Fundamental and Clinical Pharmacology 
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Treating hepatic encephalopathy in cirrhotic patients admitted to ICU with sodium phenylbutyrate: a preliminary study
Fundamental&Clinical Pharmacology,Volume 32, Issue 2, Page 209-215, April 2018. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 14, 2017 Category: Drugs & Pharmacology Source Type: research
---
Fundamental&Clinical Pharmacology, Ahead of Print. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 12, 2017 Category: Drugs & Pharmacology Source Type: research
Comparative study of amlodipine vs. cilnidipine for the prevention of hepatic ischemia ‐reperfusion injury in rat model
We examined the effect of pretreatment with AML or CIL (100 μg/kg i.p.) 45 min before induction of 60 min of liver ischemia followed by reperfusion, on oxidative stress markers, liver enzymes, serum tumor necrosis factor‐α, interleukin‐1β, apoptosis markers, and nuclear factor KB after 6 and 24 h of hepatic reperfusion. Both drugs significantly ameliorated biochemical and histological markers of hepatic I/R injury, but protection with CIL was more significant at the 6‐h time point where protection with AML outlasted that of CIL. Both drugs offered significant protection against hepatic I/R damage, but the protecti...
Source: Fundamental and Clinical Pharmacology - December 12, 2017 Category: Drugs & Pharmacology Authors: Abdel ‐Motaal Fouda, Amany R. Youssef, Osama Sharaf Eldin Tags: Original Article Source Type: research
An observational study of benzodiazepine prescription during inpatient alcohol detoxification for patients with vs. without chronic pretreatment with high ‐dosage baclofen
Fundamental&Clinical Pharmacology,Volume 32, Issue 2, Page 200-205, April 2018. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 10, 2017 Category: Drugs & Pharmacology Source Type: research
---
Fundamental&Clinical Pharmacology, Ahead of Print. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 6, 2017 Category: Drugs & Pharmacology Source Type: research
On ‐the‐ground application of the ‘temporary recommendation for use’ regulatory measure on off‐label use of baclofen for alcohol dependence in France: a regional survey of community pharmacies
Abstract
The ‘temporary recommendation for use’ (TRU) is a French novel regulatory measure for off‐label drug. The first TRU to be issued by the French drug agency (in March 2014) pertained to the off‐label use of baclofen for alcohol dependence (AD). We performed a questionnaire‐based survey of the on‐the‐ground application of the baclofen TRU among community pharmacies in northern France. A pharmacist from 70 of the 219 pharmacies contacted (response rate: 32.0%) completed the questionnaire. The mean ± standard deviation number of off‐label baclofen prescriptions for AD was 2.3 ± 2.2 per pharmacy per mo...
Source: Fundamental and Clinical Pharmacology - December 6, 2017 Category: Drugs & Pharmacology Authors: Marine Auffret, Benjamin Rolland, Anne ‐Sylvie Caous, Louise Gaboriau, Sylvie Deheul, Régis Bordet, Sophie Gautier Tags: Original Article Source Type: research
Inhibition of spinal p38 MAPK prevents articular neutrophil infiltration in experimental arthritis via sympathetic activation
Fundamental&Clinical Pharmacology,Volume 32, Issue 2, Page 155-162, April 2018. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 5, 2017 Category: Drugs & Pharmacology Source Type: research
Aging and hypertension decrease endothelial NO ‐related dilating function and gamma‐glutamyltransferase activity but not S‐nitrosoglutathione‐induced aortic vasodilation
This article is protected by copyright. All rights reserved. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 1, 2017 Category: Drugs & Pharmacology Authors: Caroline Perrin ‐Sarrado, Fatima Dahboul, Pierre Leroy, Isabelle Lartaud Tags: Original Article Source Type: research
Possible role of CYP2B6 genetic polymorphisms in ifosfamide ‐induced encephalopathy: report of three cases
This article is protected by copyright. All rights reserved. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 1, 2017 Category: Drugs & Pharmacology Authors: Thomas Duflot, Aude Marie ‐Cardine, Céline Verstuyft, Bruno Filhon, Tony Pereira, Nathalie Massy Guillemant, Robinson Joannidès, Jérémy Bellien, Fabien Lamoureux Tags: Case Report Source Type: research
Continuous intravenous vancomycin in children with normal renal function hospitalized in hematology ‐oncology: prospective validation of a dosing regimen optimizing steady‐state concentration
This study assessed the prospective validation of this age‐based nomogram and the influence on Css attainment of variables as the gender, underlying disease (oncology or hematology), and hematopoietic stem cell transplantation (HSCT) before receiving vancomycin therapy.
