Evaluation of Executive Functions in Patients With Childhood Absence Epilepsy
Conclusion: Long-term risk for learning impairments, failure in executive abilities, and short-term memory and attention disorders can occur in children with absence epilepsy. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - May 10, 2016 Category: Neurology Authors: Gencpinar, P., Kalay, Z., Turgut, S., Bozkurt, O., Duman, O., Ozel, D., Haspolat, S. Tags: Original Articles Source Type: research

Recording of Neonatal Seizures in Birth Certificates, Maternal Interviews, and Hospital Discharge Abstracts in a Cerebral Palsy Case-Control Study in Michigan
We evaluated the recording of neonatal seizures in birth certificates, hospital discharge abstracts, and maternal interviews in 372 children, 198 of them with cerebral palsy, born in Michigan hospitals from 1993 to 2010. In birth certificates, we examined checkbox items "seizures" or "seizure or serious neurologic dysfunction"; in hospital discharge abstracts ICD-9-CM codes 779.0, 345.X, and 780.3; and in maternal interviews a history of seizures or convulsions on day 1 of life recalled 2-16 years later. In 27 neonates, 38 neonatal seizures were recorded in 1 or more sources, 17 in discharge abstracts, 20 in maternal inter...
Source: Journal of Child Neurology - May 10, 2016 Category: Neurology Authors: Li, Q., Lenski, M., Copeland, G., Kinsman, S. L., Francis, M., Kirby, R. S., Paneth, N. Tags: Original Articles Source Type: research

JCN Calendar of Events
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Tags: & lt;I gt;JCN lt;/I gt; Calendar of Events Source Type: research

Asymmetric Dimethylarginine as a Vascular Risk Factor in Antiepileptic Drug Treated Individuals
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Tasdemir, S., Oz, O. Tags: Correspondence Source Type: research

Letter to the Editor
(Source: Journal of Child Neurology)
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Towle, V. L., Lee, R., Spire, J.-P., Levelt, W. J. M. Tags: Other Source Type: research

Mapping the Knowledge Structure of Neonatal Hypoxic-Ischemic Encephalopathy Over the Past Decade: A Co-word Analysis Based on Keywords
The aim of this study was to analyze the knowledge structure and report the evolution of hypoxic-ischemic encephalopathy research over the past decade based on co-word analysis. Scientific publications focusing on neonatal hypoxic-ischemic encephalopathy were searched from the Web of Science database (January 2005 to December 2014). The keywords from these articles were extracted, and a knowledge network based on these keywords was built using Ucinet6.212 and NetDraw2.084 software. A total of 1892 papers were included, and 39 high-frequency keywords were defined. "HIE" and "neonate" located at the center of the knowledge n...
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Huang, J., Tang, J., Qu, Y., Zhang, L., Zhou, Y., Bao, S., Mu, D. Tags: Topical Review Articles Source Type: research

Noninvasive Brain Stimulation in Pediatric Attention-Deficit Hyperactivity Disorder (ADHD): A Review
Attention-deficit hyperactivity disorder (ADHD) is one of the most prevalent neurodevelopmental disorders in the pediatric population. The clinical management of ADHD is currently limited by a lack of reliable diagnostic biomarkers and inadequate therapy for a minority of patients who do not respond to standard pharmacotherapy. There is optimism that noninvasive brain stimulation may help to address these limitations. Transcranial magnetic stimulation and transcranial direct current stimulation are 2 methods of noninvasive brain stimulation that modulate cortical excitability and brain network activity. Transcranial magnet...
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Rubio, B., Boes, A. D., Laganiere, S., Rotenberg, A., Jeurissen, D., Pascual-Leone, A. Tags: Topical Review Articles Source Type: research

Evolution of Management of Intracranial Aneurysms in Children: A Systematic Review of the Modern Literature
Pediatric intracranial aneurysms are rare. Management of their more common adult counterparts was profoundly influenced by recent high-quality clinical studies. The aim of this review was to aggregate the modern pediatric data published in the wake of these studies and to analyze their impact on management of aneurysms in children. A systematic PubMed search identified 135 publications published between 2000 and 2015, accounting for 573 children and 656 aneurysms. Descriptive statistical analyses revealed differences between children and adults concerning demographics and aneurysm characteristics. A significant proportion ...
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Beez, T., Steiger, H.-J., Hänggi, D. Tags: Topical Review Articles Source Type: research

A Review of X-linked Charcot-Marie-Tooth Disease
X-linked Charcot-Marie-Tooth disease (CMTX) is the second common genetic variant of CMT. CMTX type 1 causes 90% of CMTX. The most important clinical features of CMTX are similar with other types of CMT; however, a few patients get the central nervous system involved with or without white matter lesions; males are more severely and earlier affected than females. In this review, the authors focus on the origin and classification of CMTX, the central nervous system manifestations of CMTX1, the possible mechanism by which GJB1 mutations cause CMT1X, and the emerging therapeutic strategies for CMTX. Moreover, several cases are ...
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Wang, Y., Yin, F. Tags: Topical Review Articles Source Type: research

