Quality of life in substance use disorder patients with and without attention deficit hyperactivity disorder 12  months after treatment: a naturalistic follow-up study
AbstractThere is sparse research on quality of life (QoL) as an outcome measure in patients with substance use disorders (SUD), with or without attention deficit hyperactivity disorder (ADHD). We aimed to investigate whether SUD patients with and without ADHD (SUD  + ADHD vs. SUD − ADHD) differed in QoL at baseline and at a 12-month follow-up after SUD treatment. The groups were additionally compared with data from a national population sample (NPS). From a sample of 16 SUD + ADHD and 87 SUD − ADHD patients originally recruited between 201 0 and 2012, eight SUD + ADHD (50.0%) and 28 SUD − ADHD...
Source: ADHD Attention Deficit and Hyperactivity Disorders - March 21, 2019 Category: Psychiatry Source Type: research

Relational impairments, sluggish cognitive tempo, and severe inattention are associated with elevated self-rated depressive symptoms in adolescents with ADHD
This study examines how ADHD-related symptoms and impairments interact to predict depression symptoms in young adolescents with ADHD. A sample of 342 adolescents (71% male, mean age  = 13 years old) with DSM-IV-TR diagnosed ADHD completed baseline clinical assessments upon entry to a psychosocial treatment study for ADHD. Ratings of ADHD and sluggish cognitive tempo (SCT) symptoms, and social and academic impairment were obtained from parents, while ratings of depressive s ymptoms and conflict with parents were obtained from youth. Among adolescents with ADHD, elevated depressive symptoms were associated with higher S...
Source: ADHD Attention Deficit and Hyperactivity Disorders - March 8, 2019 Category: Psychiatry Source Type: research

Attention deficit/hyperactivity disorder and future expectations in Russian adolescents
AbstractIn recent years, there has been an increasing focus on the role of future expectations —the extent to which a future outcome is deemed likely—in the health and well-being of adolescents, with research linking future expectations to outcomes such as an increased likelihood of engaging in risky health behaviors. As yet, however, there has been no research on future expectations and attention deficit/hyperactivity disorder (ADHD) in adolescence. To address this research gap, the current study examined the association between ADHD symptoms/possible ADHD status and future expectations in a school-based sample of ado...
Source: ADHD Attention Deficit and Hyperactivity Disorders - March 8, 2019 Category: Psychiatry Source Type: research

Correction to: Living “in the zone”: hyperfocus in adult ADHD
Authors have noted one error in the online published article, which they wish to clarify. The version of the Hobby Hyperfocus (HF) subscale that we administered to participants was unintentionally missing one answer option ( “once a week”). (Source: ADHD Attention Deficit and Hyperactivity Disorders)
Source: ADHD Attention Deficit and Hyperactivity Disorders - March 7, 2019 Category: Psychiatry Source Type: research

Reaction time variability and attention-deficit/hyperactivity disorder: is increased reaction time variability specific to attention-deficit/hyperactivity disorder? Testing predictions from the default-mode interference hypothesis
AbstractIncreased reaction time variability (RTV) is one of the most replicable behavioral correlates of attention-deficit/hyperactivity disorder (ADHD). However, this may not be specific to ADHD but a more general marker of psychopathology. Here we compare RT variability in individuals with ADHD and those with other childhood internalizing and externalizing conditions both in terms of standard (i.e., the standard deviation of reaction time) and alternative indices that capture low-frequency oscillatory patterns in RT variations over time thought to mark periodic lapses of attention in ADHD. A total of 667 participants (6 ...
Source: ADHD Attention Deficit and Hyperactivity Disorders - February 28, 2019 Category: Psychiatry Source Type: research

Prospective memory (partially) mediates the link between ADHD symptoms and procrastination
This study set out to bring the fields of prospective memory and procrastination research together and to explore possible relations between the two constructs in ADHD. Twenty-nine adults with ADHD and 24 healthy controls performed several l aboratory-based and real-life prospective memory tasks and filled in questionnaires measuring their symptom severity and procrastination behaviour. Overall, individuals’ with ADHD showed clear deficits in everyday prospective memory performance. Individuals with ADHD recalled and executed less of their own real-life intentions. Moreover, there were clear links between everyday prospe...
Source: ADHD Attention Deficit and Hyperactivity Disorders - February 28, 2019 Category: Psychiatry Source Type: research

Parent –clinician agreement in rating the presence and severity of attention-deficit/hyperactivity disorder symptoms
AbstractWe determined the validity of a parent-report questionnaire as a research tool for rating attention-deficit/hyperactivity disorder (ADHD) symptoms in children. Using Cohen ’s kappa and Pearson correlation, we examined the agreement between parent reports of ADHD symptoms (using the Swanson, Nolan and Pelham Questionnaire-IV; SNAP-IV) and clinical judgment (using a semi-structured parent interview). Also, we explored factors that may be associated with the level of a greement, using regression analyses. We found moderate levels of agreement for severity of overall ADHD (r = 0.43) and for hyperactive-impulsive ...
Source: ADHD Attention Deficit and Hyperactivity Disorders - February 28, 2019 Category: Psychiatry Source Type: research

ADHD: a hidden comorbidity in adult psychiatric patients
AbstractAdult attention-deficit/hyperactivity disorder (aADHD) has recently been better recognized and treated in many European countries. In spite of this development, aADHD still features as a “hidden” comorbidity, often not diagnosed even in patients under psychiatric treatment for other psychiatric disorders. The aim of this study was to establish the prevalence rates of unrecognized aADHD in academic centers providing regular psychiatric services in the Czech Republic and Hungary. In a population of psychiatric in-and outpatients, Adult ADHD Self-Report Scale was administered. All positively and about half of the ...
Source: ADHD Attention Deficit and Hyperactivity Disorders - February 28, 2019 Category: Psychiatry Source Type: research

