Chinese Journal of Analytical Chemistry 
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.pH Resistant Ratiometric Measurement of Nicotinamide Adenine Dinucleotide Levels by Time-resolved Fluorescence Spectroscopy
Publication date: January 2019Source: Chinese Journal of Analytical Chemistry, Volume 47, Issue 1Author(s): Lei LI, Jia-Sheng ZHOU, Peng WANG, Chao-Qun MA, Zhuo-Wei ZHU, Jiao GU, Chun ZHU, Guo-Qing CHEN, San-Jun ZHANG, Jian-Hua XUAbstractCircular permutation fluorescent protein is a novel method to construct biosensors. The ratio of two excitation channels is employed to quantitatively calibrate the level of analysts. SoNar is one of them, which can be used to monitor cellular NADH/NAD+ levels. However, the 490 nm excitation channel of these biosensors is sensitive to pH environments, which is negative in real applications...
Source: Chinese Journal of Analytical Chemistry - January 10, 2019 Category: Chemistry Source Type: research
Applications of Modular Microfluidics Technology
Publication date: December 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 12Author(s): Yi-Qiang FAN, Hong-Liang WANG, Ke-Xin GAO, Jing-Ji LIU, Dong-Ping CHAI, Ya-Jun ZHANGAbstractMicrofluidics has been widely used in the life science, analytical chemistry, environmental science and other fields in the recent years. Traditional microfluidics systems usually use a highly integrated system with multiple components for handling the fluid in the micro/nano scale. The design and fabrication of integrated microfluidics usually require highly sophisticated instruments and operation professionals. With the ex...
Source: Chinese Journal of Analytical Chemistry - December 8, 2018 Category: Chemistry Source Type: research
Structure and Performance of Polygonal Electrode Linear Ion Trap
This study investigated the relationship between the electric field distribution and the ion trap structures, and the performances of PeLIT through theoretical simulation and experimental study. Research results of simulation showed that the polygonal electrode linear ion traps with different structures had different electric field distributions and mass analysis performances. The negative decapole field distorted the performances significantly. The experimental results showed that the mass resolution of reserpine ions (m/z 609) was more than 2500 using a polygonal electrode ion trap. At the same time, mass selective excit...
Source: Chinese Journal of Analytical Chemistry - December 8, 2018 Category: Chemistry Source Type: research
Research on Dispersive Detection Technology Based on Digital Micromirror Device by Atomic Fluorescence Spectrometry
Publication date: December 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 12Author(s): Chen TAO, Chun-Sheng LI, Hong-Xia WANG, Ya-Ru ZHANG, Cheng-Wei ZHAO, Zhi-Heng ZHOU, Zhen-Yu MA, Di TIANAbstractA ultraviolet (UV) digital micromirror spectrometer using a digital micromirror device (DMD) as a spatial light modulator, a grating as a spectroscope and a photomultiplier tube (PMT) as a detector, was specially designed for dispersive hydride generation atomic fluorescence spectrometry (HG-AFS). To improve the detection ability of the UV digital micromirror spectrometer for weak fluorescence signals at 1...
Source: Chinese Journal of Analytical Chemistry - December 8, 2018 Category: Chemistry Source Type: research
Online Capillary Electrophoresis Reaction for Interaction Study of Amino Acid Modified Peptide Nucleic Acid and Proteins
Publication date: December 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 12Author(s): Xiao-Qian WANG, Murtaza Ghulam, Chao ZHU, Feng QUAbstractPeptide nucleic acid (PNA) is a nucleic acid analog which consists of purines, pyrimidines bases, and a neutrally charged peptide backbone. The PNA has the potential as a very useful biological probe for protein analysis since it has more in vivo biological stability as compared to DNA- or RNA-based aptamers. Usually, the addition of amino acids or peptide to the PNA backbone is used to improve its water-solubility and cell-permeability, but these modificatio...
