Marked EEG worsening following Levetiracetam overdose: How a pharmacological issue can confound coma prognosis

Levetiracetam (LEV) is an anti-epileptic drug with a simple pharmacokinetic profile, a quick efficacy after a rapid intravenous administration and a claimed good tolerance. Side effects such as somnolence, dizziness and psychosis have been reported during chronic LEV treatment for conscious patients with normal dose. Only few cases of LEV overdose are reported and these are usually associated with mild symptoms, suggesting that the safety of this treatment could be extended to the acute phase of brain injury [1].
Source: Clinical Neurology and Neurosurgery - Category: Neurosurgery Authors: Tags: Case Report Source Type: research