Inhibition of spinal p38 MAPK prevents articular neutrophil infiltration in experimental arthritis via sympathetic activation

In conclusion, our results suggest that pharmacological strategies involving the modulation of spinal p38 MAPK circuit can prevent joint inflammation via sympathetic networks and beta‐adrenoceptors activation.
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Source: Fundamental and Clinical Pharmacology - December 1, 2017 Category: Drugs & Pharmacology Authors: Alexandre Kanashiro, Marcelo Franchin, Gabriel Shimizu Bassi, D ênis Augusto Reis‐Santana, Thiago Mattar Cunha, Fernando Queiróz Cunha, Luis Ulloa, Gerson Jonathan Rodrigues Tags: Original Article Source Type: research