Electroretinography and Visual Evoked Potentials in Childhood Brain Tumor Survivors
This population-based cross-sectional study evaluates the clinical value of electroretinography and visual evoked potentials in childhood brain tumor survivors. A flash electroretinography and a checkerboard reversal pattern visual evoked potential (or alternatively a flash visual evoked potential) were done for 51 survivors (age 3.8-28.7 years) after a mean follow-up time of 7.6 (1.5-15.1) years. Abnormal electroretinography was obtained in 1 case, bilaterally delayed abnormal visual evoked potentials in 22/51 (43%) cases. Nine of 25 patients with infratentorial tumor location, and altogether 12 out of 31 (39%) patients w...
Source: Journal of Child Neurology - June 13, 2016 Category: Neurology Authors: Pietilä, S., Lenko, H. L., Oja, S., Koivisto, A.-M., Pietilä, T., Mäkipernaa, A. Tags: Original Articles Source Type: research
Acute Cerebellitis in Children: A Many-Faceted Disease
We present the clinical, laboratory, and radiologic data in 9 children diagnosed with acute cerebellitis, who were identified by database search in our pediatric medical center from January 2000 to November 2014. The main presenting symptom was headache, and the main presenting sign was ataxia. Bilateral diffuse hemispheric involvement was the most common imaging finding at presentation. Mycoplasma pneumoniae was the most common infectious pathogen found. Treatment included steroids in all cases, antibiotics in 4, and intravenous immunoglobulins in 6. Six patients had a full recovery, and 3 had residual neurologic complica...
Source: Journal of Child Neurology - June 13, 2016 Category: Neurology Authors: Kornreich, L., Shkalim-Zemer, V., Levinsky, Y., Abdallah, W., Ganelin-Cohen, E., Straussberg, R. Tags: Original Articles Source Type: research
The Impact of a 35-Week Long-Term Exercise Therapy on Psychosocial Health of Children With Benign Epilepsy
The purpose of this study was to evaluate the feasibility of a 35-week exercise program and its efficacy on neurocognitive and psychological variables in children with benign epilepsy with centrotemporal spikes. Ten children with benign epilepsy with centrotemporal spikes (aged 8 to 12 years) completed a 35-week exercise program consisting of supervised sport activities for 5 weeks and home-based exercise program for 30 weeks. The children and their parents participated in neurocognitive and psychological evaluations including measures of attention, executive function, behaviors, and quality of life at baseline and postexe...
Source: Journal of Child Neurology - June 13, 2016 Category: Neurology Authors: Eom, S., Lee, M. K., Park, J.-H., Lee, D., Kang, H.-C., Lee, J. S., Jeon, J. Y., Kim, H. D. Tags: Original Articles Source Type: research
Quantitative Analysis of Lower Leg Adipose Tissue Distribution in Youth with Myelomeningocele
This study quantified lower leg bone, muscle, and adipose tissue volume in children with myelomeningocele, classifying adipose as subcutaneous or muscle-associated. Eighty-eight children with myelomeningocele and 113 children without myelomeningocele underwent lower leg computed tomographic scans. Subcutaneous and muscle-associated adipose were classified based on location relative to the crural fascia. No differences were seen in subcutaneous adipose. Higher level disease severity was associated with increased muscle-associated adipose volume and decreased muscle volume. Bone volume tended to decrease with higher levels o...
Source: Journal of Child Neurology - June 13, 2016 Category: Neurology Authors: Lorenzana, D. J., Mueske, N. M., Ryan, D. D., Van Speybroeck, A. L., Wren, T. A. L. Tags: Original Articles Source Type: research
Head Impact Exposure During a Weekend Youth Soccer Tournament
This study adds to the limited data regarding head impacts in youth soccer. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - June 13, 2016 Category: Neurology Authors: Chrisman, S. P. D., Mac Donald, C. L., Friedman, S., Andre, J., Rowhani-Rahbar, A., Drescher, S., Stein, E., Holm, M., Evans, N., Poliakov, A. V., Ching, R. P., Schwien, C. C., Vavilala, M. S., Rivara, F. P. Tags: Original Articles Source Type: research
Sensory Processing Difficulties in Opsoclonus-Myoclonus Syndrome: A Pilot Project of Presentation and Possible Prevalence
Opsoclonus-myoclonus syndrome is a rare but serious neurological condition resulting in loss of control of eye movements, often accompanied by difficulties in posture and movement control with reports of sensory sensitivities potentially impacting on behavior. This pilot study characterizes the presence of atypical sensory behaviors in opsoclonus-myoclonus syndrome through questionnaire survey of a cohort of families. The Short Sensory Profile, Vineland Adaptive Behavior Scale, and Developmental Behaviour Checklist were distributed to 30 families; 16 were returned anonymously. Atypical sensory behaviors were identified in ...
