NICE multiple sclerosis quality standard
NICE quality standards should be viewed as a valuable resource to help guide those planning and delivering care to provide high‐quality services for patients. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 30, 2016 Category: Neurology Authors: Tarek A‐Z.K. Gaber, Mary Brown Tags: Comment Source Type: research

Population‐based screening for dementia: a role for 6CIT?
(Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 6, 2016 Category: Neurology Authors: Emma Phillips Tags: Letter Source Type: research

Pharmacological management of epilepsy
There have been significant advances in the management of epilepsy since the appearance of bromide in 1857. In the last decade, many new drugs have been developed and general understanding of the condition has improved. Here, Pharmacist Epilepsy Practitioner, Carole Brown, considers the current choice of antiepileptic drugs (AEDs), mode of action, newer AEDS, when to start treatment, epilepsy guidelines, adverse effects of AEDs, generic substitution, therapeutic drug monitoring, driving, contraception and bone health. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 6, 2016 Category: Neurology Authors: Carole Brown Tags: Review Source Type: research

Cognitive screening instruments for the diagnosis of mild cognitive impairment
Mild cognitive impairment (MCI) may represent an early, and potentially treatable, phase of dementing disorders. Its correct clinical identification is therefore of paramount importance. Here, Dr Larner analyses data from a selection of short cognitive screening instruments (CSIs) employed in a secondary care setting to measure various parameters for diagnosis of MCI and to establish whether any of the instruments have superior diagnostic utility. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 6, 2016 Category: Neurology Authors: Andrew J Larner Tags: Original research Source Type: research

Neuroimaging in dementia: an update for the general clinician
Structural neuroimaging is a fundamental part of a routine dementia assessment to rule out treatable causes of cognitive impairment, and to support early, accurate dementia subtype diagnosis. Dr Rayment and colleagues discuss the different types of imaging and when they should be used, as well as analysing some typical imaging findings from common dementia subtypes. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 6, 2016 Category: Neurology Authors: Dane Rayment, Maya Biju, Rui Zheng, Tarun Kuruvilla Tags: Review Source Type: research

EMDR: a tale of two treatments
(Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 6, 2016 Category: Neurology Authors: Gary Davies‐Ebsworth Tags: Letter Source Type: research

Resolution of flashbacks of PTSD with propranolol: a case report
An individual suffering from post‐traumatic stress disorder (PTSD) can continue to re‐experience the traumatic incident, which can involve a sense of extreme fear. In this article, the authors describe the case of a 36‐year‐old gentleman in whom the use of propranolol for the management of these persistent PTSD symptoms proved beneficial and led to the resolution of his flashback symptoms following difficulty in initial management with multiple other first‐line treatment modalities. Propranolol is currently not licensed for use in PTSD. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 6, 2016 Category: Neurology Authors: Rahul Chandavarkar, Sukhjinder Sangha, Salwa Khalil Tags: Case Notes Source Type: research

Phenylketonuria in an adult with normal diet
Phenylketonuria (PKU) is a rare inborn error of metabolism. It is caused by the deficiency of phenylalanine hydroxylase, an enzyme which converts phenylalanine to tyrosine and can cause severe learning disability in children if untreated. Drs Balaji et al. describe a case of an adult female with phenylketonuria and schizophrenia who was non‐compliant with the PKU diet. The case raises questions about the management of this condition in adults. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - April 6, 2016 Category: Neurology Authors: Kanmani Balaji, Manoj Narayan, Sarah Bradbury, Dasari Michael Tags: Case notes Source Type: research

Diagnosing dementia: piecing the jigsaw together
Our commentaries from the Primary Care Neurology Society (P‐CNS) provide a primary care perspective on the neurology articles in Progress. Here, Drs Benbow, Greaves and Jolley consider ‘Neuroimaging in dementia: an update for the general clinician’ (see p16). (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - February 29, 2016 Category: Neurology Authors: Susan M. Benbow, Ian Greaves, David Jolley Tags: Comment Source Type: research

Southern Health NHS Foundation Trust: held to account for its failure
(Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - February 9, 2016 Category: Neurology Authors: Joy Ogden Tags: Short report Source Type: research

Depression and pain: the need for a new screening tool
There is a strong association between pain and depression, and the presence of pain negatively affects the recognition and treatment of depression. Here, Dr Cocksedge and colleagues' explore the neurobiology behind this relationship and propose a new screening tool to assess patients with either condition for the coexistence of the other, with the potential for significantly better diagnosis, referral and hence treatment. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - February 9, 2016 Category: Neurology Authors: Karen Cocksedge, Rohit Shankar, Chantal Simon Tags: Review Source Type: research

Clinicians' attitudes towards patient involvement in mental health research
Mental health studies often recruit a low number of participants and Welcome Trust data have shown that less than a third of the trials successfully achieved their recruitment targets within the time frame given. The authors at the Oxford Health NHS Foundation Trust surveyed community staff to analyse the barriers to mental health research studies but also to uncover strategies for the future, which have the potential to shift the balance towards better patient recruitment into research and ultimately to secure future care informed by robust evidence. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - February 9, 2016 Category: Neurology Authors: Juliet Carmichael, Thomas Misselbrook, Leah Marriner, Alexandra Forrest, Andrew Molodynski Tags: Original research Source Type: research

Multiple episodes of NMS: overlap with malignant catatonia
There is ongoing debate in the literature as to whether neuroleptic malignant syndrome (NMS) and malignant catatonia are distinct clinical entities or illnesses on the same spectrum. Here, Drs Hardy and Evans present a case which puts forward arguments for both sides of the debate and raises questions regarding further management of psychosis in patients who develop multiple episodes of NMS. (Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - February 9, 2016 Category: Neurology Authors: Kate Hardy, Robert Evans Tags: Case notes Source Type: research

Cigarettes and capacity: a case study in enforced smoking cessation
The antipsychotic agent clozapine is frequently used in patients with treatment‐resistant psychotic illnesses such as schizophrenia and schizoaffective disorder. It is well established that cigarette smoking reduces circulating levels of clozapine, thereby limiting its efficacy. Here, Dr Cooney et al. report the unprecedented step in applying to the Courts for a mandate through the Adults with Incapacity Act (Scotland) for a patient to follow an enforced smoking cessation program in the hope that this would improve her psychiatric symptoms. The authors illustrate how solutions to medical problems can be achieved by looki...
Source: Progress in Neurology and Psychiatry - February 9, 2016 Category: Neurology Authors: Gary Cooney, Douglas Murdie, Anthony Moffoot Tags: Case notes Source Type: research

Population‐based screening for dementia: controversy and current status
(Source: Progress in Neurology and Psychiatry)
Source: Progress in Neurology and Psychiatry - February 9, 2016 Category: Neurology Authors: Emma Philips, Anna Walters, Maya Biju, Tarun Kuruvilla Tags: Comment Source Type: research