Fine ‐needle aspiration of soft tissue perineurioma: A comparative analysis of cytomorphology and immunohistochemistry with benign and malignant mimics
CONCLUSIONSSTP, intramuscular/cellular myxoma, and LGFMS have significant cytomorphologic overlap. Immunohistochemical staining with EMA is not beneficial due to a lack of specificity. Negative MUC4 staining reliably excludes LGFMS. Therefore, a clinically meaningful approach to the FNA biopsy evaluation of a low‐grade myxoid spindle cell neoplasm is to provide a differential diagnosis and to exclude a low‐grade sarcoma. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 8, 2016 Category: Pathology Authors: Eric J. Yang, Jason L. Hornick, Xiaohua Qian Tags: Original Article Source Type: research
Morphologists overestimate the nuclear‐to‐cytoplasmic ratio
CONCLUSIONSMorphologists tended to overestimate the N:C ratio, particularly at ratios close to TPS‐recommended cutoff values. Additional training regarding N:C ratio estimation may help pathologists to adapt to this new system. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 8, 2016 Category: Pathology Authors: Mingjuan L. Zhang, Alan X. Guo, Christopher J. VandenBussche Tags: Original Article Source Type: research
Prognostic impact of a 3 ‐MicroRNA signature in cytological samples of small cell lung cancer
CONCLUSIONSA specific 3‐miRNA signature is potentially useful for predicting survival for patients with SCLC, and it may be feasible with cytological samples taken during standard diagnostic procedures. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 5, 2016 Category: Pathology Authors: Giuseppe Mancuso, Enrica Bovio, Ottavio Rena, Eltjona Rrapaj, Francesca Mercalli, Claudia Veggiani, Alessia Paganotti, Silvano Andorno, Renzo Boldorini Tags: Original Article Source Type: research
Prognostic impact of a 3‐MicroRNA signature in cytological samples of small cell lung cancer
CONCLUSIONSA specific 3‐miRNA signature is potentially useful for predicting survival for patients with SCLC, and it may be feasible with cytological samples taken during standard diagnostic procedures. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 5, 2016 Category: Pathology Authors: Giuseppe Mancuso, Enrica Bovio, Ottavio Rena, Eltjona Rrapaj, Francesca Mercalli, Claudia Veggiani, Alessia Paganotti, Silvano Andorno, Renzo Boldorini Tags: Original Article Source Type: research
Clinical mutational profiling of bone metastases of lung and colon carcinoma and malignant melanoma using next‐generation sequencing
CONCLUSIONSNext‐generation sequencing assays demonstrated clinical utility in metastatic bone specimens. FNA (smear and cell block) and core‐biopsy specimens provided adequate resources of nucleic acids for molecular profiling of metastatic bone lesions. The current findings suggest the need for developing specific tissue procurement and processing protocols for bone metastases and greater use of small biopsy and FNA specimens. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 30, 2016 Category: Pathology Authors: Gang Zheng, Ming‐Tseh Lin, Parvez M. Lokhandwala, Katie Beierl, George J. Netto, Christopher D. Gocke, James R. Eshleman, Edward McCarthy, Peter B. Illei Tags: Original Article Source Type: research
Analytical validity of a microRNA‐based assay for diagnosing indeterminate thyroid FNA smears from routinely prepared cytology slides
CONCLUSIONSThe microRNA‐based assay was robust to various physical processing conditions and to differing sample characteristics. Given the assay's performance, robustness, and use of routinely prepared FNA slides, it has the potential to provide valuable aid for physicians in the diagnosis of thyroid nodules. Cancer Cytopathol 2016;000:000‐000. © 2016 Rosetta Genomics. Cancer Cytopathology published by Wiley Periodicals, Inc. on behalf of American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 30, 2016 Category: Pathology Authors: Hila Benjamin, Temima Schnitzer‐Perlman, Alexander Shtabsky, Christopher J. VandenBussche, Syed Z. Ali, Zdenek Kolar, Fabio Pagni, , Dganit Bar, Eti Meiri Tags: Original Article Source Type: research
Noninvasive follicular thyroid neoplasm with papillary‐like nuclear features (NIFTP): A changing paradigm in thyroid surgical pathology and implications for thyroid cytopathology
