Impacts of Tumor Location, Nature and Bone Destruction of Extremity Osteosarcoma on Selection of Limb Salvage Operative Procedure
ConclusionSelection of limb salvage operative protocol for extremity OS should rely on tumor location, nature and extent of bone destruction. Regardless of tumor site, mechanical reconstruction is indicated for tumors with high invasion scores (>8), whereas biological reconstruction is preferred for those with low invasion scores (≤8). Tumors sparing the epiphyseal line or plate are ideal candidates for articular preservation. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Yu Chen, Xiu‐chun Yu, Song‐feng Xu, Ming Xu, Ruo‐xian Song Tags: CLINICAL ARTICLE Source Type: research

Preliminary Application of Precision Genomic Medicine Detecting Gene Variation in Patients with Multifocal Osteosarcoma
ConclusionsEarly and radical surgery accompanied by appropriate chemotherapy is the optimal means of treating MFOS. These patients may benefit from precision genomic medicine. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Hao‐qiang Zhang, Ming‐hui Li, Peng Gao, Ping‐heng Lan, Bo Fan, Xin Xiao, Ya‐jie Lu, Guo‐jing Chen, Zhen Wang Tags: CLINICAL ARTICLE Source Type: research

Delay in Diagnosis and Its Effect on Clinical Outcome in High‐grade Sarcoma of Bone: A Referral Oncological Centre Study
ConclusionProlonged delay in diagnosis does not result in lower survival. Metastatic disease has a pronounced effect on survival. Aggressive tumor behavior results in shorter delays. Minimizing GP‐related delays could be achieved by adopting a lower threshold for obtaining plain radiographs at the pre‐hospital stage. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Louren M Goedhart, Jasper G Gerbers, Joris J W Ploegmakers, Paul C Jutte Tags: CLINICAL ARTICLE Source Type: research

Biological Reconstruction in Bone Sarcomas: Lessons from Three Decades of Experience
ConclusionsAllografts are a good option for reconstruction after removal of larger tumors. It is necessary to take into account the mechanisms of incorporation and the measures that can be taken to reduce complications. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Mikel San‐Julian, Blanca Vazquez‐Garcia Tags: CLINICAL ARTICLE Source Type: research

Advances in Bone‐targeted Drug Delivery Systems for Neoadjuvant Chemotherapy for Osteosarcoma
Targeted therapy for osteosarcoma includes organ, cell and molecular biological targeting; of these, organ targeting is the most mature. Bone‐targeted drug delivery systems are used to concentrate chemotherapeutic drugs in bone tissues, thus potentially resolving the problem of reaching the desired foci and minimizing the toxicity and adverse effects of neoadjuvant chemotherapy. Some progress has been made in bone‐targeted drug delivery systems for treatment of osteosarcoma; however, most are still at an experimental stage and there is a long transitional period to clinical application. Therefore, determining how to co...
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Cheng‐jun Li, Xiao‐zhou Liu, Lei Zhang, Long‐bang Chen, Xin Shi, Su‐jia Wu, Jian‐ning Zhao Tags: REVIEW ARTICLE Source Type: research

Surgery Combined with Radiotherapy to Treat Spinal Tumors: A Review of Published Reports
Spinal tumors result in high morbidity and a high rate of lower limb paralysis. Both surgical therapy and radiation therapy (RT) are used to treat spinal tumors; however, how best to combine these two therapies to maximize the benefits and minimize the risks is still being debated. It is also difficult to decide the optimal timing, course and dose of RT, especially in pregnant women and children. The aim of this review is to assist surgeons who are dealing with spinal tumors by providing comprehensive information about advanced techniques for administering RT with greater precision and safety, and about the impact of vario...
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Chong Bian, Nong Chen, Xi‐lei Li, Xiao‐gang Zhou, Hong Lin, Li‐bo Jiang, Wang‐mi Liu, Qian Chen, Jian Dong Tags: REVIEW ARTICLE Source Type: research

Issue Information
(Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - April 30, 2016 Category: Orthopaedics Tags: ISSUE INFORMATION Source Type: research

Treatment of Spinal Tuberculosis by Debridement, Interbody Fusion and Internal Fixation via Posterior Approach Only
Surgical treatment for spinal tuberculosis includes focal tuberculosis debridement, segmental stability reconstruction, neural decompression and kyphotic deformity correction. For the lesions mainly involved anterior and middle column of the spine, anterior operation of debridement and fusion with internal fixation has been becoming the most frequently used surgical technique for the spinal tuberculosis. However, high risk of structural damage might relate with anterior surgery, such as damage in lungs, heart, kidney, ureter and bowel, and the deformity correction is also limited. Due to the organs are in the front of spin...
Source: Orthopaedic Surgery - March 29, 2016 Category: Orthopaedics Authors: Ming‐xing Tang, Hong‐qi Zhang, Yu‐xiang Wang, Chao‐feng Guo, Jin‐yang Liu Tags: VIDEO OF ORTHOPAEDIC TECHNIQUE Source Type: research

