Trump threatens then signs, a win for FDA, NIH
Nature Biotechnology 36, 383 (2018). doi:10.1038/nbt0518-383 (Source: Nature Biotechnology)
Source: Nature Biotechnology - May 7, 2018 Category: Biotechnology Tags: News Source Type: research

Patent challenges to antibody and gene-therapy firms on the rise
Nature Biotechnology 36, 382 (2018). doi:10.1038/nbt0518-382 Author: Charlotte Harrison (Source: Nature Biotechnology)
Source: Nature Biotechnology - May 7, 2018 Category: Biotechnology Authors: Charlotte Harrison Tags: News Source Type: research

Indian biotech sector readies for liftoff
Nature Biotechnology 36, 380 (2018). doi:10.1038/nbt0518-380b Author: Killugudi Jayaraman (Source: Nature Biotechnology)
Source: Nature Biotechnology - May 7, 2018 Category: Biotechnology Authors: Killugudi Jayaraman Tags: News Source Type: research

2020 African American genomes
Nature Biotechnology 36, 380 (2018). doi:10.1038/nbt0518-380a (Source: Nature Biotechnology)
Source: Nature Biotechnology - May 7, 2018 Category: Biotechnology Tags: News Source Type: research

Cytokine resurrection: engineered IL-2 ramps up immuno-oncology responses
Nature Biotechnology 36, 378 (2018). doi:10.1038/nbt0518-378 Author: Ken Garber (Source: Nature Biotechnology)
Source: Nature Biotechnology - May 7, 2018 Category: Biotechnology Authors: Ken Garber Tags: News Source Type: research

Allogene and Celularity move CAR-T therapy off the shelf
Nature Biotechnology 36, 375 (2018). doi:10.1038/nbt0518-375 Author: Cormac Sheridan (Source: Nature Biotechnology)
Source: Nature Biotechnology - May 7, 2018 Category: Biotechnology Authors: Cormac Sheridan Tags: News Source Type: research

Unleashing biotech's crouching tiger
Nature Biotechnology 36, 373 (2018). doi:10.1038/nbt.4149 With a massive expansion in healthcare coverage, biotech's next big boom could occur in India. But this revolution will not be globalized—it will be about serving national needs. (Source: Nature Biotechnology)
Source: Nature Biotechnology - May 7, 2018 Category: Biotechnology Tags: Editorial Source Type: research

Deep learning massively accelerates super-resolution localization microscopy
Nature Biotechnology 36, 460 (2018). doi:10.1038/nbt.4106 Authors: Wei Ouyang, Andrey Aristov, Mickaël Lelek, Xian Hao & Christophe Zimmer (Source: Nature Biotechnology)
Source: Nature Biotechnology - April 16, 2018 Category: Biotechnology Authors: Wei Ouyang Andrey Aristov Micka ë l Lelek Xian Hao Christophe Zimmer Tags: Research Source Type: research

An in vivo model of functional and vascularized human brain organoids
Nature Biotechnology 36, 432 (2018). doi:10.1038/nbt.4127 Authors: Abed AlFatah Mansour, J Tiago Gonçalves, Cooper W Bloyd, Hao Li, Sarah Fernandes, Daphne Quang, Stephen Johnston, Sarah L Parylak, Xin Jin & Fred H Gage (Source: Nature Biotechnology)
Source: Nature Biotechnology - April 16, 2018 Category: Biotechnology Authors: Abed AlFatah Mansour J Tiago Gon ç alves Cooper W Bloyd Hao Li Sarah Fernandes Daphne Quang Stephen Johnston Sarah L Parylak Xin Jin Fred H Gage Tags: Research Source Type: research