Effects of Smart-Tablet-Based Neurofeedback Training on Cognitive Function in Children with Attention Problems
This study suggests that the smart-tablet-based neurofeedback training program might improve cognitive function in children with attention problems. (Source: Journal of Child Neurology)
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Shin, M.-S., Jeon, H., Kim, M., Hwang, T., Oh, S. J., Hwangbo, M., Kim, K. j. Tags: Original Articles Source Type: research

Estimating Epilepsy Incidence and Prevalence in the US Pediatric Population Using Nationwide Health Insurance Claims Data
This study aims to determine prevalence and incidence of epilepsy in the US pediatric population. We analyzed commercial claims and Medicaid insurance claims data between 2008 and 2012. Over 8 million continuously enrolled lives aged 0 to 19 years were included. Our definition of a prevalent case of epilepsy was based on International Classification of Diseases–coded diagnoses of epilepsy or seizures and evidence of prescribed antiepileptic drugs. Incident cases were identified in subjects continuously enrolled for ≥2 years of which the first 2 years had no indication of epilepsy or seizures. The overall prevalenc...
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Kim, H., Thurman, D. J., Durgin, T., Faught, E., Helmers, S. Tags: Original Articles Source Type: research

Childhood Basal Ganglia Stroke and its Association with Trivial Head Trauma
This study explored the clinical profile, risk factors, neuroimaging and outcome of childhood basal ganglia stroke. Children (6 months-12 years) with basal ganglia stroke registered between 2007-2011 were retrospectively enrolled, while newly diagnosed cases over the 2-year study period were enrolled prospectively. Children with recent trivial head trauma were compared with those without it. Of the 35 children enrolled, trivial head trauma was seen in 74%. The non–trivial head trauma group (n = 9) comprised unidentified etiology (4), Moyamoya syndrome (2), varicella infection (1), homocysteinemia (1), and probable mi...
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Jauhari, P., Sankhyan, N., Khandelwal, N., Singhi, P. Tags: Original Articles Source Type: research

A Family-Based Association Study of CYP11A1 and CYP11B1 Gene Polymorphisms With Autism in Chinese Trios
Autism spectrum disorder is a group of neurodevelopmental disorders with the higher prevalence in males. Our previous studies have indicated lower progesterone levels in the children with autism spectrum disorder, suggesting involvement of the cytochrome P-450scc gene (CYP11A1) and cytochrome P-45011beta gene (CYP11B1) as candidate genes in autism spectrum disorder. The aim of this study was to investigate the family-based genetic association between single-nucleotide polymorphisms, rs2279357 in the CYP11A1 gene and rs4534 and rs4541 in the CYP11B1 gene and autism spectrum disorder in Chinese children, which were selected ...
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Deng, H.-Z., You, C., Xing, Y., Chen, K.-Y., Zou, X.-B. Tags: Original Articles Source Type: research

Synaptogenesis and Myelination in the Nucleus/Tractus Solitarius: Potential Role in Apnea of Prematurity, Congenital Central Hypoventilation, and Sudden Infant Death Syndrome
Fetuses as early as 15 weeks’ gestation exhibit rhythmical respiratory movements shown by real-time ultrasonography. The nucleus/tractus solitarius is the principal brainstem respiratory center; other medullary nuclei also participate. The purpose was to determine temporal maturation of synaptogenesis. Delayed synaptic maturation may explain neurogenic apnea or hypoventilation of prematurity and some cases of sudden infant death syndrome. Sections of medulla oblongata were studied from 30 human fetal and neonatal brains 9 to 41 weeks’ gestation. Synaptophysin demonstrated the immunocytochemical sequence of syna...
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Sarnat, H. B., Flores-Sarnat, L. Tags: Original Articles Source Type: research

Pattern-Reversal Visual Evoked Potential Parameters and Migraine in the Teenage Population
Although migraine represents one of the most common form of primary headache in the teenage population, most neurophysiologic studies are only on the adulthood. We investigated 38 teenage patients with migraine with aura, 17 male and 21 female, with a mean age of 16.2 years, comparing them with gender- and age-matched patients with migraine without aura and healthy subjects. Also, characteristics of aura were correlated with pattern-reversal visual evoked potential parameters. There was a significant difference in left and right eye N2 wave latencies between migraine with aura and migraine without aura patients or healthy ...
Source: Journal of Child Neurology - April 12, 2016 Category: Neurology Authors: Jancic, J., Petrusic, I., Pavlovski, V., Savkovic, Z., Vucinic, D., Martinovic, Z. Tags: Original Articles Source Type: research