Structure ‐function aspects of the Porphyromonas gingivalis tyrosine kinase Ptk1
This article is protected by copyright. All rights reserved. (Source: Oral Microbiology and Immunology)
Source: Oral Microbiology and Immunology - July 31, 2016 Category: Microbiology Authors: Chengcheng Liu, Daniel P. Miller, Yan Wang, Michael Merchant, Richard J. Lamont Tags: Original Article Source Type: research
Tannerella forsythia GroEL induces inflammatory bone resorption and synergizes with IL ‐17
This study investigated the potential of T. forsythia GroEL to induce inflammatory bone resorption and examined the cooperative effect of IL‐17 and T. forsythia GroEL on inflammatory responses. Human gingival fibroblasts (HGFs) and periodontal ligament (PDL) fibroblasts were stimulated with T. forsythia GroEL and/or IL‐17. Gene expression of IL‐6, IL‐8, and cyclooxygenase (COX)‐2 and concentrations of IL‐6, IL‐8, and prostaglandin E2 (PGE2) were measured by real‐time reverse transcription polymerase chain reaction and enzyme‐linked immunosorbent assays, respectively. After stimulation of MG63 cells with T...
Source: Oral Microbiology and Immunology - July 31, 2016 Category: Microbiology Authors: Young ‐Jung Jung, Yu‐Jung Choi, Sun‐Jin An, Hae‐Ri Lee, Hye‐Kyoung Jun, Bong‐Kyu Choi Tags: Original Article Source Type: research
The Road Less Traveled – Defining molecular commensalism with Streptococcus sanguinis
This article is protected by copyright. All rights reserved. (Source: Oral Microbiology and Immunology)
Source: Oral Microbiology and Immunology - July 31, 2016 Category: Microbiology Authors: Jens Kreth, Rodrigo A. Giacaman, Rahul Raghavan, Justin Merritt Tags: Invited Review Source Type: research
Nucleases from Prevotella intermedia can Degrade Neutrophil Extracellular Traps
This article is protected by copyright. All rights reserved. (Source: Oral Microbiology and Immunology)
Source: Oral Microbiology and Immunology - July 31, 2016 Category: Microbiology Authors: Midori Doke, Haruka Fukamachi, Hirobumi Morisaki, Takafumi Arimoto, Hideo Kataoka, Hirotaka Kuwata Tags: Original Article Source Type: research
Caveolin ‐1 serves as a negative effector in senescent human gingival fibroblasts during Fusobacterium nucleatum infection
Summary
It is well established that aging is associated with increased susceptibility to infectious diseases. Fusobacterium nucleatum is a well‐known bacterial species that plays a central bridging role between early and late colonizers in the human oral cavity. Further, the ability of F. nucleatum to invade gingival fibroblasts (GFs) is critical to the development of periodontal diseases. However, the mechanisms underlying the age‐related infection of GFs by F. nucleatum remain unknown. We used young (fourth passage) and senescent (22nd passage) GFs to investigate the mechanisms of F. nucleatum infection in aged GF...
Source: Oral Microbiology and Immunology - July 30, 2016 Category: Microbiology Authors: S.H. Ahn, S. ‐H. Cho, J.‐E. Song, S. Kim, S.S. Oh, S. Jung, K.A. Cho, T.‐H. Lee Tags: Original Article Source Type: research
Activation of the TREM ‐1 pathway in human monocytes by periodontal pathogens and oral commensal bacteria
This article is protected by copyright. All rights reserved. (Source: Oral Microbiology and Immunology)
Source: Oral Microbiology and Immunology - July 24, 2016 Category: Microbiology Authors: Mrudula Varanat, Elaine M. Haase, Jason G. Kay, Frank A. Scannapieco Tags: Original Article Source Type: research
Acid ‐adaptive mechanisms of Streptococcus mutans–the more we know, the more we don't
(Source: Oral Microbiology and Immunology)
Source: Oral Microbiology and Immunology - June 20, 2016 Category: Microbiology Authors: J.L. Baker, R.C. Faustoferri, R.G. Quivey Tags: Review Source Type: research
Acid‐adaptive mechanisms of Streptococcus mutans–the more we know, the more we don't
(Source: Oral Microbiology and Immunology)
Source: Oral Microbiology and Immunology - June 20, 2016 Category: Microbiology Authors: J.L. Baker, R.C. Faustoferri, R.G. Quivey Tags: Review Source Type: research
FISHing for gutta ‐percha‐adhered biofilms in purulent post‐treatment apical periodontitis
This study investigated the possibility to depict individual taxa in clinically relevant biofilms using fluorescent in situ hybridization (FISH). Gutta‐percha samples were collected from the apical aspect of root canals associated with a chronic apical abscess (test samples, n = 8). Corresponding control samples were obtained from previously filled root canals with apparently normal periapical tissues (n = 3). The transport medium was investigated for detached biofilm fragments using FISH staining and conventional epifluorescence microscopy. Gutta‐percha samples were stained by multiplex FISH, and inspected using confo...