Source: Chinese Journal of Analytical Chemistry - December 8, 2018 Category: Chemistry Source Type: research
Preparation and Characterization of PEGylated Thiophilic Nanoparticles for Rapid Antibody Separation
Publication date: December 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 12Author(s): Fang CHENG, Qian-Cheng FENG, Wei HE, Xian-Ming ZHAO, Qing WANGAbstractMagnetic nanoparticles with novel core-shell structure were prepared for immunoglobulin (IgG) separation, in which thiophilic property of sulfone groups and protein resistance of poly(ethylene glycol) (PEG) moieties were integrated. The step-wise surface reactions on the nanoparticles were characterized by 1H nuclear magnetic resonance (NMR) and surface zeta potential measurements. With human IgG and bovine serum albumin (BSA) as model proteins, ...
Source: Chinese Journal of Analytical Chemistry - December 8, 2018 Category: Chemistry Source Type: research
Influence of Buckminsterfullerene Doping on Properties of Phosphorescent Homojunction Organic Light-Emitting Device
Publication date: December 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 12Author(s): Meng ZHOU, Zheng-Ming MU, Yu ZHENG, Cheng-Ming WANG, Tian-Yu ZHANGAbstractBy p-doping buckminsterfullerene (C60) into a bipolar host 2,7-bis(diphenylphos-phorryl)-9-[4-(N,N-dipheny-lamino)phenyl]-9-phenylfluorene, the device efficiency of the phosphorescent homojunction organic light-emitting device (HJOLED) was pronouncedly enhanced. A two-fold enhancement in luminous efficacy compared with nondoped or MoO3 doped HJOLEDs was observed by employing C60 as the p-dopant. The influence of C60 doping on the device perfo...
Source: Chinese Journal of Analytical Chemistry - December 8, 2018 Category: Chemistry Source Type: research
Progress of Cell Membrane Chromatography and Its Application in Screening Active Ingredients of Traditional Chinese Medicine
Publication date: November 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 11Author(s): Xiao-Yu WANG, Xiao-Fei CHEN, Yan-Qiu GU, Yan CAO, Yong-Fang YUAN, Zhan-Ying HONG, Yi-Feng CHAIAbstractCell membrane chromatography, which has been used to build an in vitro screening model, has become a practical method to screen active ingredients of traditional Chinese medicine (TCM) or study the interaction between drugs and receptors. In this paper, the development of cell membrane chromatography and its preparation methods, the optimization of the system and methodological for stability and other issues were r...
Source: Chinese Journal of Analytical Chemistry - November 14, 2018 Category: Chemistry Source Type: research
Advances in Ambient Ionization for Mass Spectrometry
Publication date: November 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 11Author(s): Xing-Lei ZHANG, Hua ZHANG, Xin-Chen WANG, Ke-Ke HUANG, Dan WANG, Huan-Wen CHENAbstractOver the past decade, ambient mass spectrometry (AMS) has become an important scientific research tool which has been widely used in various important fields such as pharmaceuticals, food, environment, public safety, clinic diagnosis and so on. Ambient ionization technology, as the key for AMS analysis, allows the direct sampling/ionization of analytes from raw practical samples without any sample pretreatment, and has greatly imp...
Source: Chinese Journal of Analytical Chemistry - November 14, 2018 Category: Chemistry Source Type: research
Lipidomics Studies on Mitochondrial Damage of Saccharomyces cerevisiae Induced by Heavy Ion Beam Radiation
Publication date: November 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 11Author(s): Miao-Miao ZHANG, Xiao-Peng GUO, Rui-Yuan LIU, Liang MA, Yue GAO, Dong LU, Wen-Jian LIAbstractUltra high performance liquid chromatography-electrospray ionization-mass spectrometry (UHPLC-ESI-MS) technique combined with multivariate and univariate data analysis methods was used to analyze lipid metabolomics of mitochondria-damaged Saccharomyces cerevisiae (ResD-4) after heavy ion beam radiation. The composition of lipid metabolites in Control and ResD-4 was detected, and a total of 648 kinds of lipid molecules were ...
