Gas5 Exerts Tumor-suppressive Functions in Human Glioma Cells by Targeting miR-222
& Yixue Xue (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Xihe ZhaoPing WangJing LiuJian ZhengYunhui LiuJiajia ChenYixue Xue Source Type: research

Receptor Crosslinking: A General Method to Trigger Internalization and Lysosomal Targeting of Therapeutic Receptor:Ligand Complexes
p; Arwyn T Jones (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Paul R MoodyEdward J SayersJohannes P MagnussonCameron AlexanderPaola BorriPeter WatsonArwyn T Jones Source Type: research

Comparative Study of Liver Gene Transfer With AAV Vectors Based on Natural and Engineered AAV Capsids
o & James M Wilson (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Lili WangPeter BellSuryanarayan SomanathanQiang WangZhenning HeHongwei YuDeirdre McMenaminTamara GoodeRoberto CalcedoJames M Wilson Source Type: research

Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors
Srivastava & Guangping Gao (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Shaoyong LiChen LingLi ZhongMengxin LiQin SuRan HeQiushi TangDale L GreinerLeonard D ShultzMichael A BrehmTerence R FlotteChristian MuellerArun SrivastavaGuangping Gao Source Type: research

Cardiac Nerve Growth Factor Overexpression Induces Bone Marrow–derived Progenitor Cells Mobilization and Homing to the Infarcted Heart
Cardiac Nerve Growth Factor Overexpression Induces Bone Marrow–derived Progenitor Cells Mobilization and Homing to the Infarcted Heart Molecular Therapy 23, 1854 (December 2015). doi:10.1038/mt.2015.167 Authors: Marco Meloni, Daniela Cesselli, Andrea Caporali, Giuseppe Mangialardi, Elisa Avolio, Carlotta Reni, Orazio Fortunato, Stefania Martini, Paolo Madeddu, Marco Valgimigli, Evgeni Nikolaev, Leszek Kaczmarek, Gianni D Angelini, Antonio P Beltrami & Costanza Emanueli (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Marco MeloniDaniela CesselliAndrea CaporaliGiuseppe MangialardiElisa AvolioCarlotta ReniOrazio FortunatoStefania MartiniPaolo MadedduMarco ValgimigliEvgeni NikolaevLeszek KaczmarekGianni D AngeliniAntonio P BeltramiCostanza Emanueli Source Type: research

Long Noncoding RNA CUDR Regulates HULC and β-Catenin to Govern Human Liver Stem Cell Malignant Differentiation
Long Noncoding RNA CUDR Regulates HULC and β-Catenin to Govern Human Liver Stem Cell Malignant Differentiation Molecular Therapy 23, 1843 (December 2015). doi:10.1038/mt.2015.166 Authors: Xin Gui, Haiyan Li, Tianming Li, Hu Pu & Dongdong Lu (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Xin GuiHaiyan LiTianming LiHu PuDongdong Lu Source Type: research

Modeling Human Bone Marrow Failure Syndromes Using Pluripotent Stem Cells and Genome Engineering
Winkler (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Moonjung JungCynthia E DunbarThomas Winkler Source Type: research

E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal—Tailored Acceleration of AAV Evolution
E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal—Tailored Acceleration of AAV Evolution Molecular Therapy 23, 1819 (December 2015). doi:10.1038/mt.2015.173 Authors: Dirk Grimm & Sergei Zolotukhin (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Dirk GrimmSergei Zolotukhin Source Type: research

Antisense MicroRNA Therapeutics in Cardiovascular Disease: Quo Vadis?
Costa Martins (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Leonne E PhilippenEllen DirkxJan B M WitKoos BurggraafLeon J de WindtPaula A da Costa Martins Source Type: research

BEST1: the Best Target for Gene and Cell Therapies
en H Tsang (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Tingting YangSally JustusYao LiStephen H Tsang Source Type: research

Receptor Crosslinking in Drug Delivery: Detour to the Lysosome?
r Sami (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Manfred OgrisHaider Sami Source Type: research

Selecting the Best AAV Capsid for Human Studies
Molecular Therapy 23, 1800 (December 2015). doi:10.1038/mt.2015.206 Author: Mark A Kay (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Mark A Kay Source Type: research

Research Highlights
Molecular Therapy 23, 1799 (December 2015). doi:10.1038/mt.2015.204 (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Source Type: research

In This Issue
Molecular Therapy 23, 1798 (December 2015). doi:10.1038/mt.2015.203 (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Source Type: research

A New Era of Innovation for CAR T-cell Therapy
Molecular Therapy 23, 1795 (December 2015). doi:10.1038/mt.2015.205 Author: Robert M Frederickson (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Robert M Frederickson Source Type: research