Source: Oral Microbiology and Immunology - June 9, 2016 Category: Microbiology Authors: M. Zehnder, D. ‐K. Rechenberg, T. Thurnheer, H. Lüthi‐Schaller, G.N. Belibasakis Tags: Original Article Source Type: research
Immunologic Environment Influences Macrophage Response to Porphyromonas gingivalis
This article is protected by copyright. All rights reserved. (Source: Oral Microbiology and Immunology)
Source: Oral Microbiology and Immunology - May 31, 2016 Category: Microbiology Authors: George Papadopoulos, Yazdani B. Shaik‐Dasthagirisaheb, Nasi Huang, Gregory A. Viglianti, Andrew J. Henderson, Alpdogan Kantarci, Frank III C. Gibson Tags: Original Article Source Type: research
Caveolin 1 serves as a negative effector in senescent human gingival fibroblasts during Fusobacterium nucleatum infection
This article is protected by copyright. All rights reserved. (Source: Oral Microbiology and Immunology)
Source: Oral Microbiology and Immunology - May 31, 2016 Category: Microbiology Authors: Sun Hee Ahn, Sung‐Hyun Cho, Ji‐Eun Song, Suhee Kim, Seung Su Oh, Seunggon Jung, Kyung A Cho, Tae‐Hoon Lee Tags: Original Article Source Type: research
FISHing for gutta‐percha‐adhered biofilms in purulent post‐treatment apical periodontitis
This study investigated the possibility to depict individual taxa in clinically relevant biofilms using fluorescent in situ hybridization (FISH). Gutta‐percha samples were collected from the apical aspect of root canals associated with a chronic apical abscess (test samples, n = 8). Corresponding control samples were obtained from previously filled root canals with apparently normal periapical tissues (n = 3). The transport medium was investigated for detached biofilm fragments using FISH staining and conventional epifluorescence microscopy. Gutta‐percha samples were stained by multiplex FISH, and inspected using confo...
Source: Oral Microbiology and Immunology - May 31, 2016 Category: Microbiology Authors: M. Zehnder, D.‐K. Rechenberg, T. Thurnheer, H. Lüthi‐Schaller, G.N. Belibasakis Tags: Original Article Source Type: research
Global TLR2 and 4 Deficiency in mice impacts Bone resorption, Inflammatory Markers and Atherosclerosis to Polymicrobial Infection
This study supports a role for TLR2 and TLR4 in PD and atherosclerosis, corroborating an intricate association between two inflammatory diseases.
This article is protected by copyright. All rights reserved. (Source: Oral Microbiology and Immunology)
Source: Oral Microbiology and Immunology - May 25, 2016 Category: Microbiology Authors: Sasanka S. Chukkapalli, Irina M. Velsko, Mercedes F. Rivera‐Kweh, Hannu Larjava, Alexandra R. Lucas, Lakshmyya Kesavalu Tags: Original Article Source Type: research
Effect of salivary agglutination on oral streptococcal clearance by human polymorphonuclear neutrophil granulocytes
This article is protected by copyright. All rights reserved. (Source: Oral Microbiology and Immunology)
Source: Oral Microbiology and Immunology - May 19, 2016 Category: Microbiology Authors: Andreas Itzek, Zhiyun Chen, Justin Merritt, Jens Kreth Tags: Original Article Source Type: research
Differential capacity for complement receptor ‐mediated immune evasion by Porphyromonas gingivalis depending on the type of innate leukocyte
Summary
The complement system plays a central role in immunity and inflammation, although certain pathogens can exploit complement to undermine protective immunity. In this context, the periodontal keystone pathogen Porphyromonas gingivalis was previously shown by our group to evade killing by neutrophils or macrophages through exploitation of complement C5a receptor 1 (C5aR1) and complement receptor 3 (CR3). Here, we examined whether P. gingivalis uses complement receptors to also subvert killing by dendritic cells. In line with earlier independent studies, intracellular viable P. gingivalis bacteria could be recovered ...
Source: Oral Microbiology and Immunology - May 17, 2016 Category: Microbiology Authors: G. Hajishengallis, J.L. Krauss, R. Jotwani, J.D. Lambris Tags: Original Article Source Type: research
