Roles of Tumor Microenvironment in Hepatocelluar Carcinoma
Hepatocellular carcinoma (HCC) is one of the most malignant human cancers, with a high mortality rate worldwide despite its early diagnosis in patients and improvement in therapeutic technology. Most cases of liver cancer show a strong resistance to anticancer therapy. Moreover, liver cancer patients generally have poor tolerance to chemotherapy due to liver dysfunction. In these situations, liver-targeting drugs with fewer side effects and a high efficacy are urgently needed during drug discovery for liver cancer. Researchers have aimed to derive target genes and drug candidates for HCC; however, the development of target...
Source: Current Cancer Therapy Reviews - December 20, 2015 Category: Cancer & Oncology Source Type: research
Primary Management of Metastatic Colorectal Cancer with Bevacizumab. Review Article Focusing on Efficacy
The cancer originated from large bowel represents a widespread cancer along the world and a considerable percentage of new cases are diagnosed with distant disease. Recently, the detection of “clever” medicaments such as focused therapy was the outcome of an improved comprehension of the procedures that transform physiological tissues to tumor. The family of focused medication includes medicaments that specifically affect specific molecular routes implicated in the production of the tumor and its development. The new natural substances aim at inhibiting the procedure of angiogenesis which is fundamental for cancer deve...
Source: Current Cancer Therapy Reviews - December 20, 2015 Category: Cancer & Oncology Source Type: research
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(Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - December 20, 2015 Category: Cancer & Oncology Source Type: research
