Combinatorial Use of DNA Ligase Inhibitor L189 and Temozolomide Potentiates Cell Growth Arrest in HeLa
Conclusions: These results underscore the combinatorial treatment using TMZ and L189 to bring desirable cancer cell growth arrest and future molecular study to dissect out the participating pathways. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 22, 2019 Category: Cancer & Oncology Source Type: research

Prerequisite of a Holistic Blend of Traditional and Modern Approaches of Cancer Management
Conclusion: Both genetic as well as environmental factors have shown their linkage with cancer. Substantial advancements in the field of targeted therapies have opened new horizons for the cancer patients. To fight with this grave situation, a combination of ancient and modern medicinal systems seems to be the need of the hour. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 22, 2019 Category: Cancer & Oncology Source Type: research

Do we Need Maintenance Chemotherapy in Advanced NSCLC in the Era of Immune and Targeted Therapy?
Conclusion: Maintenance therapy in NSCLC continues to be an important therapeutic line to improve outcome in patients with metastatic and recurrent disease. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 22, 2019 Category: Cancer & Oncology Source Type: research

Cancer Chemotherapy by Novel Bio-active Natural Products: Looking Towards the Future
Conclusion: Current review has been highlighted on the novel medicinal agents from plant sources have potential effects against many types of cancer, which have been supported by clinical trials. The main findings of these active novel medicinal agents were also summarized and discussed here. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 22, 2019 Category: Cancer & Oncology Source Type: research

Impact of Probiotics and Prebiotics on Colon Cancer: Mechanistic Insights and Future Approaches
Colon cancer is one of the most common and most diagnosed types of cancer. It is a major cause of increased rate of morbidity and mortality across the globe. Currently, the focus has been shifted towards natural remedies for the treatment of colon cancer. These new methods of treatment include prebiotics and probiotics, as they offer great potential for alleviating symptoms of cancer. These are more promising and have lesser side effects than existing medications. Probiotics are living organisms which confer health benefits when ingested into adequate amounts. Prebiotics are non-digestible ingredients which promote the gro...
Source: Current Cancer Therapy Reviews - February 22, 2019 Category: Cancer & Oncology Source Type: research

Comparative Analysis of DNA Motif Discovery Algorithms: A Systemic Review
Conclusion: Nature-inspired algorithms and many of combinatorial algorithms are recently proposed to overcome the problems of consensus and probabilistic approaches. This paper presents a general classification of motif discovery algorithms with new sub-categories. It also presents a summary comparison between them. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 22, 2019 Category: Cancer & Oncology Source Type: research

The Pure Guy – The Scientist
(Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 22, 2019 Category: Cancer & Oncology Source Type: research

Meet our Editorial Board Member
(Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - February 22, 2019 Category: Cancer & Oncology Source Type: research

Acknowledgements to Reviewers
(Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - July 12, 2018 Category: Cancer & Oncology Source Type: research

End of Life Issues – Hong Kong, France and Canada
Conclusion: Different Canadian hospitals developed practical guidelines and procedures by 2017 already. Ramifications of MAID will be discussed in this review. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - July 12, 2018 Category: Cancer & Oncology Source Type: research

Palliative Care for Chest Tumors – Hong Kong, France and Canada
In Asia, North America and Europe, lung cancer remains one of the top contributors to cancer-related death. Oncology training programs span 4-5 years and palliative care fellowship is around 2 years. However, the multi-disciplinary conference is increasingly viewed as preferable to assist with decision making in most modern centers. Palliative care for lung cancer likewise differs between regions. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - July 12, 2018 Category: Cancer & Oncology Source Type: research

Palliative Radiation of Chest Tumors
Palliation may be the goal of care for some patients with intra-thoracic lung cancer. Factors such as the extent of disease, comorbidities, performance status, or symptom burden, may indicate that patients are unsuitable for more aggressive approaches with a curative intent. A palliative treatment plan implies a focus on the effective relief and control of symptoms, while preserving both the quality and quantity of life. Therapeutic measures may include palliative radiotherapy, palliative chemotherapy, or other forms of systemic treatment. In addition, certain interventional procedures may be used to achieve symptom pallia...
Source: Current Cancer Therapy Reviews - July 12, 2018 Category: Cancer & Oncology Source Type: research

Lung Cancer Brachytherapy
Conclusion: In spite of the rapid development of external beam radiation therapy brachytherapy continues to remain an important mode of therapy and is often a default treatment when external beam radiation option is limited. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - July 12, 2018 Category: Cancer & Oncology Source Type: research

Systemic Treatment of Chest Tumors: Highlighting Some Differences Between Eastern and Western Countries
Conclusion: The approaches of this review are to highlight the recent management advances and contrast the differences of treatment practice between Western and Asian countries. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - July 12, 2018 Category: Cancer & Oncology Source Type: research

Current Overview of Lung Cancer from Pathology, Screening to Treatment
Conclusion: This article provides a brief current overview of literature pertaining to the role of radiation therapy in the management of lung cancer. (Source: Current Cancer Therapy Reviews)
Source: Current Cancer Therapy Reviews - July 12, 2018 Category: Cancer & Oncology Source Type: research