Direct Tubular Lumbar Microdiscectomy for Far Lateral Disc Herniation: A Modified Approach
ConclusionsA modified direct tubular approach is safe and effective for treating far lateral lumbar disc herniation. Our early results suggest that this approach helps safeguard adequate decompression and reduce the risk of postoperative dysesthesia. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - September 13, 2016 Category: Orthopaedics Authors: Timothy L T Siu, Kainu Lin Tags: CLINICAL ARTICLE Source Type: research

Analgesic Efficacy of Adductor Canal Block in Total Knee Arthroplasty: A Meta ‐analysis and Systematic Review
The aim of this meta‐analysis and systematic review of randomized controlled trials (RCTs) was to evaluate the efficacy and safety of adductor canal block (ACB) for early postoperative pain management in patients undergoing total knee arthroplasty (TKA). Relevant manuscripts comparing ACB with saline or femoral nerve block (FNB) in TKA patients were searched for in the databases of PubMed, EMBASE, and Cochrane library. The outcomes assessed included cumulative analgesic consumption, pain at rest or during movement, ability to ambulate, quadriceps strength, and complications (nausea, vomiting or sedation). For continuous ...
Source: Orthopaedic Surgery - September 13, 2016 Category: Orthopaedics Authors: Xu Jiang, Qian ‐qian Wang, Cheng‐ai Wu, Wei Tian Tags: REVIEW ARTICLE Source Type: research

Efficiency and Safety of Intravenous Tranexamic Acid in Simultaneous Bilateral Total Knee Arthroplasty: A Systematic Review and Meta ‐analysis
The objective of this systematic review and meta‐analysis was to evaluate the efficacy and safety of i.v. tranexamic acid (TXA) in simultaneous bilateral total knee arthroplasty (TKA). Potentially relevant published reports were identified from the following electronic databases: Medline, PubMed, Embase, ScienceDirect and Cochrane Library. RevMan v5.3was used to pool data. Two randomized controlled trials and four case‐control studies met the inclusion criteria. The current meta‐analysis identified significant differences between TXA group and control groups in terms of postoperative hemoglobin concentration (P < ...
Source: Orthopaedic Surgery - September 13, 2016 Category: Orthopaedics Authors: Xuan Jiang, Xin ‐long Ma, Jian‐xiong Ma Tags: REVIEW ARTICLE Source Type: research

Advances in Spinal Interbody Cages
Since the late 1980s, spinal interbody cages (ICs) have been used to aid bone fusion in a variety of spinal disorders. Utilized to restore intervertebral height, enable bone graft containment for arthrodesis, and restore anterior column biomechanical stability, ICs have since evolved to become a highly successful means of achieving fusion, being associated with less postoperative pain, shorter hospital stay, fewer complications and higher rates of fusion when than bone graft only spinal fusion. IC design and materials have changed considerably over the past two decades. The threaded titanium‐alloy cylindrical screw cages...
Source: Orthopaedic Surgery - September 13, 2016 Category: Orthopaedics Authors: Sukrit Jain, Adam E M Eltorai, Roy Ruttiman, Alan H Daniels Tags: REVIEW ARTICLE Source Type: research

Evolution of Design of Interbody Cages for Anterior Lumbar Interbody Fusion
This article therefore aims to provide an overview of the historical basis for the anterior approach, evolution in design of ALIF cage implants and potential future research directions. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - September 13, 2016 Category: Orthopaedics Authors: Kevin Phan, Ralph J Mobbs Tags: REVIEW ARTICLE Source Type: research

Consensus on Surgical Management of Myeloma Bone Disease
Myeloma bone disease (MBD), the skeletal lesions caused by multiple myeloma, is also known as skeletal related events and includes bone pain, osteoporosis, pathological fractures, osteolytic bone lesions, spinal instability, spinal cord and nerve root compression and extramedullary plasmacytoma. It is now generally accepted that patients with these complications usually require surgical management and that such treatment is safe and effective. The aims of surgical interventions are to alleviate pain, improve quality of life, treat potential or existing pathological fractures, decompress the spinal cord and nerve roots, and...
Source: Orthopaedic Surgery - September 13, 2016 Category: Orthopaedics Tags: CONSENSUS Source Type: research

Issue Information
(Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 31, 2016 Category: Orthopaedics Tags: ISSUE INFORMATION Source Type: research

