Digital image analysis supports a nuclear ‐to‐cytoplasmic ratio cutoff value of 0.5 for atypical urothelial cells

CONCLUSIONSThe identification of AUC with an N:C ratio >0.486 has a high predictive power for HGUC on follow‐up in AUC specimens. This justifies using the N:C ratio as a required criterion for the AUC category. Individual laboratories using different cytopreparation methods may require independent validation of the N:C ratio cutoff value. Cancer (Cancer Cytopathol) 2017. © 2017 American Cancer Society.
Source: Cancer Cytopathology - Category: Pathology Authors: Tags: Original Article Source Type: research