High apoptotic index in urine cytology is associated with high ‐grade urothelial carcinoma

In this issue, Yang and colleagues report that, using a high apoptotic index as a feature, the 2 categories “high‐grade urine cytology” (HGUC) and “atypical urothelial cells, cannot exclude HGUC,” yield almost equal numbers of samples that, when combined, result in a tissue diagnosis of HGUC 79% of the time. The authors conclude that adding a high apoptotic index to the traditional cytologic features of urothelial carcinoma can improve the sensitivity of urinary cytology for detecting HGUC.
Source: Cancer Cytopathology - Category: Pathology Authors: Tags: Editorial Source Type: research