Molecular Modeling for Better Understanding of Cucumovirus Pathology
Publication date: Available online 26 July 2018Source: Advances in Virus ResearchAuthor(s): Katalin Salánki, Ákos Gellért, Katalin Nemes, Zoltán Divéki, Ervin BalázsAbstractCucumber mosaic virus (CMV) is a small RNA virus capable of infecting a wide variety of plant species. The high economic losses due to the CMV infection made this virus a relevant subject of scientific studies, which were further facilitated by the small size of the viral genome. Hence, CMV also became a model organism to investigate the molecular mechanism of pathogenesis. All viral functions are dependent on intra- and intermolecular interaction...
Source: Advances in Virus Research - July 27, 2018 Category: Virology Source Type: research
Integration of Omics Approaches toward Understanding Whitefly Transmission of Viruses
Publication date: Available online 26 July 2018Source: Advances in Virus ResearchAuthor(s): William M. WintermantelAbstractViruses transmitted by whiteflies are predominantly classified as having either persistent circulative or semipersistent transmission, and the majority of studies have addressed transmission of viruses in the genera Begomovirus (family Geminiviridae) and Crinivirus (family Closteroviridae), respectively. Early studies on vector transmission primarily addressed individual aspects of transmission; however, with the breadth of new technology now available, an increasingly greater number of studies involve...
Source: Advances in Virus Research - July 27, 2018 Category: Virology Source Type: research
TMV Particles: The Journey From Fundamental Studies to Bionanotechnology Applications
Publication date: Available online 26 July 2018Source: Advances in Virus ResearchAuthor(s): George P. Lomonossoff, Christina WegeAbstractEver since its initial characterization in the 19th century, tobacco mosaic virus (TMV) has played a prominent role in the development of modern virology and molecular biology. In particular, research on the three-dimensional structure of the virus particles and the mechanism by which these assemble from their constituent protein and RNA components has made TMV a paradigm for our current view of the morphogenesis of self-assembling structures, including viral particles. More recently, thi...
Source: Advances in Virus Research - July 27, 2018 Category: Virology Source Type: research
In Memoriam: The Career, Achievements, and Legacy of Milton Zaitlin
Publication date: Available online 26 July 2018Source: Advances in Virus ResearchAuthor(s): Peter Palukaitis, Marilyn J. Roossinck (Source: Advances in Virus Research)
Source: Advances in Virus Research - July 27, 2018 Category: Virology Source Type: research
Dichorhaviruses in Their Host Plants and Mite Vectors
Publication date: Available online 26 July 2018Source: Advances in Virus ResearchAuthor(s): Ralf G. Dietzgen, Juliana Freitas-Astúa, Camila Chabi-Jesus, Pedro L. Ramos-González, Michael M. Goodin, Hideki Kondo, Aline D. Tassi, Elliot W. KitajimaAbstractA group of related bacilliform, nuclear viruses with a bisegmented negative-sense RNA genome that are transmitted by Brevipalpus mites likely in a circulative–propagative manner were recently classified in the new genus Dichorhavirus, family Rhabdoviridae. These viruses cause localized lesions on leaves, stems, and fruits of economically significant horticultural and orn...
Source: Advances in Virus Research - July 27, 2018 Category: Virology Source Type: research
Tobamoviruses as Models for the Study of Virus Evolution
Publication date: Available online 26 July 2018Source: Advances in Virus ResearchAuthor(s): Aurora Fraile, Fernando García-ArenalAbstractThe study of tobacco mosaic virus and other tobamovirus species has greatly contributed to the development of all areas of virology, including virus evolution. Research with tobamoviruses has been pioneer, or particularly significant, in all major areas of research in this field, including: the characterization of the genetic diversity of virus populations, the mechanisms and rates of generation of genetic diversity, the analysis of the genetic structure of virus populations and of the f...
Source: Advances in Virus Research - July 27, 2018 Category: Virology Source Type: research
Viral Manipulation of Plant Stress Responses and Host Interactions With Insects
Publication date: Available online 25 July 2018Source: Advances in Virus ResearchAuthor(s): John P. Carr, Ruairí Donnelly, Trisna Tungadi, Alex M. Murphy, Sanjie Jiang, Ana Bravo-Cazar, Ju-Yeon Yoon, Nik J. Cunniffe, Beverley J. Glover, Christopher A. GilliganAbstractDo the alterations in plant defensive signaling and metabolism that occur in susceptible hosts following virus infection serve any purpose beyond directly aiding viruses to replicate and spread? Or indeed, are these modifications to host phenotype purely incidental consequences of virus infection? A growing body of data, in particular from studies of viruses ...
