Corrections
Nature Biotechnology 35, 1124 (2017).
doi:10.1038/nbt1217-1124b (Source: Nature Biotechnology)
Source: Nature Biotechnology - December 8, 2017 Category: Biotechnology Tags: Correction Source Type: research
Activists bury India's GM mustard hopes
Nature Biotechnology 35, 1124 (2017).
doi:10.1038/nbt1217-1124a
Author: Killugudi Jayaraman (Source: Nature Biotechnology)
Source: Nature Biotechnology - December 8, 2017 Category: Biotechnology Authors: Killugudi Jayaraman Tags: News Source Type: research
The Broad and Johns Hopkins lure deep-pocketed investors
Nature Biotechnology 35, 1123 (2017).
doi:10.1038/nbt1217-1123
Author: Eva von Schaper (Source: Nature Biotechnology)
Source: Nature Biotechnology - December 8, 2017 Category: Biotechnology Authors: Eva von Schaper Tags: News Source Type: research
Around the world in a month
Nature Biotechnology 35, 1122 (2017).
doi:10.1038/nbt1217-1122 (Source: Nature Biotechnology)
Source: Nature Biotechnology - December 8, 2017 Category: Biotechnology Tags: News Source Type: research
A new crop of microbe startups raises big bucks, takes on the establishment
Nature Biotechnology 35, 1120 (2017).
doi:10.1038/nbt1217-1120
Author: Emily Waltz (Source: Nature Biotechnology)
Source: Nature Biotechnology - December 8, 2017 Category: Biotechnology Authors: Emily Waltz Tags: News Source Type: research
California cracks down on stem cell cowboys
Nature Biotechnology 35, 1119 (2017).
doi:10.1038/nbt1217-1119
Author: Laura DeFrancesco (Source: Nature Biotechnology)
Source: Nature Biotechnology - December 8, 2017 Category: Biotechnology Authors: Laura DeFrancesco Tags: News Source Type: research
Amgen cholesterol antibody feud could kill key IP rule
Nature Biotechnology 35, 1118 (2017).
doi:10.1038/nbt1217-1118
Author: Mark Ratner (Source: Nature Biotechnology)
Source: Nature Biotechnology - December 8, 2017 Category: Biotechnology Authors: Mark Ratner Tags: News Source Type: research
Ablynx's nanobody fragments go places antibodies cannot
Nature Biotechnology 35, 1115 (2017).
doi:10.1038/nbt1217-1115
Author: Cormac Sheridan (Source: Nature Biotechnology)
Source: Nature Biotechnology - December 8, 2017 Category: Biotechnology Authors: Cormac Sheridan Tags: News Source Type: research
Methods, preprints and papers
Nature Biotechnology 35, 1113 (2017).
doi:10.1038/nbt.4044
This journal supports preprints as a means to rapidly share research, but discourages their use as stand-alone citations disclosing a new method integral to the key results in a paper. (Source: Nature Biotechnology)
Source: Nature Biotechnology - December 8, 2017 Category: Biotechnology Tags: Editorial Source Type: research
Global landscape of cell envelope protein complexes in Escherichia coli
Nature Biotechnology 36, 103 (2018).
doi:10.1038/nbt.4024
Authors: Mohan Babu, Cedoljub Bundalovic-Torma, Charles Calmettes, Sadhna Phanse, Qingzhou Zhang, Yue Jiang, Zoran Minic, Sunyoung Kim, Jitender Mehla, Alla Gagarinova, Irina Rodionova, Ashwani Kumar, Hongbo Guo, Olga Kagan, Oxana Pogoutse, Hiroyuki Aoki, Viktor Deineko, J Harry Caufield, Erik Holtzapple, Zhongge Zhang, Ake Vastermark, Yogee Pandya, Christine Chieh-lin Lai, Majida El Bakkouri, Yogesh Hooda, Megha Shah, Dan Burnside, Mohsen Hooshyar, James Vlasblom, Sessandra V Rajagopala, Ashkan Golshani, Stefan Wuchty, Jack F Greenblatt, Milton Saier, Peter...
