Reverse transcription–polymerase chain reaction molecular testing of cytology specimens: Pre‐analytic and analytic factors
The introduction of molecular testing into cytopathology laboratory practice has expanded the types of samples considered feasible for identifying genetic alterations that play an essential role in cancer diagnosis and treatment. Reverse transcription–polymerase chain reaction (RT‐PCR), a sensitive and specific technical approach for amplifying a defined segment of RNA after it has been reverse‐transcribed into its DNA complement, is commonly used in clinical practice for the identification of recurrent or tumor‐specific fusion gene events. Real‐time RT‐PCR (quantitative RT‐PCR), a technical variation, also p...
Source: Cancer Cytopathology - June 30, 2016 Category: Pathology Authors: Julia A. Bridge Tags: Review Article Source Type: research
Variations in cancer centers ’ use of cytology for the diagnosis of unresectable pancreatic cancer in the National Cancer Data Base
CONCLUSIONSGreater than 25% of unresectable pancreatic cancers were diagnosed definitively with cytology, with wide variation in its use by facility type, suggesting opportunities for quality improvement interventions that increase the use of cytology. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 26, 2016 Category: Pathology Authors: Ted Gansler, Stacey A. Fedewa, Chun Chieh Lin, Ahmedin Jemal, Elizabeth M. Ward Tags: Original Article Source Type: research
Variations in cancer centers’ use of cytology for the diagnosis of unresectable pancreatic cancer in the National Cancer Data Base
CONCLUSIONSGreater than 25% of unresectable pancreatic cancers were diagnosed definitively with cytology, with wide variation in its use by facility type, suggesting opportunities for quality improvement interventions that increase the use of cytology. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 26, 2016 Category: Pathology Authors: Ted Gansler, Stacey A. Fedewa, Chun Chieh Lin, Ahmedin Jemal, Elizabeth M. Ward Tags: Original Article Source Type: research
Reply to HPV test results provide useful risk stratification information in women with ASC ‐H Pap test findings
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 22, 2016 Category: Pathology Authors: Marc Arbyn, Lan Xu, Nicolas Wentzensen Tags: Correspondence Source Type: research
HPV test results provide useful risk stratification information in women with ASC ‐H Pap test findings
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 22, 2016 Category: Pathology Authors: R. Marshall Austin, Chengquan Zhao Tags: Correspondence Source Type: research
Reply to HPV test results provide useful risk stratification information in women with ASC‐H Pap test findings
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 22, 2016 Category: Pathology Authors: Marc Arbyn, Lan Xu, Nicolas Wentzensen Tags: Correspondence Source Type: research
Impact of specific patterns on the sensitivity for follicular and Hurthle cell carcinoma in thyroid fine‐needle aspiration
CONCLUSIONSDiagnosing FNA specimens with microfollicles without atypia as benign appears to significantly reduce the sensitivity for follicular carcinoma to 75%; in contrast, diagnosing FNA specimens with Hurthle cells in flat sheets without anisonucleosis as benign does not. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 19, 2016 Category: Pathology Authors: Andrew A. Renshaw, Edwin W. Gould Tags: Original Article Source Type: research
Use of cytology as an auxiliary diagnostic tool in autopsies
CONCLUSIONSCytology showed a good correlation with histology, particularly for neoplastic cases and specimens with minimal pathological alterations, and could be used as an alternative diagnostic method in partial or restricted postmortem examinations. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 19, 2016 Category: Pathology Authors: Luana Andrade, Vitória Lana Massarente, Stéphanie Corradini Tormin, Karina Braga Ribeiro, Geanete Pozzan, Mauro Ajaj Saieg Tags: Original Article Source Type: research
Two decades of lung cancer through the pages of Cancer Cytopathology
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 12, 2016 Category: Pathology Authors: Gladwyn Leiman Tags: Editorial Source Type: research
Gladwyn Leiman: An appreciation
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 12, 2016 Category: Pathology Authors: Celeste N. Powers Tags: Editorial Source Type: research
Caging the pack
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 12, 2016 Category: Pathology Authors: Bryn Nelson Tags: CytoSource Source Type: research
2016 publication schedule
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 12, 2016 Category: Pathology Tags: Issue Information Source Type: research
Issue Information
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 12, 2016 Category: Pathology Tags: Issue Information Source Type: research
Validation study of HPV DNA detection from stained FNA smears by polymerase chain reaction: Improving the diagnostic workup of patients with a tumor on the neck
CONCLUSIONSThe detection of HPV DNA in MGG‐stained FNA smears by PCR is a valid method that could be implemented in routine clinical practice. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 31, 2016 Category: Pathology Authors: Hani Ibrahim Channir, Christian Grønhøj Larsen, Lise Barlebo Ahlborn, Thomas van Overeem Hansen, Thomas Alexander Gerds, Birgitte Wittenborg Charabi, Ben Vainer, Christian von Buchwald, Christel Bræmer Lajer, Katalin Kiss Tags: Original Article Source Type: research
Cytopathologic features of NUT midline carcinoma: A series of 26 specimens from 13 patients
CONCLUSIONSNMC is a recently recognized tumor that should be considered in the differential diagnosis of small round cell tumors, especially but not exclusively in the mediastinum and the head and neck. The cytologic features of NMC overlap considerably with those of other neoplasms, and a definitive diagnosis depends on a demonstration of NUT translocation by either immunohistochemical or molecular means. Cancer Cytopathol 2016. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - May 31, 2016 Category: Pathology Authors: Justin A. Bishop, Christopher A. French, Syed Z. Ali Tags: Original Article Source Type: research