Social-communicative and attention problems in infancy and toddlerhood as precursors of preschool autistic traits
AbstractThis longitudinal study focused on early behavioural problems and autistic traits. In a stratified, population-derived sample of 119 children, mothers reported through questionnaires on externalizing, internalizing, and social-communicative characteristics of their child in infancy (14  months) and toddlerhood (37 months), and on autistic traits at preschool age (4–5 years). Children with consistently normal behaviour from infancy to toddlerhood showed lower autistic traits at preschool age than children with deviant behaviour on one or both time points. High autistic traits at preschool age were predominantly...
Source: ADHD Attention Deficit and Hyperactivity Disorders - February 28, 2019 Category: Psychiatry Source Type: research

Apparent lack of practice effects in the Test of Variables of Attention (TOVA) in adult ADHD
AbstractThe test of variables of attention (TOVA) is a continuous performance test commonly used as an aid for diagnosis of ADHD and assessment of treatment response. It has been studied and standardized in both children and adults. As a repetitive measurement of treatment efficacy, used both in research and in the clinic, it ’s important to disprove a practice effect. A retrospective cohort analysis was done, using only the placebo-arm participants from two different randomized, multicenter, double-blind clinical trials on the efficacy of a non-stimulant (metadoxine-XR). In order to reveal the practice effects, only t h...
Source: ADHD Attention Deficit and Hyperactivity Disorders - February 28, 2019 Category: Psychiatry Source Type: research

Effect of disease-associated SLC9A9 mutations on protein –protein interaction networks: implications for molecular mechanisms for ADHD and autism
AbstractNa+/H+ Exchanger 9 (NHE9) is an endosomal membrane protein encoded by the Solute Carrier 9A, member 9 gene (SLC9A9).SLC9A9 has been implicated in attention deficit hyperactivity disorder (ADHD), autism spectrum disorders (ASDs), epilepsy, multiple sclerosis and cancers. To better understand the function of NHE9 and the effects of disease-associated variants on protein –protein interactions, we conducted a quantitative analysis of the NHE9 interactome using co-immunoprecipitation and isobaric labeling-based quantitative mass spectrometry. We identified 100 proteins that interact with NHE9. These proteins were enri...
Source: ADHD Attention Deficit and Hyperactivity Disorders - February 28, 2019 Category: Psychiatry Source Type: research

Family-based association study on functional α-synuclein polymorphisms in attention-deficit/hyperactivity disorder
In conclusion, we found in our pilot study a trend for an association of the rs356219 genotype inSNCA that may affect α-synuclein function and contribute to the aetiology of ADHD. In light of the small sample size of our study, the link between PD and ADHD through dopamine-related neurobiology warrants further investigations. Future studies onSNCA in large ADHD samples should focus on specified symptoms and traits, e.g. attentional capacities or emotional dysregulation. (Source: ADHD Attention Deficit and Hyperactivity Disorders)
Source: ADHD Attention Deficit and Hyperactivity Disorders - February 28, 2019 Category: Psychiatry Source Type: research

The role of the circadian system in the etiology and pathophysiology of ADHD: time to redefine ADHD?
AbstractAttention-deficit/hyperactivity disorder (ADHD) is highly associated with the delayed sleep phase disorder, a circadian rhythm sleep –wake disorder, which is prevalent in 73–78% of children and adults with ADHD. Besides the delayed sleep phase disorder, various other sleep disorders accompany ADHD, both in children and in adults. ADHD is either the cause or the consequence of sleep disturbances, or they may have a shared etio logical and genetic background. In this review, we present an overview of the current knowledge on the relationship between the circadian rhythm, sleep disorders, and ADHD. We also discuss...
Source: ADHD Attention Deficit and Hyperactivity Disorders - February 28, 2019 Category: Psychiatry Source Type: research

Sluggish cognitive tempo: longitudinal stability and validity
AbstractEmerging research has identified sluggish cognitive tempo (SCT) as a construct separate from ADHD predominately inattentive presentation. The present study explores the longitudinal stability of SCT over a period of 7  years, specifically the independent effects of SCT on behavioural and academic outcomes concurrently over a 3-year period. A sample of 639 twins, aged 6–12 years, participating in the Western Reserve Reading and Math Project (WRRMP) were assessed at seven annual home visits. The WRRMP sample is an unselected sample of twins representative of the general population of typically developing school-a...
Source: ADHD Attention Deficit and Hyperactivity Disorders - February 20, 2019 Category: Psychiatry Source Type: research

The importance of avoidant personality in social anxiety disorder with and without attention-deficit/hyperactivity disorder
AbstractIn the present study, our primary aim was to compare the generalized social anxiety (GSAD) patients with and without attention-deficit/hyperactivity disorder (ADHD) in terms of avoidant personality disorder (AVPD), and some clinical variables. We also investigated the relationship of AVPD and depression with ADHD and GSAD. We hypothesized that ADHD may be associated with AVPD in patients with GSAD. Seventy-six patients with GSAD were evaluated for depression, AVPD, and childhood and adulthood diagnoses of ADHD. The GSAD patients with (n = 34) and without adulthood ADHD (n = 30) were compared with respect to...
Source: ADHD Attention Deficit and Hyperactivity Disorders - February 14, 2019 Category: Psychiatry Source Type: research