Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing

Nature Biotechnology 35, 1179 (2017).
doi:10.1038/nbt.4005

Authors: Hao Yin, Chun-Qing Song, Sneha Suresh, Qiongqiong Wu, Stephen Walsh, Luke Hyunsik Rhym, Esther Mintzer, Mehmet Fatih Bolukbasi, Lihua Julie Zhu, Kevin Kauffman, Haiwei Mou, Alicia Oberholzer, Junmei Ding, Suet-Yan Kwan, Roman L Bogorad, Timofei Zatsepin, Victor Koteliansky, Scot A Wolfe, Wen Xue, Robert Langer & Daniel G Anderson

Source: Nature Biotechnology - November 13, 2017 Category: Biotechnology Authors: Hao Yin Chun-Qing Song Sneha Suresh Qiongqiong Wu Stephen Walsh Luke Hyunsik Rhym Esther Mintzer Mehmet Fatih Bolukbasi Lihua Julie Zhu Kevin Kauffman Haiwei Mou Alicia Oberholzer Junmei Ding Suet-Yan Kwan Roman L Bogorad Timofei Zatsepin Victor Kotelians Tags: Research Source Type: research