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Artificial cervical disc replacement with the Prestige-LP prosthesis for the treatment of non-contiguous 2-level cervical degenerative disc disease: A minimum 24-month follow-up
Anterior cervical discectomy and fusion(ACDF) is widely accepted and considered a safe and effective treatment for single- or multilevel cervical degenerative disc disease, due to its high fusion rate and excellent clinical outcomes [1,2]. Although such a procedure is significant in terms of resolving symptoms, improving nerve function and maintaining or restoring the cervical stability, the loss of range of motion and the acceleration of adjacent segment degeneration (ASD) raise concerns regarding the long-term morbidity, which leads to subsequent surgery [3,4]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - November 16, 2016 Category: Neurosurgery Authors: Tingkui Wu, Beiyu Wang, Ding Chen, Yang Meng, Jigang Lou, Yi Yang, Hao Liu Source Type: research

Effects of Cerebrolysin on Functional Recovery in Patients with Severe Disability after Traumatic Brain Injury: A Historical Cohort Study
Traumatic brain injury (TBI) is the leading cause of mortality and morbidity among young age groups worldwide being associated with high healthcare, social and economic burden [1,2]. According to United States statistics, the cost of TBI is approximately 48.3-76.3 billion dollars annually [3]. Center for Disease Control (CDC) has reported that the incidence of TBI is 1.7 million annually with 52,000 deaths and over 250,000 hospitalizations in US alone [3]. The incidence rates are even higher in developing countries with a TBI with associated mortality rate of 37.7 to 48.4 per 100,000 populations per year [4,5]. (Source: Cl...
Source: Clinical Neurology and Neurosurgery - November 14, 2016 Category: Neurosurgery Authors: Hosseinali Khalili, Amin Niakan, Fariborz Ghaffarpasand Source Type: research

Micro vs. Macrodiscectomy: Does Use of the Microscope Reduce Complication Rates?
The concept of microsurgery has revolutionized surgical techniques across multiple surgical specialties. Over three decades ago neurosurgeons were adapting microsurgical techniques to many pathologies in their cranial practice, and at the 1969 American Association of Neurologic Surgeons (AANS) and the Congress of Neurologic Surgeons (CNS) meeting microneurosurgical instrument prototypes and intraoperative microscopes debuted. These tools became staples of the neurosurgical operative armamentarium in subsequent decades [1]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - November 12, 2016 Category: Neurosurgery Authors: Meghan E. Murphy, Jeffrey S. Hakim, Panagiotis Kerezoudis, Mohammed Ali Alvi, Daniel S. Ubl, Elizabeth B. Habermann, Mohamad Bydon Source Type: research

Simplest radiological measurement related to clinical success in endoscopic third ventriculostomy
Endoscopic third ventriculostomy (ETV) is a popular alternative to cerebrospinal fluid (CSF) shunting in selected cases [8,10]. The success of ETV procedures can be judged either with clinical outcomes or with changes in patients ’ radiological findings. Clinical outcomes can be judged relatively straightforward. A patient who has benefited from the intervention is a success. Many studies have linked clinical parameters such as age, underlying etiology and treating center volume with success [2,9,10,12]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - November 10, 2016 Category: Neurosurgery Authors: Alp Özgün BÖRCEK, Murat UÇAR, Burak KARAASLAN Source Type: research

Bone scintigraphy for the diagnosis of the responsible level of osteoporotic vertebral compression fractures in percutaneous balloon kyphoplasty
Vertebral compression fracture (VCF) is the compression fracture of the vertebral body that causes deterioration in the activities of daily living (ADL) and quality of life because of the intolerable severe back pain. In addition, the prevalence of osteoporotic VCF steadily increases with increasing age, resulting in increased mortality and morbidity as well [1 –4]. The conservative treatment of VCFs includes bed rest and pain medication. Vertebroplasty (VP) and balloon kyphoplasty (BKP) serve as the second line therapy to patients with severe bone pain, disability, and vertebral deformity. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - November 10, 2016 Category: Neurosurgery Authors: Toshiyuki Okazaki, Hiroshi Nakagawa, Kenji Yagi, Hitoshi Hayase, Shinji Nagahiro, Koji Saito Source Type: research

Spinal Cordectomy: A New Hope for Morbid Spinal Conditions
Spinal cordectomy is a neurosurgical procedure that involves transection of the injured spinal cord. Since its inception in 1916, it has been a controversial form of treatment for morbid spinal conditions. Cordectomy is considered a final option for various progressive spinal pathologies. The published literature does not clearly answer the question of whether it is a solution of a problem or it creates more harm to the patient. According to the literature, this procedure has been used for various spinal cord disorders including spinal cord trauma or spinal cord tumor or even in congenital anomalies of the spinal cord. (So...
Source: Clinical Neurology and Neurosurgery - November 9, 2016 Category: Neurosurgery Authors: Subhas K. Konar, Tanmoy K. Maiti, Shyamal C. Bir, Anil Nanda Tags: Review Source Type: research

Sensory-motor axonal polyneuropathy involving cranial nerves: an uncommon manifestation of disulfiram toxicity
Disulfiram (tetraethylthiuram disulfide) has been used for the treatment of alcohol dependence for more than fifty years [1]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - November 9, 2016 Category: Neurosurgery Authors: Telma Santos, Ant ónio Martins Campos, Hugo Morais Tags: Case Report Source Type: research

