Increased Valency of Conserved-mosaic Vaccines Enhances the Breadth and Depth of Epitope Recognition
p; Tomáš Hanke (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Sultan Abdul-JawadBeatrice OndondoAndy van HaterenAndrew GardnerTim ElliottBette KorberTomáš Hanke Source Type: research

Curcumin Micelles Remodel Tumor Microenvironment and Enhance Vaccine Activity in an Advanced Melanoma Model
g & Leaf Huang (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Yao LuLei MiaoYuhua WangZhenghong XuYi ZhaoYouqing ShenGuangya XiangLeaf Huang Source Type: research

Characterization and Functional Analysis of scFv-based Chimeric Antigen Receptors to Redirect T Cells to IL13Rα2-positive Glioma
Characterization and Functional Analysis of scFv-based Chimeric Antigen Receptors to Redirect T Cells to IL13Rα2-positive Glioma Molecular Therapy 24, 354 (February 2016). doi:10.1038/mt.2015.199 Authors: Giedre Krenciute, Simone Krebs, David Torres, Meng-Fen Wu, Hao Liu, Gianpietro Dotti, Xiao-Nan Li, Maciej S Lesniak, Irina V Balyasnikova & Stephen Gottschalk (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Giedre KrenciuteSimone KrebsDavid TorresMeng-Fen WuHao LiuGianpietro DottiXiao-Nan LiMaciej S LesniakIrina V BalyasnikovaStephen Gottschalk Source Type: research

Absence of WASp Enhances Hematopoietic and Megakaryocytic Differentiation in a Human Embryonic Stem Cell Model
Gregory, Michael C Holmes & Francisco Martin (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Miguel G ToscanoPilar MuñozAlmudena Sánchez-GilabertMarién CoboKarim BenabdellahPer AndersonVerónica Ramos-MejíaPedro J RealOlaf NethAgueda Molinos-QuintanaPhilip D GregoryMichael C HolmesFrancisco Martin Source Type: research

Glucocorticoid Cell Priming Enhances Transfection Outcomes in Adult Human Mesenchymal Stem Cells
K Pannier (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Abby M KellySarah A PlautzJanos ZempleniAngela K Pannier Source Type: research

PTH Induces Systemically Administered Mesenchymal Stem Cells to Migrate to and Regenerate Spine Injuries
t, Gadi Pelled, Hyun M Bae & Dan Gazit (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Dmitriy SheynGalina ShapiroWafa TawackoliDouk Soo JunYoungdo KohKyu Bok KangSusan SuXiaoyu DaShiran Ben-DavidMaxim BezEran YalonBen AntebiPablo AvalosTomer SternElazar ZelzerEdward M SchwarzZulma GazitGadi PelledHyun M BaeDan Gazit Source Type: research

Perfusion Pressure Is a Critical Determinant of the Intratumoral Extravasation of Oncolytic Viruses
tephen J Russell (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Amber MillerRebecca NaceCamilo Ayala-Breton CMichael SteeleKent BaileyKah Whye PengStephen J Russell Source Type: research

A Recombinant Bispecific CD20×CD95 Antibody With Superior Activity Against Normal and Malignant B-cells
A Recombinant Bispecific CD20×CD95 Antibody With Superior Activity Against Normal and Malignant B-cells Molecular Therapy 24, 298 (February 2016). doi:10.1038/mt.2015.209 Authors: Kristina Nalivaiko, Martin Hofmann, Karina Kober, Nadine Teichweyde, Peter H Krammer, Hans-Georg Rammensee, Ludger Grosse-Hovest & Gundram Jung (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Kristina NalivaikoMartin HofmannKarina KoberNadine TeichweydePeter H KrammerHans-Georg RammenseeLudger Grosse-HovestGundram Jung Source Type: research

Production of Recombinant Adeno-associated Virus Vectors Using Suspension HEK293 Cells and Continuous Harvest of Vector From the Culture Media for GMP FIX and FLT1 Clinical Vector
Samulski (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Joshua C GriegerStephen M SoltysRichard Jude Samulski Source Type: research

A Comprehensive Map of CNS Transduction by Eight Recombinant Adeno-associated Virus Serotypes Upon Cerebrospinal Fluid Administration in Pigs
ura Bacci, Enrico Maria Surace & Alessandro Fraldi (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Nicolina Cristina SorrentinoVeronica MaffiaSandra StrolloVincenzo CacaceNoemi RomagnoliAnna ManfrediDomenico VentrellaFrancesco DondiFrancesca BaroneMassimo GiuntiAnne-Renee GrahamYan HuangSusan L KalledAlberto AuricchioMaria Laura BacciEnrico Maria Surac Source Type: research

SET1A Cooperates With CUDR to Promote Liver Cancer Growth and Hepatocyte-like Stem Cell Malignant Transformation Epigenetically
& Dongdong Lu (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Tianming LiQidi ZhengJiahui AnMengying WuHaiyan LiXin GuiHu PuDongdong Lu Source Type: research

PAX4 Gene Transfer Induces α-to-β Cell Phenotypic Conversion and Confers Therapeutic Benefits for Diabetes Treatment
PAX4 Gene Transfer Induces α-to-β Cell Phenotypic Conversion and Confers Therapeutic Benefits for Diabetes Treatment Molecular Therapy 24, 251 (February 2016). doi:10.1038/mt.2015.181 Authors: Yanqing Zhang, Genevieve E Fava, Hongjun Wang, Franck Mauvais-Jarvis, Vivian A Fonseca & Hongju Wu (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Yanqing ZhangGenevieve E FavaHongjun WangFranck Mauvais-JarvisVivian A FonsecaHongju Wu Source Type: research

AAV6-mediated Cardiac-specific Overexpression of Ribonucleotide Reductase Enhances Myocardial Contractility
& Michael Regnier (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Stephen C KolwiczGuy L OdomSarah G NowakowskiFarid Moussavi-HaramiXiaolan ChenHans ReineckeStephen D HauschkaCharles E MurryGregory G MahairasMichael Regnier Source Type: research

Virus-mediated EpoR76E Therapy Slows Optic Nerve Axonopathy in Experimental Glaucoma
& Tonia S Rex (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Wesley S BondJessica Hines-BeardYPaul L GoldenMerryMara DavisAlma FarooqueRebecca M SappingtonDavid J CalkinsTonia S Rex Source Type: research

Suppression of EZH2 Prevents the Shift of Osteoporotic MSC Fate to Adipocyte and Enhances Bone Formation During Osteoporosis
hang & Yan Jin (Source: Molecular Therapy)
Source: Molecular Therapy - February 24, 2016 Category: Genetics & Stem Cells Authors: Huan JingLi LiaoYulin AnXiaoxia SuShiyu LiuYi ShuaiXinjing ZhangYan Jin Source Type: research