Three ‐year cytohistological correlation of salivary gland FNA cytology at a tertiary center with the application of the Milan system for risk stratification
CONCLUSIONSSalivary gland FNA continues to have high diagnostic accuracy and is thus helpful for guiding management. Neoplasms with classic cytomorphology are easily diagnosed; however, in difficult cases showing overlapping features, the use of the Milan system could be beneficial. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - July 1, 2017 Category: Pathology Authors: Manish Rohilla, Priya Singh, Arvind Rajwanshi, Nalini Gupta, Radhika Srinivasan, Pranab Dey, Rakesh K. Vashishta Tags: Original Article Source Type: research
Adequate sampling of multiple thyroid nodules by fine ‐needle aspiration
CONCLUSIONSBiopsy of 3 different nodules in patients with multiple nodules appears to lower the risk of malignancy to that of a benign fine‐needle aspiration specimen. Although exceptions can occur, cytologists may be able to improve the accuracy of their diagnoses by focusing predominantly on identifying papillary carcinoma after the first 2 nodules have been biopsied. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - July 1, 2017 Category: Pathology Authors: Andrew A. Renshaw, Ewing W. Gould Tags: Original Article Source Type: research
ALK and ROS1 testing on lung cancer cytologic samples: Perspectives
Cytologic sampling is the mainstay of diagnosing advanced lung cancer. Moreover, to select patients for personalized first‐line or second‐line treatment, epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) and c‐ros oncogene 1 (ROS1) rearrangements are tested on cytologic preparations. Commercially available fluorescence in situ hybridization (FISH) and immunocytochemistry (ICC) assays have primarily been used for the identification of cells harboring ALK or ROS1 gene fusions on histologic rather than cytologic preparations. However, it is now recognized that FISH and ICC also can b...
Source: Cancer Cytopathology - July 1, 2017 Category: Pathology Authors: Pasquale Pisapia, Maria D. Lozano, Elena Vigliar, Claudio Bellevicine, Francesco Pepe, Umberto Malapelle, Giancarlo Troncone Tags: Review Article Source Type: research
Next ‐generation sequencing of cytologic preparations: An analysis of quality metrics
CONCLUSIONSThe adequacy rate of cytology smears/LBPs for NGS is comparable to that of core BXs or CBs. Increased values for the mean insert size, mean target coverage, and percent usable bases, along with a lower duplication rate, suggest that smears/LBPs provide higher quality DNA than formalin‐fixed material. Cytology smears/LBPs can serve as a valuable source of material for molecular testing. Cancer (Cancer Cytopathol) 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - July 1, 2017 Category: Pathology Authors: David H. Hwang, Elizabeth P. Garcia, Matthew D. Ducar, Edmund S. Cibas, Lynette M. Sholl Tags: Original Article Source Type: research
Erratum: Ordi J, Sagasta A, Munmany M, Rodr íguez‐Carunchio L, Torné A and del Pino M. Usefulness of p16/Ki67 immunostaining in the triage of women referred to colposcopy. Cancer Cytopathology. 2014;122:227‐35.
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - July 1, 2017 Category: Pathology Tags: Erratum Source Type: research
The Milan System for Reporting Salivary Gland Cytopathology: Analysis and suggestions of initial survey
CONCLUSIONSResults of the survey demonstrated strong support for the development of a unified system for reporting SGC. Cancer Cytopathol 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - July 1, 2017 Category: Pathology Authors: Esther Diana Rossi, William C. Faquin, Zubair Baloch, G üliz A. Barkan, Maria Pia Foschini, Marc Pusztaszeri, Philippe Vielh, Daniel F. I. Kurtycz Tags: Original Article Source Type: research
Why is digital pathology in cytopathology lagging behind surgical pathology?
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 28, 2017 Category: Pathology Authors: Simone L. Van Es Tags: Correspondence Source Type: research
Programmed death ‐ligand 1 testing in patients with non–small cell lung cancer: Ready for prime time?
