factors in patients with bipolar disorder
Abstract Studies suggest that people with bipolar affective disorder have higher rates of cardiovascular risk factors such as obesity, hypertension, diabetes, smoking and poor diet; however, there are few studies assessing specific risk factors in the UK population. Dr Brown and colleagues present the results of their study to evaluate lifestyle‐related cardiovascular risk factors in a community cohort of patients with bipolar disorder compared with the UK general population. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - July 19, 2013 Category: Neurology Authors: Steve Brown, Rupa Ramesh, Stephanie Newson, Rosie Isaacs Tags: Original research Source Type: research

Temporal lobe epilepsy with apparent suicidal gestures
Abstract Various ictal (during the seizure) behaviour patterns have been described in patients with epilepsy. Here, Drs Guruvaiah and Veerasamy describe unusual high‐risk ictal behaviours with the appearance of suicidal gestures in a patient who was subsequently given a diagnosis of temporal lobe epilepsy. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - July 19, 2013 Category: Neurology Authors: Latha Guruvaiah, Karthik Veerasamy Tags: Case notes Source Type: research

Beyond serotonin: new approaches to the management of depression
Abstract New antidepressant drugs with mechanisms of action other than through serotonin modulation are currently being developed, offering hope to patients with severe or treatment‐resistant depression. Mark Greener reports. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - July 19, 2013 Category: Neurology Authors: Mark Greener Tags: Research Source Type: research

Is dopamine still the key to treating schizophrenia?
Abstract Current antipsychotics are useful in treating schizophrenia but do not offer a complete solution to managing the illness. Recent research suggests that modifying targets upstream of dopamine receptor blockade may hold the key to an improved psychopharmacological approach, explained Dr Oliver Howes, Honorary Consultant Psychiatrist at the South London and Maudsley NHS Foundation Trust, speaking at a satellite symposium organised by Roche at the 12th Latest Advances in Psychiatry meeting in London in March. Steve Titmarsh reports. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - July 19, 2013 Category: Neurology Authors: Steve Titmarsh Tags: Satellite symposium Source Type: research