Source: Chinese Journal of Analytical Chemistry - November 14, 2018 Category: Chemistry Source Type: research
A Cimaterol Molecularly Imprinted Sensor Based on DNA-assisted Recognition
Publication date: November 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 11Author(s): Lian-Ming ZHANG, Dong-You ZHANG, Ying ZENG, Jian-Ping LIAbstractA novel strategy based on DNA induced conformation change was developed by rendering the imprinting cavity with refined structure in order to further improve the selectivity of molecular imprinting membrane. The double-stranded DNA (dsDNA) were first self-assembled on the surface of the gold electrode, then cimaterol (CIM) molecule, taken as the representative target, would bind with the groove of dsDNA to form complex template, together with which the...
Source: Chinese Journal of Analytical Chemistry - November 14, 2018 Category: Chemistry Source Type: research
Detection of Newly Synthesized Proteins via Metabolic Incorporation of Non-natural Amino Acid
This study provided a method for the detection of a specific newly synthesized protein, and characterization of specific protein turnover.Graphical abstractThe TNF-α produced by LPS stimulating cells was labeled with biotin tags via metabolic incorporation of non-natural amino acid and click chemistry which was then specifically captured by the antibody adsorbed on the solid support and detected. (Source: Chinese Journal of Analytical Chemistry)
Source: Chinese Journal of Analytical Chemistry - November 14, 2018 Category: Chemistry Source Type: research
Progress in Research and Application of Micro-Laser-Induced Breakdown Spectroscopy
Publication date: October 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 10Author(s): Lan-Xiang SUN, Wei WANG, Xue-Yong TIAN, Peng ZHANG, Li-Feng QI, Li-Ming ZHENGAbstractThe technique of micro-laser-induced breakdown spectroscopy (μLIBS) usually refers to analyzing the surface of the sample using a compact focused laser beam in the optical microscope range. Compared to conventional laser-induced breakdown spectroscopy (LIBS), it can provide more abundant form, structure, and content information on a smaller, less sample condition. Hence, the application field is very wide. In this paper, the basic ...
Source: Chinese Journal of Analytical Chemistry - October 17, 2018 Category: Chemistry Source Type: research
Applications of High-Resolution Mass Spectrometry in Studies of Brown Carbon
Publication date: October 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 10Author(s): Hong-Xing JIANG, Jun LI, Jiao TANG, Yang-Zhi MO, Gan ZHANGAbstractBrown carbon is a hotspot in the field of atmospheric carbonaceous aerosol research. It has significant influence on regional radiative forcing and exerts climatic effects due to its apparent absorbance in the near ultraviolet-visible region. Brown carbon is mainly derived from incomplete combustion of biomass or coal, as well as secondary sources, such as a series of atmospheric photochemical reactions from volatile organic compounds. Although the co...
Source: Chinese Journal of Analytical Chemistry - October 17, 2018 Category: Chemistry Source Type: research
Facile Synthesis of PEGylated Tungsten-based Nanoprobes for Gastric Computed Tomography Imaging
Publication date: October 2018Source: Chinese Journal of Analytical Chemistry, Volume 46, Issue 10Author(s): Tian-Qi ZHANG, Xue-Li HAN, Yang-Yang HE, Xiao-Jing HE, Jian-Qiu WANG, Qing-Hai YUAN, Jian-Hua LIUAbstractWith the development of science and technology, PEGylated nanoprobes have attracted a great deal of interest in the molecular imaging area of modern medicine. These nanoprobes play an important role especially in diagnosis of gastric diseases. The transition metal oxides as gastric contrast agents based on PEGylated WO3−x nanoprobes were designed in this work. The nanoprobes were developed via a high-temperatur...
Source: Chinese Journal of Analytical Chemistry - October 17, 2018 Category: Chemistry Source Type: research