Fast, long-term, super-resolution imaging with Hessian structured illumination microscopy
Nature Biotechnology 36, 451 (2018). doi:10.1038/nbt.4115 Authors: Xiaoshuai Huang, Junchao Fan, Liuju Li, Haosen Liu, Runlong Wu, Yi Wu, Lisi Wei, Heng Mao, Amit Lal, Peng Xi, Liqiang Tang, Yunfeng Zhang, Yanmei Liu, Shan Tan & Liangyi Chen (Source: Nature Biotechnology)
Source: Nature Biotechnology - April 11, 2018 Category: Biotechnology Authors: Xiaoshuai Huang Junchao Fan Liuju Li Haosen Liu Runlong Wu Yi Wu Lisi Wei Heng Mao Amit Lal Peng Xi Liqiang Tang Yunfeng Zhang Yanmei Liu Shan Tan Liangyi Chen Tags: Research Source Type: research

Simultaneous lineage tracing and cell-type identification using CRISPR – Cas9-induced genetic scars
Nature Biotechnology 36, 469 (2018). doi:10.1038/nbt.4124 Authors: Bastiaan Spanjaard, Bo Hu, Nina Mitic, Pedro Olivares-Chauvet, Sharan Janjuha, Nikolay Ninov & Jan Philipp Junker A key goal of developmental biology is to understand how a single cell is transformed into a full-grown organism comprising many different cell types. Single-cell RNA-sequencing (scRNA-seq) is commonly used to identify cell types in a tissue or organ. However, organizing the resulting taxonomy of cell types into lineage trees to understand the developmental origin of cells remains challenging. Here we present LINNAEUS (lineage tracin...
Source: Nature Biotechnology - April 9, 2018 Category: Biotechnology Authors: Bastiaan Spanjaard Bo Hu Nina Mitic Pedro Olivares-Chauvet Sharan Janjuha Nikolay Ninov Jan Philipp Junker Tags: Research Source Type: research

Highly scalable generation of DNA methylation profiles in single cells
Nature Biotechnology 36, 428 (2018). doi:10.1038/nbt.4112 Authors: Ryan M Mulqueen, Dmitry Pokholok, Steven J Norberg, Kristof A Torkenczy, Andrew J Fields, Duanchen Sun, John R Sinnamon, Jay Shendure, Cole Trapnell, Brian J O'Roak, Zheng Xia, Frank J Steemers & Andrew C Adey (Source: Nature Biotechnology)
Source: Nature Biotechnology - April 9, 2018 Category: Biotechnology Authors: Ryan M Mulqueen Dmitry Pokholok Steven J Norberg Kristof A Torkenczy Andrew J Fields Duanchen Sun John R Sinnamon Jay Shendure Cole Trapnell Brian J O'Roak Zheng Xia Frank J Steemers Andrew C Adey Tags: Research Source Type: research

People
Nature Biotechnology 36, 372 (2018). doi:10.1038/nbt.4122 (Source: Nature Biotechnology)
Source: Nature Biotechnology - April 5, 2018 Category: Biotechnology Tags: Careers and Recruitment Source Type: research

Involving undergraduates in genomics research to narrow the education – research gap
Nature Biotechnology 36, 369 (2018). doi:10.1038/nbt.4113 Authors: Serghei Mangul, Lana S Martin & Eleazar Eskin Engaging undergraduates in computational tasks can improve genomic research laboratory productivity, benefiting both students and senior laboratory members. (Source: Nature Biotechnology)
Source: Nature Biotechnology - April 5, 2018 Category: Biotechnology Authors: Serghei Mangul Lana S Martin Eleazar Eskin Tags: Careers and Recruitment Source Type: research

Erratum: Visualizing detailed postdoctoral employment trends using a new career outcome taxonomy
Nature Biotechnology 36, 368 (2018). doi:10.1038/nbt0418-368e Authors: Hong Xu, Richard S T Gilliam, Shyamal D Peddada, Gregory M Buchold & Tammy R L Collins (Source: Nature Biotechnology)
Source: Nature Biotechnology - April 5, 2018 Category: Biotechnology Authors: Hong Xu Richard S T Gilliam Shyamal D Peddada Gregory M Buchold Tammy R L Collins Tags: Erratum Source Type: research