The change in the diagnosis of noninvasive encapsulated follicular variant papillary thyroid carcinoma to noninvasive follicular thyroid neoplasm with papillary‐like nuclear features (ie, not carcinoma) will have significant impact on the risk of malignancy for categories according to The Bethesda System for Reporting Thyroid Cytopathology, and especially for the indeterminate categories. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 30, 2016 Category: Pathology Authors: Zubair W. Baloch, Raja R. Seethala, William C. Faquin, Mauro G. Papotti, Fulvio Basolo, Guido Fadda, Gregory W. Randolph, Steven P. Hodak, Yuri E. Nikiforov, Susan J. Mandel Tags: Commentary Source Type: research
HPV vaccination in Southern Africa: A jab of hope in the fight against cervical cancer
Cervical cancer is one of the most common causes of cancer‐related deaths in Southern Africa. Human papillomavirus vaccination offers a chance to markedly reduce this burden of disease, although challenges with vaccine delivery need to be overcome. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 30, 2016 Category: Pathology Authors: Pamela Michelow, Cynthia Firnhaber Tags: Commentary Source Type: research
Nuclear grade based on transbronchial cytology is an independent prognostic factor in patients with advanced, unresectable non‐small cell lung cancer
CONCLUSIONSNuclear grade based on nuclear diameter was found to be independently associated with prognosis in patients with advanced, unresectable NSCLC. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 30, 2016 Category: Pathology Authors: Kyuichi Kadota, Yumi Miyai, Naomi Katsuki, Yoshio Kushida, Toru Matsunaga, Masaya Okuda, Hiroyasu Yokomise, Nobuhiro Kanaji, Shuji Bandoh, Reiji Haba Tags: Original Article Source Type: research
A superior method for cell block preparation for fine ‐needle aspiration biopsies
CONCLUSIONSColB appears to be a superior technique for CB, yielding greater cellularity, preservation, and architecture in the majority of cases. Cancer Cytopathol 2016;124:508–18. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 21, 2016 Category: Pathology Authors: Ronald Balassanian, Geoffrey D. Wool, Jill C. Ono, Jolanta Olejnik ‐Nave, Molinda M. Mah, Brenda J. Sweeney, Hava Liberman, Britt‐Marie Ljung, Martha B. Pitman Tags: Original Article Source Type: research
Rise of the predators: Business is booming in the murky global market of suspect and sham publishers and journals
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 13, 2016 Category: Pathology Authors: Bryn Nelson Tags: CytoSource Source Type: research
2016 publication schedule
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 13, 2016 Category: Pathology Tags: Issue Information Source Type: research
Issue Information
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 13, 2016 Category: Pathology Tags: Issue Information Source Type: research
High apoptotic index in urine cytology is associated with high ‐grade urothelial carcinoma
CONCLUSIONSExcluding ileal conduit urine specimens, the finding of a high apoptotic index (score ≥ 2) with the presence of pyknosis or karyorrhexis in ≥10 per 10 high‐power fields in the urine cytology appears to be significantly associated with HGUC (P<.05). Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 11, 2016 Category: Pathology Authors: Chi ‐Shun Yang, Shaoxiong Chen, Harvey M. Cramer, Howard H. Wu Tags: Original Article Source Type: research
High apoptotic index in urine cytology is associated with high ‐grade urothelial carcinoma
In this issue, Yang and colleagues report that, using a high apoptotic index as a feature, the 2 categories “high‐grade urine cytology” (HGUC) and “atypical urothelial cells, cannot exclude HGUC,” yield almost equal numbers of samples that, when combined, result in a tissue diagnosis of HGUC 79% of the time. The authors conclude that adding a high apoptotic index to the traditional cytologic features of urothelial carcinoma can improve the sensitivity of urinary cytology for detecting HGUC. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - April 11, 2016 Category: Pathology Authors: Dorothy L. Rosenthal Tags: Editorial Source Type: research
