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A complex case of bipolar disorder responding to combined drug therapy
Abstract The aetiology of bipolar affective disorder is complex and can involve genetic, environmental, biochemical and organic factors. Here, Dr Kamlana describes a puzzling case of bipolar disorder in a patient with brain scan abnormalities, who responded well to combined treatment with mood stabilisers, an atypical antipsychotic and an SSRI together with a programme of rehabilitation. Copyright © 2014 John Wiley & Sons (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - February 11, 2014 Category: Neurology Authors: Sikandar Kamlana Tags: Case notes Source Type: research

Post‐stroke mania: a rare but treatable presentation
Abstract Mania occurring for the first time in later life is uncommon; however, it can rarely occur as a consequence of stroke. Here, the authors present the case of an elderly man who developed secondary mania shortly following a haemorrhagic stroke, and who responded well to treatment with olanzapine. Copyright © 2014 John Wiley & Sons (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - February 11, 2014 Category: Neurology Authors: Rajdeep Routh, Andrew Hill Tags: Case notes Source Type: research

Reducing medicines administration errors on dementia units
Abstract Dr Dawson describes her audit cycle carried out on two NHS dementia assessment units to assess the frequency of drug administration errors and the subsequent improvements made following simple interventions, including training sessions for nursing staff, clear coding of medication and encouraging the reporting of empty boxes as medication errors. Copyright © 2014 John Wiley & Sons (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - February 11, 2014 Category: Neurology Authors: Elizabeth Dawson Tags: Audit Source Type: research

Beneath the surface: dermatology and psychiatry
Abstract The impact that dermatological and psychiatric conditions have on each other is significant and complex, as Mark Greener discovered at the 22nd Congress of the European Association of Dermatology and Venereology (EADV) held in Istanbul in October 2013. Copyright © 2014 John Wiley & Sons (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - February 11, 2014 Category: Neurology Authors: Mark Greener Tags: News review Source Type: research

Diagnosis and management of myasthenia gravis
Abstract Myasthenia gravis is the most common primary disorder of neuromuscular transmission and one of the most treatable neurological disorders. In this review, Dr Sathasivam examines the epidemiology, presentation, aetiology, diagnosis and treatment of myasthenia gravis. Copyright © 2014 John Wiley & Sons (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - February 11, 2014 Category: Neurology Authors: Sivakumar Sathasivam Tags: Review Source Type: research

13th Latest Advances in Psychiatry: Biopsychosocial Approaches to Psychiatry
Abstract The 13th Latest Advances in Psychiatry Symposium, which will be held on the 12th March 2014 at the Royal College of Physicians in London, promises an impressive line‐up of speakers. Copyright © 2014 John Wiley & Sons (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - January 1, 2014 Category: Neurology Authors: Katherine Laight Tags: Comment Source Type: research

Digest
Abstract Parkinson's disease research Lundbeck has announced a partnership with the Michael J Fox Foundation to pursue promising projects that may lead to novel treatments for Parkinson's disease. The charity is providing about $1 million to support the development of two projects. The first is a therapeutic antibody binding to alpha‐synuclein protein; animal models suggest that this may slow disease progression. The second project is novel research to develop a drug targeted at an orphan Gprotein coupled receptor not associated with dopamine function. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - December 4, 2013 Category: Neurology Tags: Digest Source Type: research

Closing the diagnosis gap and improving care: the primary care memory clinic
Abstract Early diagnosis of dementia is vital for optimum care but diagnosis rates remain patchy across the UK. Dr Benbow and colleagues describe their innovative primary care memory clinic model in Gnosall, Staffordshire, and the benefits it has brought in terms of increasing diagnosis, improved patient care and cost savings. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - December 4, 2013 Category: Neurology Authors: Susan Mary Benbow, David Jolley, Ian Charles Greaves, Elaine Walker Tags: Multidisciplinary care Source Type: research

Review of the choice and use of antidepressant drugs
Abstract As part of our updated series of articles on the major psychiatric drug groups, produced in association with the College of Mental Health Pharmacy (www.cmhp.org.uk), Stephen Bleakley describes the use of antidepressants through a review of the most recent clinical literature. Pharmacology, interactions and side‐effects as well as drug choice and information to give to patients are discussed. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - December 4, 2013 Category: Neurology Authors: Stephen Bleakley Tags: Review Source Type: research

Neurology and psychiatry: ethics in the dock
Abstract The practice of neurology and psychiatry has always raised ethical dilemmas and this is still the case today with readily available genetic data and emerging drug treatments. Mark Greener discusses the ethical challenges that neurologists and psychiatrists currently face. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - December 4, 2013 Category: Neurology Authors: Mark Greener Tags: News Review Source Type: research

A personal approach to treatment is the key to advances in psychiatry
Abstract The search for the means to identify patients most likely to respond to specific treatments is the ultimate goal in many areas of medicine, and psychiatry is no exception. Delegates at the Latest Advances in Psychiatry symposium held in London in March heard about work within the fields of dementia, depression and addiction that may bring that goal closer to a reality. Steve Titmarsh reports. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - December 4, 2013 Category: Neurology Authors: Steve Titmarsh Tags: Conference Source Type: research

Sleep disorders and their treatment
(Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - December 4, 2013 Category: Neurology Authors: Kirstie Anderson, Michele Sie Tags: Letter Source Type: research

Use of asenapine in a case of treatment‐resistant bipolar disorder
Abstract Effective management of acute bipolar mania can be challenging, particularly in patients with comorbid substance use. Here, the authors describe the case of an acutely manic 37‐year‐old man with treatment‐resistant bipolar affective disorder and comorbid cannabis dependency, who responded well to treatment with asenapine, enabling him to be discharged back to the community psychiatric team. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - December 4, 2013 Category: Neurology Authors: Sarabjeet Kohli, Vinod Singh Tags: Case notes Source Type: research

Improving diagnosis and management of dementia in primary care
Abstract Our series of Commentaries from the Primary Care Neurology Society (P‐CNS) provide a primary care perspective on neurology articles featured in Progress in Neurology and Psychiatry. Here, Dr Jill Rasmussen discusses ‘Closing the diagnosis gap and improving care: the primary care memory clinic’ (see page 27). (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - November 1, 2013 Category: Neurology Authors: Jill Rasmussen Tags: Comment Source Type: research

Digest
Abstract The National Institute for Health Research (NIHR) has created a website to publicise its support for dementia research. Intended for the public, www.FocusOnDementia.nihr.ac.uk includes information about dementia and an overview of research written by Alistair Burns, National Clinical Director for Dementia for NHS England. A section explaining clinical trials aims to promote public participation in research and contributions to the work of the NIHR. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - October 8, 2013 Category: Neurology Tags: Digest Source Type: research