Nanoparticle Delivered VEGF-A siRNA Enhances Photodynamic Therapy for Head and Neck Cancer Treatment
h-Chih Hsu (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: Rumwald Leo G LecarosLeaf HuangTsai-Chia LeeYih-Chih Hsu Source Type: research

Grapefruit-derived Nanovectors Delivering Therapeutic miR17 Through an Intranasal Route Inhibit Brain Tumor Progression
ler & Huang-Ge Zhang (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: Xiaoying ZhuangYun TengAbhilash SamykuttyJingyao MuZhongbin DengLifeng ZhangPengxiao CaoYuan RongJun YanDonald MillerHuang-Ge Zhang Source Type: research

Oral-tolerization Prevents Immune Responses and Improves Transgene Persistence Following Gene Transfer Mediated by Adeno-associated Viral Vector
Olivier Boyer & Sahil Adriouch (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: Romain HardetBenjamin ChevalierLéa DupatyYassine NaïmiGaëtan RiouLaurent DrouotLaetitia JeanAnna SalvettiOlivier BoyerSahil Adriouch Source Type: research

Host Anti-antibody Responses Following Adeno-associated Virus–mediated Delivery of Antibodies Against HIV and SIV in Rhesus Monkeys
Host Anti-antibody Responses Following Adeno-associated Virus–mediated Delivery of Antibodies Against HIV and SIV in Rhesus Monkeys Molecular Therapy 24, 76 (January 2016). doi:10.1038/mt.2015.191 Authors: José M Martinez-Navio, Sebastian P Fuchs, Sònia Pedreño-López, Eva G Rakasz, Guangping Gao & Ronald C Desrosiers (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: José M Martinez-NavioSebastian P FuchsSònia Pedreño-LópezEva G RakaszGuangping GaoRonald C Desrosiers Source Type: research

Myocardial Delivery of Lipidoid Nanoparticle Carrying modRNA Induces Rapid and Transient Expression
& Kevin D Costa (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: Irene C TurnbullAhmed A EltoukhyKenneth M FishMathieu NonnenmacherKiyotake IshikawaJiqiu ChenRoger J HajjarDaniel G AndersonKevin D Costa Source Type: research

Development of Patient-specific AAV Vectors After Neutralizing Antibody Selection for Enhanced Muscle Gene Transfer
& R Jude Samulski (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: Chengwen LiShuqing WuBlake AlbrightMatthew HirschWuping LiYu-Shan TsengMavis Agbandje-McKennaScott McPheeAravind AsokanR Jude Samulski Source Type: research

Syndecan 4 Mediates Nrf2-dependent Expansion of Bronchiolar Progenitors That Protect Against Lung Inflammation
wa & Masakazu Ichinose (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: Arif SantosoToshiaki KikuchiNaoki TodeTaizou HiranoRiyo KomatsuTriya DamayantiHozumi MotohashiMasayuki YamamotoTetsuhito KojimaToshimitsu UedeToshihiro NukiwaMasakazu Ichinose Source Type: research

Targeted Proapoptotic Peptides Depleting Adipose Stromal Cells Inhibit Tumor Growth
Mikhail G Kolonin (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: Alexes C DaquinagChieh TsengYan ZhangFelipe Amaya-ManzanaresFernando FlorezAli DadbinTao ZhangMikhail G Kolonin Source Type: research

Clinical Improvement of Alpha-mannosidosis Cat Following a Single Cisterna Magna Infusion of AAV1
John H Wolfe (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: Sea Young YoonJessica H BagelPatricia A O'DonnellCharles H ViteJohn H Wolfe Source Type: research

Gene Therapy Restores Hair Cell Stereocilia Morphology in Inner Ears of Deaf Whirler Mice
p; Lisa L Cunningham (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: Wade W ChienKevin IsgrigSoumen RoyInna A BelyantsevaMeghan C DrummondLindsey A MayTracy S FitzgeraldThomas B FriedmanLisa L Cunningham Source Type: research

Development of Novel Adenoviral Vectors to Overcome Challenges Observed With HAdV-5–based Constructs
Development of Novel Adenoviral Vectors to Overcome Challenges Observed With HAdV-5–based Constructs Molecular Therapy 24, 6 (January 2016). doi:10.1038/mt.2015.194 Authors: Julio Alonso-Padilla, Tibor Papp, Győző L Kaján, Mária Benkő, Menzo Havenga, Angelique Lemckert, Balázs Harrach & Andrew H Baker (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: Julio Alonso-PadillaTibor PappGyőző L KajánMária BenkőMenzo HavengaAngelique LemckertBalázs HarrachAndrew H Baker Source Type: research

Research Highlights
Molecular Therapy 24, 5 (January 2016). doi:10.1038/mt.2015.230 (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Source Type: research

In This Issue
Molecular Therapy 24, 4 (January 2016). doi:10.1038/mt.2015.229 (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Source Type: research

An ASGCT Perspective on the National Academies Genome Editing Summit
Molecular Therapy 24, 1 (January 2016). doi:10.1038/mt.2015.228 Author: Theodore Friedmann (Source: Molecular Therapy)
Source: Molecular Therapy - February 8, 2016 Category: Genetics & Stem Cells Authors: Theodore Friedmann Source Type: research

Inhibition of Aggregation of Mutant Huntingtin by Nucleic Acid Aptamers In Vitro and in a Yeast Model of Huntington’s Disease
Inhibition of Aggregation of Mutant Huntingtin by Nucleic Acid Aptamers In Vitro and in a Yeast Model of Huntington’s Disease Molecular Therapy 23, 1912 (December 2015). doi:10.1038/mt.2015.157 Authors: Rajeev K Chaudhary, Kinjal A Patel, Milan K Patel, Radha H Joshi & Ipsita Roy (Source: Molecular Therapy)
Source: Molecular Therapy - December 22, 2015 Category: Genetics & Stem Cells Authors: Rajeev K ChaudharyKinjal A PatelMilan K PatelRadha H JoshiIpsita Roy Source Type: research