Source: Nature Biotechnology - November 27, 2017 Category: Biotechnology Authors: Mohan Babu Cedoljub Bundalovic-Torma Charles Calmettes Sadhna Phanse Qingzhou Zhang Yue Jiang Zoran Minic Sunyoung Kim Jitender Mehla Alla Gagarinova Irina Rodionova Ashwani Kumar Hongbo Guo Olga Kagan Oxana Pogoutse Hiroyuki Aoki Viktor Deineko J Harry C Tags: Research Source Type: research
Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR – Cas9 genome-editing efficiency
We report the discovery of a genetically encoded inhibitor of 53BP1 that increases the efficiency of HDR-dependent genome editing in human and mouse cells. 53BP1 is a key regulator of DSB repair pathway choice in eukaryotic cells and functions to favor NHEJ over HDR by suppressing end resection, which is the rate-limiting step in the initiation of HDR. We screened an existing combinatorial library of engineered ubiquitin variants for inhibitors of 53BP1. Expression of one variant, named i53 (inhibitor of 53BP1), in human and mouse cells, blocked accumulation of 53BP1 at sites of DNA damage and improved gene targeting and c...
Source: Nature Biotechnology - November 27, 2017 Category: Biotechnology Authors: Marella D Canny Nathalie Moatti Leo C K Wan Am é lie Fradet-Turcotte Danielle Krasner Pedro A Mateos-Gomez Michal Zimmermann Alexandre Orthwein Yu-Chi Juang Wei Zhang Sylvie M Noordermeer Eduardo Seclen Marcus D Wilson Andrew Vorobyov Meagan Munro Andrea Tags: Research Source Type: research
Three-dimensional map of nonhematopoietic bone and bone-marrow cells and molecules
Nature Biotechnology 35, 1202 (2017).
doi:10.1038/nbt.4006
Authors: Daniel L Coutu, Konstantinos D Kokkaliaris, Leo Kunz & Timm Schroeder (Source: Nature Biotechnology)
Source: Nature Biotechnology - November 13, 2017 Category: Biotechnology Authors: Daniel L Coutu Konstantinos D Kokkaliaris Leo Kunz Timm Schroeder Tags: Research Source Type: research
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
Nature Biotechnology 35, 1179 (2017).
doi:10.1038/nbt.4005
Authors: Hao Yin, Chun-Qing Song, Sneha Suresh, Qiongqiong Wu, Stephen Walsh, Luke Hyunsik Rhym, Esther Mintzer, Mehmet Fatih Bolukbasi, Lihua Julie Zhu, Kevin Kauffman, Haiwei Mou, Alicia Oberholzer, Junmei Ding, Suet-Yan Kwan, Roman L Bogorad, Timofei Zatsepin, Victor Koteliansky, Scot A Wolfe, Wen Xue, Robert Langer & Daniel G Anderson (Source: Nature Biotechnology)
Source: Nature Biotechnology - November 13, 2017 Category: Biotechnology Authors: Hao Yin Chun-Qing Song Sneha Suresh Qiongqiong Wu Stephen Walsh Luke Hyunsik Rhym Esther Mintzer Mehmet Fatih Bolukbasi Lihua Julie Zhu Kevin Kauffman Haiwei Mou Alicia Oberholzer Junmei Ding Suet-Yan Kwan Roman L Bogorad Timofei Zatsepin Victor Kotelians Tags: Research Source Type: research
Accurate assembly of transcripts through phase-preserving graph decomposition
Nature Biotechnology 35, 1167 (2017).
doi:10.1038/nbt.4020
Authors: Mingfu Shao & Carl Kingsford (Source: Nature Biotechnology)
Source: Nature Biotechnology - November 13, 2017 Category: Biotechnology Authors: Mingfu Shao Carl Kingsford Tags: Research Source Type: research
People
Nature Biotechnology 35, 1112 (2017).
doi:10.1038/nbt.4014 (Source: Nature Biotechnology)
Source: Nature Biotechnology - November 9, 2017 Category: Biotechnology Tags: Careers and Recruitment Source Type: research
