The Clinical Characteristics and Treatment Response in Children with West Syndrome in a Developing Country: A Retrospective Case Record Analysis
This study describes the clinical characteristics, treatment, and outcome of children with West syndrome in a tertiary care hospital in north India. Overall, 310 case records diagnosed from January 2009 to June 2012 were reviewed. The median age of onset of spasms was 5 months (interquartile range = 2.5-7 months). The predominant underlying etiology was perinatal cerebral ischemia (55%). Adrenocorticotropic hormone or oral steroids were received by 92% children, of whom 43% became seizure free. Median lag time for appropriate treatment initiation was significantly less in patients who became seizure free as compared to tho...
Source: Journal of Child Neurology - September 18, 2015 Category: Neurology Authors: Gulati, S., Jain, P., Kannan, L., Sehgal, R., Chakrabarty, B. Tags: Original Articles Source Type: research
Association of Rotavirus With Seizures Accompanied by Cerebral White Matter Injury in Neonates
This study indicated an association between rotavirus and seizures accompanied by diffuse cerebral white matter lesions in neonates. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - September 18, 2015 Category: Neurology Authors: Oh, K. W., Moon, C. H., Lee, K. Y. Tags: Original Articles Source Type: research
Vitamin D Deficiency in Children With Newly Diagnosed Idiopathic Epilepsy
This study includes 60 newly diagnosed idiopathic epilepsy patients and 101 healthy controls (between the ages of 5 and 16). Each group was also divided into two subgroups according to seasonal changes in terms of months of longer versus shorter daylight. We retrospectively evaluated the levels of calcium, phosphorus, alkaline phosphatase, parathyroid hormone, and 25-OH vitamin-D3 in the study participants. Levels below 20 ng/ml were defined as vitamin D deficiency and levels of 20-30 ng/ml as insufficiency. There were no significant differences in age, gender distribution and levels of calcium, phosphorus, alkaline phosph...
Source: Journal of Child Neurology - September 18, 2015 Category: Neurology Authors: Sonmez, F. M., Donmez, A., Namuslu, M., Canbal, M., Orun, E. Tags: Original Articles Source Type: research
Emergency Department Management of Pediatric Unprovoked Seizures and Status Epilepticus in the State of Illinois
The purpose of this survey and record review was to characterize emergency department management of unprovoked seizures and status epilepticus in children in Illinois. The survey was sent to 119 participating emergency departments in the Emergency Medical Services for Children program; responses were received from 103 (88% response rate). Only 44% of the emergency departments had a documented protocol for seizure management. Only 12% of emergency departments had child neurology consultation available at all times. Record review showed that 58% of patients were discharged home, 26% were transferred to another institution, a...
Source: Journal of Child Neurology - September 18, 2015 Category: Neurology Authors: Taylor, C., Piantino, J., Hageman, J., Lyons, E., Janies, K., Leonard, D., Kelley, K., Fuchs, S. Tags: Original Articles Source Type: research
Prevalence of Epileptiform Discharges in Healthy Infants
Most studies on epileptiform discharges in young children were performed using analog electroencephalographic (EEG) recording systems and a limited numbers of electrodes that might have a lower detection rate for epileptiform discharges than modern digital recording systems. Knowing the prevalence of epileptiform discharges in healthy children is critical for a valid interpretation of findings in patients with a suspected epileptic disorder. We reviewed EEG recordings of 393 otherwise healthy children aged 12 to 60 months using digital EEG recording with respect to epileptiform discharges. We found epileptiform discharges ...
Source: Journal of Child Neurology - September 18, 2015 Category: Neurology Authors: Bihege, C. J., Langer, T., Jenke, A. C. W., Bast, T., Borusiak, P. Tags: Original Articles Source Type: research