A total of 94 patients aged from 4.3 months to 17.9 years old with normal renal function were eligible for the prospective validation. Fifty‐five of those patients (58.5%) achieved the target range of vancomycin Css. There was no significant difference between age groups (p=0.816) and no influence of gender (p=0.500). There was a non‐significant trend...
Source: Fundamental and Clinical Pharmacology - December 1, 2017 Category: Drugs & Pharmacology Authors: Delphine Hoegy, Sylvain Goutelle, Nathalie Garnier, C écile Rénard, Cécile Faure‐Conter, Christophe Bergeron, Yves Bertrand, Nathalie Bleyzac Tags: Original Article Source Type: research
Adverse drug reactions of analgesic medicines: analysis of the Romanian pharmacovigilance database
This article is protected by copyright. All rights reserved. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 1, 2017 Category: Drugs & Pharmacology Authors: Irina Cazacu, Roxana Stroe, Roxana Dondera, Cristina Mogosan, Fran çoise Haramburu, Annie Fourrier‐Réglat, Felicia Loghin Tags: Original Article Source Type: research
Protective effect of fenofibrate against ischemia ‐reperfusion induced cardiac arrhythmias in isolated rat hearts
This article is protected by copyright. All rights reserved. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 1, 2017 Category: Drugs & Pharmacology Authors: Ishfaq A. Bukhari, Abdulrahman A. Almotrefi, Osama Y. Mohamed, Abeer A. Al ‐Masri, Saeed Ahmed Sheikh Tags: Original Article Source Type: research
Treating hepatic encephalopathy in cirrhotic patients admitted to ICU with sodium phenylbutyrate: a preliminary study
This article is protected by copyright. All rights reserved. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 1, 2017 Category: Drugs & Pharmacology Authors: Nicolas Weiss, Simona Tripon, Marion Lodey, Elsa Guiller, Helga Junot, Denis Monneret, Julien Mayaux, H élène Brisson, Maxime Mallet, Marika Rudler, Françoise Imbert‐Bismut, Dominique Thabut, Tags: Original Article Source Type: research
An observational study of benzodiazepine prescription during inpatient alcohol detoxification for patients with versus without chronic pretreatment with high dosage baclofen
Conclusion: steady‐state high dose baclofen before an inpatient alcohol cessation hospitalization does not lower the needed benzodiazepine dose in the management of alcohol withdrawal symptoms.
This article is protected by copyright. All rights reserved. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 1, 2017 Category: Drugs & Pharmacology Authors: Laura Martinez, Florence Vorspan, Xavier Decl èves, Julien Azuar, Maeva Fortias, Franck Questel, Alexandra Dereux, Leslie Grichy, Hélène Barreteau, Frank Bellivier, Jean‐Pierre Lépine, Vanessa Bloch Tags: Original Article Source Type: research
Inhibition of spinal p38 MAPK prevents articular neutrophil infiltration in experimental arthritis via sympathetic activation
In conclusion, our results suggest that pharmacological strategies involving the modulation of spinal p38 MAPK circuit can prevent joint inflammation via sympathetic networks and beta‐adrenoceptors activation.
This article is protected by copyright. All rights reserved. (Source: Fundamental and Clinical Pharmacology)
Source: Fundamental and Clinical Pharmacology - December 1, 2017 Category: Drugs & Pharmacology Authors: Alexandre Kanashiro, Marcelo Franchin, Gabriel Shimizu Bassi, D ênis Augusto Reis‐Santana, Thiago Mattar Cunha, Fernando Queiróz Cunha, Luis Ulloa, Gerson Jonathan Rodrigues Tags: Original Article Source Type: research
