Updates for Chest Tumors
(Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - July 12, 2018 Category: Cancer & Oncology Source Type: research
Meet Our Editorial Board Member
(Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - July 12, 2018 Category: Cancer & Oncology Source Type: research
Papain Loaded Solid Lipid Nanoparticles for Colorectal Cancer Therapy
Conclusion: In this research, we successfully formulated the P-SLN for the treatment of colorectal cancer therapy. We investigate the various formulation parameters, drug release profile and cytotoxic efficacy of P-SLN. Upon successful completion of this work, P-SLNs delivery system is predictable to produce enhanced cytotoxic efficacy against HT-29 colorectal cancer cells. The papain loaded SLNs can potentially be utilized as a drug delivery system for the treatment of colorectal cancer. In future, we will explore further to investigate the mechanism of anticancer activity and clinical investigation of P-SLN. (Source: Cur...
Source: Current Cancer Therapy Reviews - February 28, 2018 Category: Cancer & Oncology Source Type: research
Stereotactic Body Radiation Therapy in Head and Neck Squamous Cell Carcinoma: Science or Art?
Conclusion: The use of stereotactic body radiotherapy is still evolving and multiple studies are needed to optimize the dose fractionation of SBRT and its integration with systemic therapy. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 28, 2018 Category: Cancer & Oncology Source Type: research
Role of Stereotactic Radiosurgery in the Management of Brain and Spine Metastases
Conclusion: While the data support its use, there needs to be continued research with improved technology, on the use of radiosurgery for larger brain metastases, and on the toxicities of radiosurgery and its management. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 28, 2018 Category: Cancer & Oncology Source Type: research
The Role of Stereotactic Body Radiation Therapy in Pancreatic Cancer
Conclusion: SBRT represents an emerging treatment option for patients to improve local control through delivery of ablative, high-dose radiation while reducing radiation treatment time as compared to conventionally fractionated chemoradiation. Further studies are needed to explore the full potential and toxicities of SBRT in pancreatic cancer. The importance of technical considerations in this modality cannot be overstated. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 28, 2018 Category: Cancer & Oncology Source Type: research
Stereotactic Body Radiotherapy (SBRT) in the Management of Clinically Localized Prostate Cancer: Where are We Now?
Background: Stereotactic body radiotherapy (SBRT) is a recent addition to the armamentarium for treating clinically localized prostate cancer. SBRT is a special form of image-guided radiotherapy (IGRT) that involves the delivery of a small number of very high-dose fractions (e.g. 35 to 40 Gy, in 4 to 5 fractions). The slow-growing nature of prostate adenocarcinoma is thought to be associated to a low α[alpha]/β[beta] ratio of ~1.5, that is believed to confer a preferential sensitivity to ultra-hypofractionation. Literature documenting excellent long-term outcomes and relatively low toxicity with high dose-rate (H...
Source: Current Cancer Therapy Reviews - February 28, 2018 Category: Cancer & Oncology Source Type: research
SBRT for Liver Cancer
Conclusion: Stereotactic body radiation therapy is a non-invasive, effective and welltolerated treatment modality for patients with liver cancer. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 28, 2018 Category: Cancer & Oncology Source Type: research
Editorial: The Role of Stereotactic Body Radiotherapy: A Review
(Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 28, 2018 Category: Cancer & Oncology Source Type: research
Preface
(Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 28, 2018 Category: Cancer & Oncology Source Type: research
Meet Our Editorial Board Member
(Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 28, 2018 Category: Cancer & Oncology Source Type: research
Acknowledgements to Reviewers
(Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - November 15, 2017 Category: Cancer & Oncology Source Type: research
In Silico Study and Cytotoxicity of the Synthesized Open-chain Analogues of Antimycin A3 Against HEP-2 Laryngeal Cancer Cells
Conclusion: Open-chain analogues of antimycin A3 were successfully synthesized in a good yield from Boc-L-Threonine by esterification, amidation, and Sharpless asymmetric dihydroxylation. Consistent with in silico study, the analogues exhibited a greater anticancer activity against laryngeal HEP-2 cells than the original antimycin A3 with IC50 ranging of 31.6 µM to 46.3 µM. Our results clearly demonstrate that the open-chain analogues of antimycin A3 as a promising candidates of new anti-laryngeal cancer agents. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - November 15, 2017 Category: Cancer & Oncology Source Type: research
Emerging Family of Protein-protein Interaction Inhibitors Targeting PD-1 Checkpoint Pathway
Conclusion: The potential use of PD-1 checkpoint inhibitor alone or in combination with other agents is substantial, and will further reveal the important role of PD-1 pathway in immunomodulation and disease control. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - November 15, 2017 Category: Cancer & Oncology Source Type: research
PDE5 Inhibitors Offer Novel Mechanisms in Combination and Solo Cancer Therapy
Conclusion: This review offers insights into the various mechanisms by which PDE5 inhibitors exert their antineoplastic actions. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - November 15, 2017 Category: Cancer & Oncology Source Type: research