Source: Advances in Virus Research - July 26, 2018 Category: Virology Source Type: research
Series Page
Publication date: 2018Source: Advances in Virus Research, Volume 100Author(s): (Source: Advances in Virus Research)
Source: Advances in Virus Research - July 11, 2018 Category: Virology Source Type: research
Contributors
Publication date: 2018Source: Advances in Virus Research, Volume 100Author(s): (Source: Advances in Virus Research)
Source: Advances in Virus Research - July 11, 2018 Category: Virology Source Type: research
Preface to Volume 100: History and Looking Forward
Publication date: 2018Source: Advances in Virus Research, Volume 100Author(s): Thomas C. Mettenleiter, Margaret Kielian, Marilyn J. Roossinck (Source: Advances in Virus Research)
Source: Advances in Virus Research - July 11, 2018 Category: Virology Source Type: research
Chapter One - The Species Problem in Virology
Publication date: 2018Source: Advances in Virus Research, Volume 100Author(s): Marc H.V. Van RegenmortelAbstractVirus classification deals with conceptual species classes that have viruses as their members. A virus species cannot be described but can only be defined by listing certain species-defining properties of its member. However, it is not possible to define a virus species by using a single species-defining property. The new 2013 official definition of virus species is not appropriate because it applies equally to virus genera. A nucleotide motif is a chemical part of a viral genome and is not a species-defining pro...
Source: Advances in Virus Research - July 11, 2018 Category: Virology Source Type: research
Chapter Two - The Role of Immune Responses in HIV Mother-to-Child Transmission
Publication date: 2018Source: Advances in Virus Research, Volume 100Author(s): Caitlin Milligan, Jennifer A. Slyker, Julie OverbaughAbstractHIV mother-to-child transmission (MTCT) represents a success story in the HIV/AIDS field given the significant reduction in number of transmission events with the scale-up of antiretroviral treatment and other prevention methods. Nevertheless, MTCT still occurs and better understanding of the basic biology and immunology of transmission will aid in future prevention and treatment efforts. MTCT is a unique setting given that the transmission pair is known and the infant receives passive...
Source: Advances in Virus Research - July 11, 2018 Category: Virology Source Type: research
Chapter Three - African Swine Fever Virus Biology and Vaccine Approaches
Publication date: 2018Source: Advances in Virus Research, Volume 100Author(s): Yolanda Revilla, Daniel Pérez-Núñez, Juergen A. RichtAbstractAfrican swine fever (ASF) is an acute and often fatal disease affecting domestic pigs and wild boar, with severe economic consequences for affected countries. ASF is endemic in sub-Saharan Africa and the island of Sardinia, Italy. Since 2007, the virus emerged in the republic of Georgia, and since then spread throughout the Caucasus region and Russia. Outbreaks have also been reported in Belarus, Ukraine, Lithuania, Latvia, Estonia, Romania, Moldova, Czech Republic, and Poland, thre...
Source: Advances in Virus Research - July 11, 2018 Category: Virology Source Type: research
Chapter Four - Morbillivirus Pathogenesis and Virus–Host Interactions
Publication date: 2018Source: Advances in Virus Research, Volume 100Author(s): Kristin Pfeffermann, Mareike Dörr, Florian Zirkel, Veronika von MesslingAbstractDespite the availability of safe and effective vaccines against measles and several animal morbilliviruses, they continue to cause regular outbreaks and epidemics in susceptible populations. Morbilliviruses are highly contagious and share a similar pathogenesis in their respective hosts. This review provides an overview of morbillivirus history and the general replication cycle and recapitulates Morbillivirus pathogenesis focusing on common and unique aspects seen i...
Source: Advances in Virus Research - July 11, 2018 Category: Virology Source Type: research
Chapter Five - Viruses of Plant-Interacting Fungi
Publication date: 2018Source: Advances in Virus Research, Volume 100Author(s): Bradley I. Hillman, Aulia Annisa, Nobuhiro SuzukiAbstractPlant-associated fungi are infected by viruses at the incidence rates from a few % to over 90%. Multiple viruses often coinfect fungal hosts, and occasionally alter their phenotypes, but most of the infections are asymptomatic. Phenotypic alterations are grouped into two types: harmful or beneficial to the host fungi. Harmful interactions between viruses and hosts include hypovirulence and/or debilitation that are documented in a number of phytopathogenic fungi, exemplified by the chestnut...
Source: Advances in Virus Research - July 11, 2018 Category: Virology Source Type: research