Marked EEG worsening following Levetiracetam overdose: How a pharmacological issue can confound coma prognosis
Levetiracetam (LEV) is an anti-epileptic drug with a simple pharmacokinetic profile, a quick efficacy after a rapid intravenous administration and a claimed good tolerance. Side effects such as somnolence, dizziness and psychosis have been reported during chronic LEV treatment for conscious patients with normal dose. Only few cases of LEV overdose are reported and these are usually associated with mild symptoms, suggesting that the safety of this treatment could be extended to the acute phase of brain injury [1]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - November 7, 2016 Category: Neurosurgery Authors: Baptiste Bouchier, Genevi ève Demarquay, Claude Guérin, Nathalie André-Obadia, Florent Gobert Tags: Case Report Source Type: research

Surgical Treatment of Unruptured Middle Cerebral Artery Aneurysms: Complication Avoidance
Intracranial aneurysms arising from the middle cerebral artery (MCA) are anatomically favorable lesions for surgical clipping. Ischemic complications (IC) secondary to compromise of an M2 trunk or perforator branch during surgical treatment of MCA aneurysms can cause substantial neurological morbidity and long-term functional impairment. The sequelae of these postoperative complications can be particularly devastating for patients harboring unruptured aneurysms, who are frequently minimally symptomatic or entirely asymptomatic. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - November 5, 2016 Category: Neurosurgery Authors: Dale Ding Source Type: research

Corrigendum to “Simultaneous multisystem surgery: An important capability for the civilian trauma hospital” [Clin. Neurol. Neurosurg. 148 (2016) 13–16]
The authors regret that final author name has been listed incorrectly. The final author name is Rosenfeld J.V. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - November 2, 2016 Category: Neurosurgery Authors: Justin M. Moore, Piers A.W. Thomas, Russell L. Gruen, Patrick Chan, Jeffrey V. Rosenfeld Tags: Corrigendum Source Type: research

Biomarkers related with seizure risk in glioma patients: a systematic review
Seizures are common symptoms in patients with glioma and whereas 46% –90% of patients with grade II glioma reportedly experience epileptic seizures before surgery, 42%–71% and 29%–52% of grade III and IV glioma patients, respectively, experience seizures [1–11].Moreover, the incidence of seizures reportedly depends on tumour grade and type [12,13] and increas ed risks of seizure have been observed in patients with gliomas in regions of the temporal lobe [14].Although glioma-related seizures have favourable effects on the overall survival of glioma patients [15–17], undesirable influences on quality of life qualit...
Source: Clinical Neurology and Neurosurgery - November 1, 2016 Category: Neurosurgery Authors: Xing-wang Zhou, Xiang Wang, Yuan Yang, Jie-wen Luo, Hui Dong, Yan-hui Liu, Qing Mao Source Type: research

Anterior interosseous nerve and posterior interosseous nerve involvement in neuralgic amyotrophy
The aim of this study was to gain a better understanding of anterior interosseous nerve and posterior interosseous nerve involvement in neuralgic amyotrophy. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - November 1, 2016 Category: Neurosurgery Authors: Mao Akane, Katsuyuki Iwatsuki, Masahiro Tatebe, Takanobu Nishizuka, Shigeru Kurimoto, Michiro Yamamoto, Hitoshi Hirata Source Type: research

Spinal Sagittal Balance and Spinopelvic Parameters in Patients with Degenerative Lumbar Spinal Stenosis; A Comparative Study
Lumbar spinal stenosis is the most common lumbar degenerative disease [1]. Spinal stenosis is a narrowing of the vertebral canal that may lead to compression of the spinal nerves or nerve roots, especially in the area of the lumbar vertebrae [2,3]. Lumbar spinal canal stenosis is among the most common morbidities of the aging population which is associated with high social and economic burden [4]. The prevalence of relative and absolute acquired lumbar canal stenosis has been reported as 22.5% and 7.3% of the normal population, respectively [5]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 30, 2016 Category: Neurosurgery Authors: Majid Reza Farrokhi, Ali Haghnegahdar, Hamid Rezaee, Mohammad Reza Sharifi Rad Source Type: research

Revision surgery for cervical artificial disc: surgical technique and clinical results
Cervical disc herniation was treated with ACDF for the last decades in patients that have not responded to non-surgical treatment options and suffered from significant affected quality of life and ability to function [1]. As ACDF stands for elimination of motion at the operated cervical level resulting in decreased neck mobility and risk of adjacent segment degeneration, alternative surgical strategies were warranted. This led to the development of cervical disc replacement and implantation of the first cervical artificial disc in 1960s [2,3]. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 30, 2016 Category: Neurosurgery Authors: J. Onken, A. Reinke, J. Radke, T. Finger, S. Bayerl, P. Vajkoczy, B. Meyer Source Type: research

Validity assessment of grading scales predicting complications from embolization of cerebral arteriovenous malformations
The recent Randomized Trial of Unruptured Brain Arteriovenous Malformations (ARUBA) has spurred significant debate amongst neurointerventionalists regarding the precise role of invasive procedures for the treatment of cerebral arteriovenous malformations (AVMs). It found that the risk of stroke and death was nearly three-fold more in patients presenting with unruptured AVMs who were treated via intervention and medical management as compared with medical management alone [1]. One of these invasive procedures, endovascular embolization, is commonly performed as an adjunct to surgical resection. (Source: Clinical Neurology and Neurosurgery)
Source: Clinical Neurology and Neurosurgery - October 28, 2016 Category: Neurosurgery Authors: Raghav Gupta, Nimer Adeeb, Justin M. Moore, Rouzbeh Motiei-Langroudi, Christoph J. Griessenauer, Apar S. Patel, Christopher S. Ogilvy, Ajith J. Thomas Tags: Full length article Source Type: research