Tumor microenvironment and noncoding RNAs as co ‐drivers of epithelial–mesenchymal transition and cancer metastasis
This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - July 1, 2017 Category: Molecular Biology Authors: Kinan Drak Alsibai, Didier Meseure Tags: Reviews Source Type: research
A morphology independent approach for identifying dividing adult neural stem cells in the mouse hippocampus
Conclusion
These findings provide a simple and accurate way to quantify dividing AH‐NSCs in vivo using a morphology independent approach that will facilitate studies into neurogenesis within the hippocampal stem cell niche of the adult brain. This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - July 1, 2017 Category: Molecular Biology Authors: Lachlan Harris, Oressia Zalucki, Sabrina Oishi, Thomas H. Burne, Dhanisha J. Jhaveri, Michael Piper Tags: Techniques Source Type: research
Transcriptional changes in chick wing bud polarization induced by retinoic acid
Conclusions: Our findings reveal how retinoic acid and Shh signalling could co‐operate in antero‐posterior patterning of the limb. This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - July 1, 2017 Category: Molecular Biology Authors: Joseph Pickering, Neha Wali, Matthew Towers Tags: Research Article Source Type: research
Separate and coincident expression of Hes1 and Hes5 in the developing mouse eye
Conclusions: Hes5‐GFP BAC transgenic mice are useful for identifying Hes5‐expressing cells. Although Hes5‐GFP and Hes1 are coexpressed in particular developmental contexts, we also noted cohorts of lens or retinal cells expressing just one factor. The dynamic Hes5‐GFP expression pattern, coupled with its derepressed expression in Hes1 mutants, suggests that this transgene contains the relevant cis‐regulatory elements that regulate endogenous Hes5 in the mouse lens and retina. This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - July 1, 2017 Category: Molecular Biology Authors: Amy N. Riesenberg, Kevin W. Conley, Tien T. Le, Nadean L. Brown Tags: Patterns & Phenotypes Source Type: research
Influences of Placental Growth Factor on Mouse Retinal Vascular Development
Conclusions: Overall, PGF has a role in retinal vascular angiogenesis and vessel organization during development but does not affect retinal vessel adaptations in adult females during pregnancy. This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - June 24, 2017 Category: Molecular Biology Authors: Vanessa R. Kay, Chandrakant Tayade, Peter Carmeliet, B. Anne Croy Tags: Patterns & Phenotypes Source Type: research
Epithelial mesenchymal transition (EMT), a spectrum of states: role in lung development, homeostasis and disease
This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - June 24, 2017 Category: Molecular Biology Authors: Mohit Kumar Jolly, Chris Ward, Mathew Suji Eapen, Stephen Myers, Oskar Hallgren, Herbert Levine, Sukhwinder Singh Sohal Tags: Reviews Source Type: research
Cell lineage tracing in the retina: Could material transfer distort conclusions?
This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - June 23, 2017 Category: Molecular Biology Authors: Camille Boudreau ‐Pinsonneault, Michel Cayouette Tags: Critical Commentaries Source Type: research
IRF6 expression in basal epithelium partially rescues Irf6 knockout mice
Conclusion: Together, these data suggest that targeted expression of IRF6 can significantly reduce disease severity, but that a minimum level of Irf6 in both periderm and basal epithelial cells is necessary for orofacial development. Therefore, homologous human and mouse phenotypes are observed for IRF6, IKKA and RIPK4. In this work, we show that altering the expression level of IRF6 dramatically modified this phenotype in utero. This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - June 23, 2017 Category: Molecular Biology Authors: Youssef A. Kousa, Dina Moussa, Brian C. Schutte Tags: Research Article Source Type: research
Mitochondrial dynamics in the regulation of neurogenesis: From development to the adult brain
This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - June 23, 2017 Category: Molecular Biology Authors: Mireille Khacho, Ruth S. Slack Tags: Reviews Source Type: research
Maximizing functional axon repair in the injured CNS – lessons from neuronal development
This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - June 23, 2017 Category: Molecular Biology Authors: Andrew Kaplan, Mardja Bueno, Luyang Hua, Alyson E. Fournier Tags: Critical Commentaries Source Type: research
RUNX2 ‐I is an early regulator of epithelial‐mesenchymal cell transition in the chick embryo
Conclusions: This data introduces the RUNX2‐I isoform as a critical early transcription factor mediating EMT in the developing heart after induction by TGFβ2. Its expression in tumor tissue suggests a similar role for RUNX2 in the EMT of metastasis. This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - June 20, 2017 Category: Molecular Biology Authors: Andre L.P. Tavares, Jessie A. Brown, Emily C. Ulrich, Katerina Dvorak, Raymond B. Runyan Tags: Research Article Source Type: research
Issue Information
COVER PHOTOGRAPH: Amplification of the FGF10+ cell lineage in an embryonic lung explant in response to recombinant FGF9 treatment; branching epithelium evident on the left and dilated epithelium on the right. From: Ex vivo analysis of the contribution of FGF10+ cells to airway smooth muscle cell formation during early lung development; Elie El Agha, Vahid Kheirollahi, Alena Moiseenko, Werner Seeger and Saverio Bellusci. Developmental Dynamics: 246:530–537. (Source: Developmental Dynamics)
Source: Developmental Dynamics - June 15, 2017 Category: Molecular Biology Tags: Issue Information Source Type: research
Cells from subcutaneous tissues contribute to scarless skin regeneration in Xenopus laevis froglets
Conclusions: Cells derived from subcutaneous tissues, at least in the trunk region, contribute to and may be essential for skin regeneration. Characterizing the subcutaneous tissue–derived cells that contribute to skin regeneration in amphibians may lead to the induction of cells that can regenerate complete skin structures without scarring in mammals. Developmental Dynamics, 2017. © 2017 Wiley Periodicals, Inc. (Source: Developmental Dynamics)
Source: Developmental Dynamics - June 15, 2017 Category: Molecular Biology Authors: Rina Otsuka ‐Yamaguchi, Aiko Kawasumi‐Kita, Nanako Kudo, Yumi Izutsu, Koji Tamura, Hitoshi Yokoyama Tags: Research Article Source Type: research
A global community effort to decipher the unique biology of annual killifish
This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - June 12, 2017 Category: Molecular Biology Authors: Nibia Berois, Graciela Garcia, Rafael Omar de S á Tags: Reviews Source Type: research
Transmission Electron Microscopy of Zebrafish Spinal Motor Nerve Roots
Conclusions: We developed an efficient protocol for locating spinal motor nerves in adult zebrafish to allow for ultrastructural characterization. Although our work focuses on spinal motor nerves, this protocol may be useful for efficiently identifying other discrete, repeated structures within the developing and mature nervous system that are difficult to find via traditional, whole organism TEM processing. This article is protected by copyright. All rights reserved. (Source: Developmental Dynamics)
Source: Developmental Dynamics - June 9, 2017 Category: Molecular Biology Authors: Angela D. Morris, Alev Erisir, Stacey J. Criswell, Sarah Kucenas Tags: Techniques Source Type: research
