JCN Calendar of Events
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - September 12, 2016 Category: Neurology Tags: & lt;I gt;JCN lt;/I gt; Calendar of Events Source Type: research

Comment on "Pattern-Reversal Visual Evoked Potential Parameters and Migraine in the Teenage Population"
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - September 12, 2016 Category: Neurology Authors: Gundogan, F. C., Ayyildiz, O., Ozge, G., Mutlu, F. M. Tags: Correspondence Source Type: research

Educational Intervention Improves Compliance With AAN Guidelines for Return Epilepsy Visits: A Quality Improvement Project
In 2011, the American Academy of Neurology (AAN) released guidelines for return seizure visits detailing 8 points that should be addressed during such visits. These guidelines are designed to improve routine follow-up care for epilepsy patients. The authors performed a quality improvement project aimed at increasing compliance with these guidelines after educating providers about them. The authors performed a chart review before and after an intervention which included: education regarding the guidelines, providing materials to remind providers of the guidelines, and templates to facilitate compliance. The authors reviewed...
Source: Journal of Child Neurology - September 12, 2016 Category: Neurology Authors: Nelson, G. R., Filloux, F. M., Kerr, L. M. Tags: Original Articles Source Type: research

A Qualitative Study of Physician Perspectives on Prognostication in Neonatal Hypoxic Ischemic Encephalopathy
This study aimed, through semistructured interviews with neonatologists and pediatric neurologists, to understand the practice of prognostication. Qualitative thematic content analysis was used for data analysis. The authors report 2 main findings: (1) neurological prognosis remains fundamental to quality-of-life predictions and considerations of best interest, and (2) magnetic resonance imaging is presented to parents with a greater degree of certainty than actually exists. Further research is needed to explore both the parental perspective and, prospectively, the impact of different clinical approaches and styles to prog...
Source: Journal of Child Neurology - September 12, 2016 Category: Neurology Authors: Rasmussen, L. A., Bell, E., Racine, E. Tags: Original Articles Source Type: research

The Relation of Focal Lesions to Cortical Thickness in Pediatric Traumatic Brain Injury
In a sample of children with traumatic brain injury, this magnetic resonance imaging (MRI)–based investigation examined whether presence of a focal lesion uniquely influenced cortical thickness in any brain region. Specifically, the study explored the relation of cortical thickness to injury severity as measured by Glasgow Coma Scale score and length of stay, along with presence of encephalomalacia, focal white matter lesions or presence of hemosiderin deposition as a marker of shear injury. For comparison, a group of children without head injury but with orthopedic injury of similar age and sex were also examined. B...
Source: Journal of Child Neurology - September 12, 2016 Category: Neurology Authors: Bigler, E. D., Zielinski, B. A., Goodrich-Hunsaker, N., Black, G. M., Huff, B. S. T., Christiansen, Z., Wood, D.-M., Abildskov, T. J., Dennis, M., Taylor, H. G., Rubin, K., Vannatta, K., Gerhardt, C. A., Stancin, T., Yeates, K. O. Tags: Original Articles Source Type: research

Differences in Metabolite Concentrations Between the Hemispheres of the Brain in Healthy Children: A Proton Magnetic Resonance Spectroscopy Study (1HMRS)
The aim of this 1HMRS study was to identify hemispheric asymmetries in metabolismus in healthy children. The study group consisted of children of both sexes aged 6 to 15. Concentrations of 6 metabolites occurring in the brain were determined for 6 locations: hippocampus, frontal lobe, and basal ganglia in the left and right hemispheres. There were no hemispheric differences in the metabolites’ concentrations in the brain in children when the variable of sex was disregarded. Only in the group of boys and in the group of girls did the findings show few discrepancies. In none of these groups, relative concentrations to ...
Source: Journal of Child Neurology - September 12, 2016 Category: Neurology Authors: Cichocka, M., Kozub, J., Karcz, P., Urbanik, A. Tags: Original Articles Source Type: research

Motor Difficulties and Their Effect on Participation in School-Aged Children
Conclusions: Motor difficulties persist into school years. Children with motor difficulties manifest performance skill problems, however they succeed in narrowing the gap and participate similar to their peers. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - September 12, 2016 Category: Neurology Authors: Mimouni-Bloch, A., Tsadok-Cohen, M., Bart, O. Tags: Original Articles Source Type: research

Medical Comorbidity of Attention-Deficit/Hyperactivity Disorder in US Adolescents
This article provides the first systematic evaluation on the medical comorbidity of ADHD in a nationally representative sample (National Comorbidity Replication Survey–Adolescent Supplement; N = 6483) using formal diagnostic criteria. Survey-weighted odds ratios adjusted for demographics, additional medical, and mental disorders were calculated for associations between ADHD and medical conditions. Models adjusted for demographics revealed significantly increased odds of allergy, asthma, enuresis, headache/migraine, and serious stomach or bowel problems. After adjusting for comorbidity, across the medical conditions, ...
Source: Journal of Child Neurology - September 12, 2016 Category: Neurology Authors: Jameson, N. D., Sheppard, B. K., Lateef, T. M., Vande Voort, J. L., He, J.-P., Merikangas, K. R. Tags: Original Articles Source Type: research

