Next ‐generation sequencing of urine specimens: A novel platform for genomic analysis in patients with non–muscle‐invasive urothelial carcinoma treated with bacille Calmette‐Guérin
CONCLUSIONSUrine specimens can replace tissue as a substrate for NGS analysis of HR NMIUC. Several genomic alterations identified in urine specimens might be associated with histological features and clinical characteristics. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - March 1, 2017 Category: Pathology Authors: Sasinya N. Scott, Irina Ostrovnaya, Caroline M. Lin, Nancy Bouvier, Bernard H. Bochner, Gopakumar Iyer, David Solit, Michael F. Berger, Oscar Lin Tags: Original Article Source Type: research

Percutaneous biopsy of the renal mass: FNA or core needle biopsy?
CONCLUSIONSIn the current study, both FNA and CB demonstrated excellent diagnostic accuracy (96% and 94%, respectively). The combination of FNA and CB was found to significantly improve the diagnostic rate when compared with either FNA alone (92% vs 72%; P<.05) or CB alone (92% vs 87%). Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - March 1, 2017 Category: Pathology Authors: Chi ‐Shun Yang, Euna Choi, Muhammad T. Idrees, Shaoxiong Chen, Howard H. Wu Tags: Original Article Source Type: research

Brian T. Collins, MD
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - March 1, 2017 Category: Pathology Authors: Daniel F. I. Kurtycz, Kristen A. Atkins Tags: In Memoriam Source Type: research

Bridging the Gap: Training and Education in the Pathology and Cytopathology Sphere
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - February 28, 2017 Category: Pathology Authors: Diane Davis Davey Tags: Bridging the Gap Source Type: research

The squamous situation: Ancillary testing in pulmonary squamous cell carcinoma and implications for cytology laboratories
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - February 26, 2017 Category: Pathology Authors: Sara E. Monaco Tags: Molecular Minute Source Type: research

External quality assurance in nongynecologic cytology: The Australasian experience
CONCLUSIONSThe use of multiple preparations of the same specimen has allowed interlaboratory comparison, and the quality assurance program has played an educational role as well as informing the laboratory accreditation process. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - February 26, 2017 Category: Pathology Authors: Paul W. Shield, Felicity Frost, Jo L. Finnimore, R. Gordon Wright, Margaret C. Cummings Tags: Original Article Source Type: research

Young Investigator Challenge: Building an ultrasound ‐guided FNA clinic—our 5‐year experience: From project to practice
CONCLUSIONSFNAs performed by cytopathologists have a high‐rate of ROSE/adequacy and a low diagnostic discrepancy rate. Cytopathologists as interventionalists provide optimal care and excellent patient satisfaction. Cancer Cytopathol 2017;125:161–168. © 2016 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - February 23, 2017 Category: Pathology Authors: Oana C. Rafael, Melissa Klein, Melissa M. Serbonich, Bhumika Vadalia, Kasturi Das, Cecilia E. Gimenez Tags: Original Article Source Type: research

Every step you take?
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - February 15, 2017 Category: Pathology Authors: Bryn Nelson Tags: CytoSource Source Type: research

Issue Information
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - February 15, 2017 Category: Pathology Tags: Issue Information Source Type: research

Thyroid cytology —nuclear versus architectural atypia within the “Atypia of undetermined significance/follicular lesion of undetermined significance” Bethesda category have significantly different rates of malignancy
CONCLUSIONSThe disparity between malignancy risks within the Bethesda “atypical” category suggests that cytologic (nuclear) atypia is significantly more predictive of malignancy than architectural atypia. This supports the substratification of patients according to risk and a corresponding management approach within this category. A sonographic finding of irregular margins is also predictive for malignancy. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - February 12, 2017 Category: Pathology Authors: Tiffany Rui Xuan Gan, Min En Nga, Jeffrey Huey Yew Lum, Wendy Meihua Wong, Wee Boon Tan, Rajeev Parameswaran, Kee Yuan Ngiam Tags: Original Article Source Type: research

Young Investigator Challenge: Molecular testing in noninvasive follicular thyroid neoplasm with papillary ‐like nuclear features
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - February 6, 2017 Category: Pathology Authors: N. Paul Ohori, Raja R. Seethala, Yuri E. Nikiforov Tags: Correspondence Source Type: research

Qualifiers of atypia in the cytologic diagnosis of thyroid nodules are associated with different Afirma gene expression classifier results and clinical outcomes
CONCLUSIONSThe performance characteristics of Afirma GEC testing vary, depending on qualifiers of cytologic atypia. Recognition of these differences may enable clinicians to provide improved counseling and treatment recommendations to patients. Cancer Cytopathol 2016. © 2017 The Authors. Cancer Cytopathology published by Wiley Periodicals, Inc. on behalf of American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - February 1, 2017 Category: Pathology Authors: Sylvan C. Baca, Kristine S. Wong, Kyle C. Strickland, Howard T. Heller, Matthew I. Kim, Justine A. Barletta, Edmund S. Cibas, Jeffrey F. Krane, Ellen Marqusee, Trevor E. Angell Tags: Original Article Source Type: research

Can noninvasive follicular thyroid neoplasm with papillary ‐like nuclear features be distinguished from classic papillary thyroid carcinoma and follicular adenomas by fine‐needle aspiration?
CONCLUSIONSSeveral statistically significant associations appear to be present between cytomorphologic features and surgical diagnosis that may be used as clues to distinguish NIFTP, PTC, and FA on fine‐needle aspiration. Although diagnostic confirmation of NIFTP must occur at the time of excision, similar to follicular neoplasms, the possibility of NIFTP may be raised preoperatively on cytology. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - January 31, 2017 Category: Pathology Authors: Tamar C. Brandler, Fang Zhou, Cheng Z. Liu, Margaret Cho, Ryan P. Lau, Aylin Simsir, Kepal N. Patel, Wei Sun Tags: Original Article Source Type: research

Improved risk stratification for patients with high ‐grade urothelial carcinoma following application of the Paris System for Reporting Urinary Cytology
CONCLUSIONSWhen applied to malignant UTC specimens, TPS criteria improved specimen risk stratification by upgrading approximately 40% of indeterminate specimens into higher risk categories while not significantly changing the frequency of HGUC diagnoses. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - January 31, 2017 Category: Pathology Authors: Morgan L. Cowan, Dorothy L. Rosenthal, Christopher J. VandenBussche Tags: Original Article Source Type: research

Cytologic characteristics of circulating epithelioid cells in pancreatic disease
CONCLUSIONSCECs were observed in patients with malignant and nonmalignant pancreatic disease, but not in healthy controls. There were no morphologic differences observed between cells from different pancreatic diseases, suggesting that numerous conditions may be associated with CECs in the circulation and that care must be taken not to overinterpret cells identified by cytomorphology as indicative of circulating tumor cells of pancreatic cancer. Additional studies are required to determine the origin and clinical significance of these cells. Cancer (Cancer Cytopathol) 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - January 31, 2017 Category: Pathology Authors: Matthew W. Rosenbaum, Christy E. Cauley, Birte Kulemann, Andrew S. Liss, Carlos Fernandez ‐del Castillo, Andrew L. Warshaw, Keith D. Lillemoe, Sarah P. Thayer, Martha B. Pitman Tags: Original Article Source Type: research