Is Male Migraine Associated With Color Vision Deficiency? Findings Among Israeli Adolescents Between 2007 and 2013
Conclusions: The authors found an association between color vision deficiency and migraine in male adolescents. The study results lay the basis for further research into male migraine, as well as the visual aspects of migraine. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - March 16, 2016 Category: Neurology Authors: Berger, A., Findler, M., Korach, T., Yativ, O. F., Gronovich, Y., Hassidim, A. Tags: Original Articles Source Type: research

Structural and Perfusion Abnormalities of Brain on MRI and Technetium-99m-ECD SPECT in Children With Cerebral Palsy: A Comparative Study
This study was undertaken to demonstrate structural and perfusion brain abnormalities. Fifty-six children diagnosed clinically as having cerebral palsy were studied between 1 to 14 years of age and were subjected to 3 Tesla magnetic resonance imaging (MRI). Brain and Technetium-99m-ECD brain single-photon emission computed tomography (SPECT) scan. Male to female ratio was 1.8:1 with a mean age of 4.16 ± 2.274 years. Spastic cerebral palsy was the most common type, observed in 91%. Birth asphyxia was the most common etiology (69.6%). White matter changes (73.2%) such as periventricular leukomalacia and corpus callosa...
Source: Journal of Child Neurology - March 16, 2016 Category: Neurology Authors: Rana, K. S., Narwal, V., Chauhan, L., Singh, G., Sharma, M., Chauhan, S. Tags: Original Articles Source Type: research

Clinical Impact of Epileptiform Discharge in Children With Attention-Deficit/Hyperactivity Disorder (ADHD)
The aim of this study was to investigate the prevalence and clinical significance of epileptiform discharges in patients with attention-deficit/hyperactivity disorder (ADHD). The authors retrospectively reviewed 180 children who were diagnosed with ADHD and had an electroencephalography (EEG) recording. Epileptiform discharges were found in 29 (16.1%) of 180 patients with ADHD. Of these, 15 (8.3%) had generalized epileptiform discharges and 14 (7.7%) had focal epileptiform discharges. The focal epileptiform discharges were most prevalent from the frontal (5/14) and rolandic area (5/14). Among the 29 patients with epileptif...
Source: Journal of Child Neurology - March 16, 2016 Category: Neurology Authors: Lee, E. H., Choi, Y. S., Yoon, H. S., Bahn, G. H. Tags: Original Articles Source Type: research

Survey of Neurological Disorders in Children Aged 9-15 Years in Northern India
The prevalence of neurological disorders in resource-poor settings, although likely to be high, is largely unexplored. The prevalence and risk factors for neurological disorders, including epilepsy and intellectual, motor, vision, and hearing deficits, in children aged 9 to 15 years in the community were investigated. A new instrument was developed, validated, and used in a 2-stage community survey for neurological disorders in Lucknow, India. Screen-positives and random proportion of screen-negatives were validated using predefined criteria. Prevalence of different neurological disorders was calculated by weighted proport...
Source: Journal of Child Neurology - March 16, 2016 Category: Neurology Authors: Kumar, R., Bhave, A., Bhargava, R., Agarwal, G. G. Tags: Original Articles Source Type: research

Visual Attention in Children With Migraine: The Importance of Prophylaxis
This study aimed to compare the visual attention performance of children newly diagnosed with migraine, children undergoing migraine prophylaxis, and a healthy control group. Eighty-two children aged 8 to 12 years were divided into 3 groups: untreated migraine (n = 30), migraine prophylaxis (n = 22), and control (n = 30). All were subjected to a visual attention assessment with the Trail Making Test parts A and B, Letter-Cancellation Test, and the Brazilian Visual Attention Test 3rd edition. Although performance in attention tasks was within the normal range in all groups, children with untreated migraine performed signifi...
Source: Journal of Child Neurology - March 16, 2016 Category: Neurology Authors: Villa, T. R., Agessi, L. M., Moutran, A. R. C., Gabbai, A. A., Carvalho, D. d. S. Tags: Original Articles Source Type: research

Different Neurologic Aspects of Nutritional B12 Deficiency in Infancy
The objective of this study is to evaluate neurologic problems caused by nutritional vitamin B12 deficiency in infancy. Twenty-four cases between 2 and 18 months of age with neurologic symptoms and/or signs and diagnosed as nutritional vitamin B12 deficiency were analyzed. The most common symptoms were developmental retardation, afebrile seizures, and involuntary movements. The mean vitamin B12 levels were lower in patients with both neurologic and extraneurologic involvement when compared to those with only neurologic symptoms. All of the cases were treated with vitamin B12. In patients with severe deficiencies, involunta...
Source: Journal of Child Neurology - March 16, 2016 Category: Neurology Authors: Yilmaz, S., Serdaroglu, G., Tekgul, H., Gokben, S. Tags: Original Articles Source Type: research