Expression of Matrix Metalloproteinase ‐9 and CD34 in Giant Cell Tumor of Bone
ConclusionExpression of CD34 and MMP‐9 accurately predicts clinical behavior detection and prognosis of GCTBs. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Xing Zhou, Xiao ‐zhou Liu, Gen‐tao Fan, Su‐jia Wu, Jian‐ning Zhao, Xin Shi Tags: CLINICAL ARTICLE Source Type: research

Open Surgery for Osteoid Osteoma with Three Dimensional C ‐arm Scan under the Guidance of Computer Navigation
ConclusionsThe niduses of osteoid osteomas can be eradicated by open surgery with 3‐D C‐arm scan under the guidance of computer navigation with minimal damage to bone structure and a high rate of pathologically confirmed diagnoses. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Nong Lin, Zhao ‐ming Ye, Hao Qu, Xiao‐bo Yan, Wei‐bo Pan, Xin Huang, Meng Liu Tags: CLINICAL ARTICLE Source Type: research

Transnasal Endoscopic Biopsy Approach to Atlas Tumor with X ‐ray Assisted and Related Radiographic Measure
ConclusionsAn endoscopic transnasal approach enables biopsy and diagnosis of tumors in the anterior arch of the atlas. Relevant measurements were obtained by assessing CT scans of 50 volunteers to assist operators to determine the effective and safe range for transnasal atlas biopsy. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Zhen ‐feng Li, Xian‐hao Shao, Li‐qiang Zhang, Zhi‐ping Yang, Xin Li, Qiang Yang, Jian‐min Li Tags: CLINICAL ARTICLE Source Type: research

En Bloc Resection of Primary Malignant Bone Tumor in the Cervical Spine Based on 3 ‐Dimensional Printing Technology
ConclusionThough technically challenging, it is feasible and safe to perform en bloc resection of cervical primary bone tumors. This is the most effective means of managing cervical spine tumors. Preoperative 3‐D printing modelling enables better anatomical understanding of the relationship between the tumor and cervical spine and can assist in planning the surgical procedure. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Jian ‐ru Xiao, Wen‐ding Huang, Xing‐hai Yang, Wang‐jun Yan, Dian‐wen Song, Hai‐feng Wei, Tie‐long Liu, Zhi‐peng Wu, Cheng Yang Tags: CLINICAL ARTICLE Source Type: research

Surgical Treatment of Sacral Neurogenic Tumor: A 10 ‐year Experience with 64 Cases
ConclusionsThe clinical characteristics of sacral neurogenic tumors make them easy to diagnose. The approach to resection should be determined by the location and size of the tumor. Patients with huge tumors may lose considerable blood intraoperatively and a have higher risk rate of postoperative complications. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Wei Sun, Xiao ‐jun Ma, Fan Zhang, Wei‐liang Miao, Chong‐ren Wang, Zheng‐dong Cai Tags: CLINICAL ARTICLE Source Type: research

Delay in Diagnosis and Its Effect on Clinical Outcome in High ‐grade Sarcoma of Bone: A Referral Oncological Centre Study
ConclusionProlonged delay in diagnosis does not result in lower survival. Metastatic disease has a pronounced effect on survival. Aggressive tumor behavior results in shorter delays. Minimizing GP‐related delays could be achieved by adopting a lower threshold for obtaining plain radiographs at the pre‐hospital stage. (Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Louren M Goedhart, Jasper G Gerbers, Joris J W Ploegmakers, Paul C Jutte Tags: CLINICAL ARTICLE Source Type: research

Advances in Bone ‐targeted Drug Delivery Systems for Neoadjuvant Chemotherapy for Osteosarcoma
Targeted therapy for osteosarcoma includes organ, cell and molecular biological targeting; of these, organ targeting is the most mature. Bone‐targeted drug delivery systems are used to concentrate chemotherapeutic drugs in bone tissues, thus potentially resolving the problem of reaching the desired foci and minimizing the toxicity and adverse effects of neoadjuvant chemotherapy. Some progress has been made in bone‐targeted drug delivery systems for treatment of osteosarcoma; however, most are still at an experimental stage and there is a long transitional period to clinical application. Therefore, determining how to co...
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Authors: Cheng ‐jun Li, Xiao‐zhou Liu, Lei Zhang, Long‐bang Chen, Xin Shi, Su‐jia Wu, Jian‐ning Zhao Tags: REVIEW ARTICLE Source Type: research

Erratum
(Source: Orthopaedic Surgery)
Source: Orthopaedic Surgery - July 6, 2016 Category: Orthopaedics Tags: ERRATUM Source Type: research