Evaluation of Preoperative Amplitude-Integrated Electroencephalography (aEEG) Monitoring for Predicting Long-Term Neurodevelopmental Outcome Among Infants Undergoing Major Surgery in the Neonatal Period
The authors aimed to evaluate preoperative amplitude-integrated electroencephalography (aEEG) patterns for predicting neurodevelopmental outcome among infants undergoing major surgery in the neonatal period. They retrospectively reviewed the preoperative aEEG data of 58 neonates who had undergone major neonatal surgery between 2006 and 2008. The authors classified aEEGs using a weighted background score. Neurodevelopmental outcome was assessed at 3 years of age using the Bayley Scales of Toddler and Infant Development III. Over a third of infants (36%) showed an abnormal aEEG background. Seizure activity was identified in ...
Source: Journal of Child Neurology - September 12, 2016 Category: Neurology Authors: Mehta, B., Hunt, R., Walker, K., Badawi, N. Tags: Original Articles Source Type: research

JCN Calendar of Events
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - August 8, 2016 Category: Neurology Tags: & lt;I gt;JCN lt;/I gt; Calendar of Events Source Type: research

Epidemiology of Pediatric Convulsive Status Epilepticus With Fever in the Emergency Department: A Cohort Study of 381 Consecutive Cases
Pediatric convulsive status epilepticus with fever is common in the emergency setting but leads to severe neurological sequelae in some patients. To explore the epidemiology of convulsive status epilepticus with fever, a retrospective cohort covering all convulsive status epilepticus cases with fever seen in the emergency department of a tertiary care children’s hospital were consecutively collected. Of the 381 consecutive cases gathered, 81.6% were due to prolonged febrile seizure, 6.6% to encephalopathy/encephalitis, 0.8% to meningitis, and 7.6% to epilepsy. In addition, seizures were significantly longer in enceph...
Source: Journal of Child Neurology - August 8, 2016 Category: Neurology Authors: Hayakawa, I., Miyama, S., Inoue, N., Sakakibara, H., Hataya, H., Terakawa, T. Tags: Original Articles Source Type: research

The Dopamine Receptor D5 May Influence Age of Onset: An Exploratory Study on Indo-Caucasoid ADHD Subjects
The objective was to investigate contribution of the dopamine receptor 5 (DRD5) gene variants in the symptoms of attention-deficit/hyperactivity disorder (ADHD) probands since brain regions identified to be affected in these group of patients have higher expression of the DRD5 receptor. Out of 22 exonic variants, 19 were monomorphic in the Indo-Caucasoid individuals. rs6283 "C" and rs113828117 "A" exhibited significant higher occurrence in families with ADHD probands. Several haplotypes showed biased occurrence in the probands. Early and late onset groups exhibited significantly different genotypic frequencies. A new G>...
Source: Journal of Child Neurology - August 8, 2016 Category: Neurology Authors: Maitra, S., Sarkar, K., Sinha, S., Mukhopadhyay, K. Tags: Original Articles Source Type: research

Color Vision Deficiency and Functional Disorders Among Israeli Male Adolescents Between 2007 and 2013
We examined the association of color vision deficiency with functional conditions, including ADHD, irritable bowel syndrome, enuresis and somatoform disorders, in a large population of male adolescents. We included all Israeli male adolescents that underwent medical and cognitive examinations during conscription between the years 2007 and 2013. The prevalence of ADHD, irritable bowel syndrome, enuresis, and somatoform disorders among color vision deficiency patients was compared to a control group. The study included 305 964 males aging 17 ± 0.6, of which 7584 (2.5%) had color vision deficiency. Using a multivariabl...
Source: Journal of Child Neurology - August 8, 2016 Category: Neurology Authors: Berger, A., Findler, M., Maymon, D., Korach, T., Yativ, O. F., Gronovich, Y., Hassidim, A. Tags: Original Articles Source Type: research

Association Between Perinatal Hypoxic-Ischemic Conditions and Attention-Deficit/Hyperactivity Disorder: A Meta-Analysis
Conclusion: Our results support that perinatal hypoxia-ischemia may contribute to ADHD. However, more clinical studies are warranted. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - August 8, 2016 Category: Neurology Authors: Zhu, T., Gan, J., Huang, J., Li, Y., Qu, Y., Mu, D. Tags: Original Articles Source Type: research

Clinical Trial of Erythropoietin in Young Children With Cerebral Palsy
This study was conducted to assess the safety and efficacy of recombinant human erythropoietin in young children with cerebral palsy aged between 6 months and 3 years. All participants received subcutaneous recombinant human erythropoietin and 8 weeks of rehabilitation therapy. Adverse events, changes of vital signs, and hematologic tests were monitored up to 8 weeks postinjection. Functional measures of development at 4 and 8 weeks postinjection were compared with baseline values, and improvements were compared with those of an age-matched historical control group. Nine participants completed the trial from June 2012 to F...
Source: Journal of Child Neurology - August 8, 2016 Category: Neurology Authors: Cho, K. H., Min, K., Lee, S. H., Lee, S., An, S. A., Kim, M. Tags: Original Articles Source Type: research