Lack of Association Between Polymorphisms in Dopa Decarboxylase and Dopamine Receptor-1 Genes With Childhood Autism in Chinese Han Population
This study is to determine the association of single-nucleotide polymorphisms in dopa decarboxylase (DDC) and dopamine receptor-1 (DRD1) genes with childhood autism, in a Chinese Han population. A total of 211 autistic children and 250 age- and gender-matched healthy controls were recruited. The severity of disease was determined by Children Autism Rating Scale scores. TaqMan Probe by real-time polymerase chain reaction was used to determine genotypes and allele frequencies of single-nucleotide polymorphism rs6592961 in DDC and rs251937 in DRD1. Case-control and case-only studies were respectively performed, to determine t...
Source: Journal of Child Neurology - March 16, 2016 Category: Neurology Authors: Yu, H., Liu, J., Yang, A., Yang, G., Yang, W., Lei, H., Quan, J., Zhang, Z. Tags: Original Articles Source Type: research

Reliability of Early Magnetic Resonance Imaging (MRI) and Necessity of Repeating MRI in Noncooled and Cooled Infants With Neonatal Encephalopathy
In cooled newborns with encephalopathy, although late magnetic resonance imaging (MRI) scan (10-14 days of age) is reliable in predicting long-term outcome, it is unknown whether early scan (3-6 days of life) is. We compared the predominant pattern and extent of lesion between early and late MRI in 89 term neonates with neonatal encephalopathy. Forty-three neonates (48%) were cooled. The predominant pattern of lesions and the extent of lesion in the watershed region agreed near perfectly in noncooled (kappa = 0.94; k = 0.88) and cooled (k = 0.89; k = 0.87) infants respectively. There was perfect agreement in the extent of ...
Source: Journal of Child Neurology - March 16, 2016 Category: Neurology Authors: Chakkarapani, E., Poskitt, K. J., Miller, S. P., Zwicker, J. G., Xu, Q., Wong, D. S. T., Roland, E. H., Hill, A., Chau, V. Tags: Original Articles Source Type: research

Epilepsy Following Neonatal Seizures Secondary to Hemorrhagic Stroke in Term Neonates
Intracranial hemorrhage accounts for about 50% of all pediatric stroke. Studies of term infants with intracranial hemorrhage have shown favorable motor and cognitive outcome. The goal of this study was to examine the risk of developing epilepsy in full-term infants with intracranial hemorrhage. A retrospective study was performed of term neonates (greater than or equal to 37 weeks gestation) with intracranial hemorrhage and confirmed seizures. Fifteen patients with intracranial hemorrhage and neonatal seizures were identified. Four patients did not have follow-up information beyond the neonatal period (1 death, 3 lost to f...
Source: Journal of Child Neurology - March 16, 2016 Category: Neurology Authors: Venkatesan, C., Millichap, J. J., Krueger, J. M., Nangia, S., Ritacco, D. G., Stack, C., Nordli, D. R. Tags: Original Articles Source Type: research

JCN Calendar of Events
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - February 9, 2016 Category: Neurology Tags: & lt;I gt;JCN lt;/I gt; Calendar of Events Source Type: research

Facial Expressions in Small for Gestational Age Newborns
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - February 9, 2016 Category: Neurology Authors: Laureano, D. P., Molle, R. D., Portella, A. K., Silveira, P. P. Tags: Correspondence Source Type: research

Book Review: Color Atlas of Neurology
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - February 9, 2016 Category: Neurology Authors: Keator, C. G. Tags: Book Review Source Type: research

DNA Repair Dysfunction and Neurodegeneration: Lessons From Rare Pediatric Disorders
This article outlines neurodegenerative symptoms seen in nucleotide excision repair disorders and explores the role that nucleotide excision repair dysfunction can play in the pathogenesis of chronic neurodegenerative diseases. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - February 9, 2016 Category: Neurology Authors: Shabbir, S. H. Tags: Topical Review Articles Source Type: research

Medical Marijuana in Pediatric Neurological Disorders
Marijuana and marijuana-based products have been used to treat medical disease. Recently, derivatives of the plant have been separated or synthesized to treat various neurological disorders, many of them affecting children. Unfortunately, data are sparse in regard to treating children with neurologic illness. Therefore, formal conclusions about the potential efficacy, benefit, and adverse effects for these products cannot be made at this time. Further robust research using strong scientific methodology is desperately needed to formally evaluate the role of these products in children. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - February 9, 2016 Category: Neurology Authors: Patel, A. D. Tags: Topical Review Articles Source Type: research

Pediatric Gliomatosis Cerebri: A Review of 15 Years
We present 10 children who either presented to the Weill Cornell Medical College or enrolled in the institution’s Gliomatosis Cerebri International Registry alongside a cohort of 89 pediatric patients reported in the literature between 2000 and 2014. Age ranged from 4 months to 21 years, with a male to female ratio of 1.71. Median overall survival for patients in the registry cohort was 17 months (n = 10) and for the historic cohort was 13 months (n = 52). Overall survival was analyzed for the combined cohort and was significantly longer when presenting at age ≥10 (20 vs 10 months), for boys (18 vs 11 months), and...
Source: Journal of Child Neurology - February 9, 2016 Category: Neurology Authors: George, E., Settler, A., Connors, S., Greenfield, J. P. Tags: Topical Review Articles Source Type: research