Pharmacokinetics and antinociceptive effects of the soluble epoxide hydrolase inhibitor t ‐TUCB in horses with experimentally induced radiocarpal synovitis
Journal of Veterinary Pharmacology and Therapeutics,Volume 41, Issue 2, Page 230-238, April 2018. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 25, 2017 Category: Veterinary Research Source Type: research

Pharmacokinetics of enrofloxacin and ciprofloxacin in Atlantic horseshoe crabs (Limulus polyphemus) after single injection
Journal of Veterinary Pharmacology and Therapeutics,Volume 41, Issue 2, Page 349-353, April 2018. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 25, 2017 Category: Veterinary Research Source Type: research

---
Journal of Veterinary Pharmacology and Therapeutics,Volume 41, Issue 2, Page 230-238, April 2018. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 25, 2017 Category: Veterinary Research Source Type: research

---
Journal of Veterinary Pharmacology and Therapeutics,Volume 41, Issue 2, Page 349-353, April 2018. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 25, 2017 Category: Veterinary Research Source Type: research

Pharmacokinetics of enrofloxacin and ciprofloxacin in Atlantic horseshoe crabs (Limulus polyphemus) after single injection
The pharmacokinetics of enrofloxacin and the metabolite ciprofloxacin were studied in horseshoe crabs after a single injection of 5 mg/kg. Twelve Atlantic horseshoe crabs (Limulus polyphemus) of undetermined age were injected with enrofloxacin into the dorsal cardiac sinus. Hemolymph samples were collected by syringe and needle at regular intervals for 120 hr. Samples were analyzed by high‐pressure liquid chromatography and compartmental analysis performed on the results. Following injection, the elimination half‐life (T½), peak concentration, area under the curve (AUC), and volume of distribution (VD) for enrofloxa...
Source: Journal of Veterinary Pharmacology and Therapeutics - October 25, 2017 Category: Veterinary Research Authors: A. Kirby, G. A. Lewbart, A. Hancock ‐Ronemus, M. G. Papich Tags: ORIGINAL ARTICLE Source Type: research

Postoperative pharmacokinetics of meloxicam in horses after surgery for colic syndrome
Journal of Veterinary Pharmacology and Therapeutics, EarlyView. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 22, 2017 Category: Veterinary Research Source Type: research

Ketoprofen pharmacokinetics of R ‐ and S‐isomers in juvenile loggerhead sea turtles (Caretta caretta) after single intravenous and single‐ and multidose intramuscular administration
Journal of Veterinary Pharmacology and Therapeutics,Volume 41, Issue 2, Page 340-348, April 2018. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 22, 2017 Category: Veterinary Research Source Type: research

Evaluation of the safety of daily administration of capromorelin in cats
Journal of Veterinary Pharmacology and Therapeutics,Volume 41, Issue 2, Page 324-333, April 2018. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 22, 2017 Category: Veterinary Research Source Type: research

Pharmacokinetics of furosemide administered 4 and 24  hours prior to high‐speed exercise in horses
Journal of Veterinary Pharmacology and Therapeutics,Volume 41, Issue 2, Page 224-229, April 2018. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 22, 2017 Category: Veterinary Research Source Type: research

---
Journal of Veterinary Pharmacology and Therapeutics, Ahead of Print. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 22, 2017 Category: Veterinary Research Source Type: research

---
Journal of Veterinary Pharmacology and Therapeutics,Volume 41, Issue 2, Page 340-348, April 2018. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 22, 2017 Category: Veterinary Research Source Type: research

---
Journal of Veterinary Pharmacology and Therapeutics,Volume 41, Issue 2, Page 324-333, April 2018. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 22, 2017 Category: Veterinary Research Source Type: research

---
Journal of Veterinary Pharmacology and Therapeutics,Volume 41, Issue 2, Page 224-229, April 2018. (Source: Journal of Veterinary Pharmacology and Therapeutics)
Source: Journal of Veterinary Pharmacology and Therapeutics - October 22, 2017 Category: Veterinary Research Source Type: research

Postoperative pharmacokinetics of meloxicam in horses after surgery for colic syndrome
NSAIDs are often used in horses with colic syndrome during the postoperative period, due to their ability to contrast endotoxemia and to promote an analgesic and anti‐inflammatory effect. As the pharmacokinetics of a drug are often modified in unhealthy animals compared to healthy subjects, the aim of this study was to evaluate the pharmacokinetic profile of meloxicam after i.v. administration in horses undergoing laparotomy for colic syndrome. Eight horses received 0.6 mg/kg of meloxicam i.v. towards the end of surgery. Blood samples were taken at scheduled time points during the following 24 hr. The serum concentrati...
Source: Journal of Veterinary Pharmacology and Therapeutics - October 22, 2017 Category: Veterinary Research Authors: A. Di Salvo, M. Giorgi, S. Nannarone, H. K. Lee, J. Corsalini, G. della Rocca Tags: PHARMACOKINETIC REPORT Source Type: research

Pharmacokinetics of furosemide administered 4 and 24  hours prior to high‐speed exercise in horses
Furosemide is a diuretic agent used commonly in racehorses to attenuate the bleeding associated with exercise‐induced pulmonary hemorrhage (EIPH). The current study describes serum and urine concentrations and the pharmacokinetics of furosemide following administration at 4 and 24 hrs prior to maximal exercise. Eight exercised adult Thoroughbred horses received a single IV administration of 250 mg of furosemide at 4 and 24 hrs prior to maximal exercise on a high‐speed treadmill. Blood and urine samples were collected at time 0 and at various times for up to 72 hrs and furosemide concentrations determined using liqu...
Source: Journal of Veterinary Pharmacology and Therapeutics - October 22, 2017 Category: Veterinary Research Authors: H. K. Knych, A. Vale, W. D. Wilson, P. H. Kass, R. M. Arthur, J. H. Jones Tags: ORIGINAL ARTICLE Source Type: research