Family-based association study on functional α-synuclein polymorphisms in attention-deficit/hyperactivity disorder

In conclusion, we found in our pilot study a trend for an association of the rs356219 genotype inSNCA that may affect α-synuclein function and contribute to the aetiology of ADHD. In light of the small sample size of our study, the link between PD and ADHD through dopamine-related neurobiology warrants further investigations. Future studies onSNCA in large ADHD samples should focus on specified symptoms and traits, e.g. attentional capacities or emotional dysregulation.
Source: ADHD Attention Deficit and Hyperactivity Disorders - Category: Psychiatry Source Type: research