Double Dislocation of Interphalangeal Joints Accompanied with Contralateral Shoulder Dislocation: A Case Report
We report a rare case of double dislocation of the interphalangeal joints accompanied with contralateral shoulder dislocation in an elderly man sustained after a fall which was treated successfully with closed reduction and early mobilization. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - March 29, 2016 Category: Orthopaedics Authors: Pradyumna Ramchandra Raval, Arpit Jariwala Tags: CASE REPORT Source Type: research

S2 Alar‐iliac Fixation: A Powerful Procedure for the Treatment of Kyphoscoliosis
The purpose of this study was to introduce a powerful technique for the treatment of kyphoscoliosis. There are currently multiple techniques for sacropelvic fixation, including trans‐iliac bars and iliac and iliosacral screws. Several studies have documented the use of these instrumentation techniques; however, a ubiquitous problematic issue concerns the need for separate incisions for the use of offset connectors, which add to surgical time and morbidity. Any additional dissection of the skin, subcutaneous tissue or muscle in this area is believed to increase the incidence of complications of wound healing. However, as ...
Source: Orthopaedic Surgery - March 29, 2016 Category: Orthopaedics Authors: Zhen Liu, Yong Qiu, Huang Yan, Zong‐shan Hu, Feng Zhu, Jun Qiao, Lei‐lei Xu, Bin Wang, Yang Yu, Bang‐ping Qian, Ze‐zhang Zhu Tags: SURGICAL TECHNIQUE Source Type: research

Clinical Significance of a Novel Knee Joint Stability Assessment System for Evaluating Anterior Cruciate Ligament Deficient Knees
Conclusions Opti_Knee (Innomotion) can detect abnormal kinematics in ACL deficient knees and thus provides an effective way of assisting the diagnosis of this condition and has potential for clinical application. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - March 29, 2016 Category: Orthopaedics Authors: Zi‐long Yao, Shao‐bai Wang, Yu Zhang, Wen‐han Huang, Hong‐yuan Shen, Li‐min Ma, Hua‐yang Huang, Hong Xia Tags: ORTHOPAEDIC TECHNIQUE Source Type: research

Effect of a New Annular Incision on Biomechanical Properties of the Intervertebral Disc
ConclusionThe novel oblique slit annular incision to the intervertebral disc showed a trend toward better biomechanical properties than the traditional transverse and longitudinal slit incisions. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - March 29, 2016 Category: Orthopaedics Authors: Ling‐jie Fu, Chang‐sheng Chen, You‐zhuan Xie, Jian‐wei Yang, Xiao‐jiang Sun, Pu Zhang Tags: SCIENTIFIC ARTICLE Source Type: research

Perioperative Period of a Hemophilia‐related Osteoarthropathy Therapeutic Regimen and Analysis of Complications
ConclusionsSurgical treatment is a safe and reliable choice for addressing complications including hemophilia‐related osteoarthropathy given the implementation of effective measures for treatment during the perioperative period. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - March 29, 2016 Category: Orthopaedics Authors: Ye Li, Xi‐sheng Weng, Jin Lin, Jin Jin, Wen‐wei Qian, Bao‐zhong Zhang, Peng Gao, Ji‐liang Zhai Tags: CLINICAL ARTICLE Source Type: research

Open Patellar Tendon Tenotomy and Debridement Combined with Suture‐bridging Double‐row Technique for Severe Patellar Tendinopathy
ConclusionsAll study patients achieved good or excellent outcomes. No patellar tendon rupture or suture fixation failure occurred during follow‐up. Suture‐bridging double‐row fixation is a simple and reliable method that not only improves patients’ clinical symptoms, but also restores knee joint function. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - March 29, 2016 Category: Orthopaedics Authors: Bo Zhang, Tie‐bing Qu, Jiang Pan, Zhi‐wei Wang, Xiao‐dong Zhang, Shi‐xiang Ren, Liang Wen, Tong Chen, De‐si Ma, Yuan Lin, Cheng‐Kung Cheng Tags: CLINICAL ARTICLE Source Type: research

Mini‐invasive Transforaminal Lumbar Interbody Fusion through Wiltse Approach to Treating Lumbar Spondylolytic Spondylolisthesis
ConclusionTLIF via both approaches has satisfactory clinical efficacy. TLIF through the Wiltse approach significantly reduces the damage of multifidus and postoperative incidence of chronic LBP. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - March 29, 2016 Category: Orthopaedics Authors: Chao Zhou, Yong‐hao Tian, Yan‐ping Zheng, Xin‐yu Liu, Hu‐hu Wang Tags: CLINICAL ARTICLE Source Type: research