Source: Journal of Child Neurology - June 13, 2016 Category: Neurology Authors: Green, D., Lim, M., Lang, B., Pohl, K., Turk, J. Tags: Original Articles Source Type: research
Guanfacine Use in Children With Down Syndrome and Comorbid Attention-Deficit Hyperactivity Disorder (ADHD) With Disruptive Behaviors
The purpose of this study was to characterize children with Down syndrome and attention-deficit hyperactivity disorder (ADHD) with disruptive behaviors using the Aberrant Behavior Checklist (ABC), and to measure the treatment effects of guanfacine on maladaptive behaviors. Subjects were enrolled from a group of outpatients who visited our clinic between 2002 and 2007. Subjects (N = 23) were children with Down syndrome ages 4 to 12 years (mean 7.4 ± 4.1), who met criteria for ADHD according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. The Aberrant Behavior Checklist Irritability and H...
Source: Journal of Child Neurology - June 13, 2016 Category: Neurology Authors: Capone, G. T., Brecher, L., Bay, M. Tags: Original Articles Source Type: research
JCN Calendar of Events
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - May 10, 2016 Category: Neurology Tags: & lt;I gt;JCN lt;/I gt; Calendar of Events Source Type: research
Correspondence on "Neurocutaneous Syndromes and Brain Tumors"
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - May 10, 2016 Category: Neurology Authors: Toledano, H., Barnes-Kedar, I., Baris, H. N. Tags: Correspondence Source Type: research
An Autoimmune Basis for Diabetes-Related Chorea?
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - May 10, 2016 Category: Neurology Authors: Zekeridou, A., Lennon, V. A. Tags: Correspondence Source Type: research
Book Review: Practical Epilepsy
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - May 10, 2016 Category: Neurology Authors: Perry, M. S. Tags: Book Review Source Type: research
Early-Onset Mild Type Leukoencephalopathy Caused by a Homozygous EARS2 Mutation
Childhood leukoencephalopathies are a broad class of diseases, which are extremely rare. The treatment and classification of these disorders are both challenging. Nearly half of children presenting with a leukoencephalopathy remain without a specific diagnosis. Leukoencephalopathy with thalamus and brain stem involvement and high lactate (LTBL) is a newly described childhood leukoencephalopathy caused by mutations in the gene encoding a mitochondrial aminoacyl-tRNA synthetase specific for glutamate, EARS2. Magnetic resonance images show a characteristic leukoencephalopathy with thalamic and brain stem involvement. Here, we...
Source: Journal of Child Neurology - May 10, 2016 Category: Neurology Authors: Taskin, B. D., Karalok, Z. S., Gurkas, E., Aydin, K., Aydogmus, U., Ceylaner, S., Karaer, K., Yilmaz, C., Pearl, P. L. Tags: Other Source Type: research
Early-Onset Multiple Sclerosis in Isfahan, Iran: Report of the Demographic and Clinical Features of 221 Patients
This study indicated that early-onset multiple sclerosis is not rare condition and overwhelmingly affects girls even at prepubertal onset. Physicians should consider multiple sclerosis in suspicious pediatric cases. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - May 10, 2016 Category: Neurology Authors: Etemadifar, M., Nourian, S.-M., Nourian, N., Abtahi, S.-H., Sayahi, F., Saraf, Z., Fereidan-Esfahani, M. Tags: Original Articles Source Type: research
Is Celiac Disease an Etiological Factor in Children With Migraine?
To determine the prevalence of celiac disease in children and adolescents with migraine, the authors investigated serum levels of tissue transglutaminase antibody immunoglobulin A and total immunoglobulin A from 81 children with migraine and in a healthy control group of 176 children. Study participants who were positive for tissue transglutaminase immunoglobulin A antibodies underwent a duodenal biopsy. Two patients in the migraine group (2.5%) and 1 in the control group (0.57%) tested positive for serum tissue transglutaminase immunoglobulin A antibodies (P > .05). Duodenal biopsy did not confirm celiac disease in bot...
Source: Journal of Child Neurology - May 10, 2016 Category: Neurology Authors: Balcı, O., Yılmaz, D., Sezer, T., Hızlı, S. Tags: Original Articles Source Type: research
Efficacy and Tolerability of Lacosamide in the Treatment of Children With Refractory Generalized Epilepsy
Lacosamide is FDA-approved in patients 17 years or older with partial-onset epilepsy. We evaluated the efficacy and tolerability of lacosamide in children with refractory generalized epilepsy. We retrospectively reviewed records of 21 children with refractory generalized epilepsy treated with lacosamide in our institution from 2009–2013 divided into 2 subgroups- I, Lennox-Gastaut Syndrome, and II, other generalized epilepsies. Efficacy was defined as seizure freedom or ≥50% seizure reduction. Descriptive data analysis including seizure freedom was compared using c2 analysis. There were eleven females and ten males...
Source: Journal of Child Neurology - May 10, 2016 Category: Neurology Authors: Miskin, C., Khurana, D. S., Valencia, I., Legido, A., Hasbani, D. M., Carvalho, K. S. Tags: Original Articles Source Type: research