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 16, 2017 Category: Pathology Authors: Justin F. Gainor Tags: Clinician's Corner Source Type: research
A value proposition: In the quest to minimize low ‐value cancer care, the effort to raise quality and lower costs remains a work in progress
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 13, 2017 Category: Pathology Authors: Bryn Nelson Tags: CytoSource Source Type: research
Issue Information
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 13, 2017 Category: Pathology Tags: Issue Information Source Type: research
Digital image analysis supports a nuclear ‐to‐cytoplasmic ratio cutoff value of 0.5 for atypical urothelial cells
CONCLUSIONSThe identification of AUC with an N:C ratio >0.486 has a high predictive power for HGUC on follow‐up in AUC specimens. This justifies using the N:C ratio as a required criterion for the AUC category. Individual laboratories using different cytopreparation methods may require independent validation of the N:C ratio cutoff value. Cancer (Cancer Cytopathol) 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 5, 2017 Category: Pathology Authors: Jen ‐Fan Hang, Vivek Charu, M. Lisa Zhang, Christopher J. VandenBussche Tags: Original Article Source Type: research
Critical diagnoses in cytopathology: Experience at a large medical center
CONCLUSIONSUse of a code for critical cytopathology diagnoses was found to be occurring increasingly at the study health care system. Pathologists at the academic and community hospitals in the study institution used this code somewhat differently, reflecting the need to satisfy communication with clinicians in different practice settings. Nevertheless, the authors' experiences with using a code for critical diagnoses not only ensured timely patient care but also proposed a model that could be used by other medical specialties to enhance communication and improve quality of care. Cancer Cytopathol 2017. © 2017 American Ca...
Source: Cancer Cytopathology - June 1, 2017 Category: Pathology Authors: Juan Xing, Lindsey Seigh, Sara E. Monaco, N. Paul Ohori, Samuel A. Yousem, Rajnikant Amin, Liron Pantanowitz Tags: Original Article Source Type: research
The influence of the noninvasive follicular thyroid neoplasm with papillary ‐like nuclear features (NIFTP) resection diagnosis on the false‐positive thyroid cytology rate relates to quality assurance thresholds and the application of NIFTP criteria
CONCLUSIONSIn the current large series, NIFTP reclassification did not appear to significantly alter the high ROM for the PFM diagnosis. The authors attribute this finding to a strict quality assurance policy, an emphasis on key cytologic criteria, and systematic application of the NIFTP criteria to follicular‐patterned lesions. Cancer (Cancer Cytopathol) 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 1, 2017 Category: Pathology Authors: N. Paul Ohori, Jenna Wolfe, Sally E. Carty, Linwah Yip, Shane O. LeBeau, Aaron N. Berg, Karen E. Schoedel, Yuri E. Nikiforov, Raja R. Seethala Tags: Original Article Source Type: research
Reply to Why is digital pathology in cytopathology lagging behind surgical pathology?
(Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 1, 2017 Category: Pathology Authors: Matthew G. Hanna, Liron Pantanowitz Tags: Correspondence Source Type: research
Distinguishing parathyroid and thyroid lesions on ultrasound ‐guided fine‐needle aspiration: A correlation of clinical data, ancillary studies, and molecular analysis
CONCLUSIONSLesions with follicular lesion of undetermined significance‐like or oncocytic features are prone to misdiagnosis. The current study identified distinct cytologic patterns in parathyroid lesions suggestive of parathyroid origin, which, together with PTH immunostains or assay, molecular studies, or sestamibi scans, aid in distinguishing parathyroid from thyroid lesions. Cancer (Cancer Cytopathol) 2017. © 2017 American Cancer Society. (Source: Cancer Cytopathology)
Source: Cancer Cytopathology - June 1, 2017 Category: Pathology Authors: Margaret Cho, Thaira Oweity, Tamar C. Brandler, Karen Fried, Pascale Levine Tags: Original Article Source Type: research
