Psychoneuroimmunoendocrinology: clinical implications
AbstractPsychoneuroimmunoendocrinology, which was first described in 1936, is the study of the interactions between the psyche, neural and endocrine functions and immune responses. The aim of psychoneuroimmunoendocrinology is to apply medical knowledge to the treatment of different allergic, immune, autoimmune, rheumatic, neoplastic, endocrine, cardiovascular and dental pathologies, among other disorders. Epigenetic factors and major stresses from different types of stimuli acting through distinct pathways and neurotransmitters are highly involved in altering the psychoneuroimmunoendocrine axis, resulting in the emergence ...
Source: World Allergy Organization Journal - June 6, 2017 Category: Allergy & Immunology Source Type: research
Knowledge and management of chronic spontaneous urticaria in Latin America: a cross-sectional study in Ecuador
ConclusionThis study shows that the knowledge of guideline recommendations in physicians who treat urticaria patients in Ecuador is low. The diagnostic workup and treatment of CsU patients are largely not in line with guideline recommendations in real life practice settings. We were able to compare results between German and Ecuadorian physicians and found that Ecuadorian physicians have lower awareness of the current guideline (33 vs 18%). Only one-third of physicians reported using regular doses of sgAHs as the first line treatment. Also, only 12.9% of physicians use sgAHs in higher doses and physicians still use fgAHs, ...
Source: World Allergy Organization Journal - May 23, 2017 Category: Allergy & Immunology Source Type: research
Why a registry of Chronic Urticaria (CUR) is needed
AbstractChronic urticaria (CU) has a major effect on patients ’ quality of life. While there have been progressive advances regarding its pathogenesis and treatment, much remains to be done.Registries of other chronic non-communicable diseases have shown many benefits, such as additional basic knowledge and management approaches to diabetes mellitus. Standards of care as well as diagnostic approaches can be elaborated and compared from different sites, using validated instruments. Registries in allergic diseases are also becoming well recognized, and the first registry on CU, accessible from SLaai ’s webpage, includes ...
Source: World Allergy Organization Journal - May 16, 2017 Category: Allergy & Immunology Source Type: research
In-flight allergic emergencies
AbstractAllergic and hypersensitivity reactions such as anaphylaxis and asthma exacerbations may occur during air travel. Although the exact incidence of in-flight asthma and allergic emergencies is not known, we have concerns that this subject has not received the attention it warrants. There is a need to provide passengers at risk and airlines with the necessary measures to prevent and manage these emergencies. A review of the epidemiology, management and approaches to prevention of allergic and asthma emergencies during air travel is presented with the goal of increasing awareness about these important, potentially prev...
Source: World Allergy Organization Journal - May 4, 2017 Category: Allergy & Immunology Source Type: research
Re “International survey on skin patch test procedures, attitudes and interpretation” L.K. Tanno et al., WAOJ (2016) 9:8
AbstractA previous survey on the practice of diagnostic patch testing among representatives of member societies of the World Allergy Organization (WAO) has, in some countries, not addressed those stakeholders actually involved in patch testing, mainly dermatologists. The need for further standardisation is acknowledged and has been addressed e.g. by publication of a patch test guideline by the European Society of Contact Dermatitis in October 2015. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - April 26, 2017 Category: Allergy & Immunology Source Type: research
Molecular fingerprinting of complex grass allergoids: size assessments reveal new insights in epitope repertoires and functional capacities
ConclusionThe structural and immunological changes which take place following the grass allergen modification process was further unravelled revealing distinct IgG immunological profiles. All epitopes were mapped on the solvent exposed area of Lol p 1 homology model accessible for IgG binding. One of the epitopes was identified as an ‘immunodominant’ Lol p 1 IgG-binding epitope (62-IFKDGRGCGSCFEIK-76) and classified as a novel epitope. The results from this study support the concept that modification allows shorter-course therapy options as a result of providing an IgG epitope repertoire important for efficacy. Additio...
Source: World Allergy Organization Journal - April 24, 2017 Category: Allergy & Immunology Source Type: research
International consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem
The objectives of this document are to highlight aspects of mite biology that are clinically relevant, to update the current knowledge on mite allergens, routes of sensitization, the genetics of IgE responses to mites, the epidemiologic aspects of mite hypersensitivity, the clinical pictures induced by mites, the diagnosis, specific immunotherapeutic approaches, and prevention. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - April 18, 2017 Category: Allergy & Immunology Source Type: research
Asthma control in primary care: the results of an observational cross-sectional study in Italy and Spain
ConclusionsThe results highlight the importance of routine longitudinal assessment of asthma patients in primary care and point to the need for an increased attention to asthma management by GPs. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - April 6, 2017 Category: Allergy & Immunology Source Type: research
Assessing eosinophilic cationic protein as a biomarker for monitoring patients with eosinophilic esophagitis treated with specific exclusion diets
ConclusionThe serial determination of ECP is useful when monitoring patients with EoE treated with specific diets. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - March 23, 2017 Category: Allergy & Immunology Source Type: research
Climate change, allergy and asthma, and the role of tropical forests
ConclusionDeforestation represents the second largest anthropogenic source of CO2 to the atmosphere, after fossil fuel combustion. There are many causes of deforestation, including socioeconomic and natural factors, such as clear-cutting for agriculture, ranching and development, unsustainable logging for timber, as well as droughts, fires and degradation due to climate change. About natural causes of forest degradation, in the context of the Amazon, the major agent of change in the forest ecosystem would most likely be decreased dry-season precipitation. Of the 23 global climate models employed by the Intergovernmental Pa...
Source: World Allergy Organization Journal - March 6, 2017 Category: Allergy & Immunology Source Type: research
Allergic diseases and asthma in pregnancy, a secondary publication
In conclusion, i) allergies in pregnancy should preferentially be diagnosed in vitro; ii) AIT may be continued, but not started, and symptomatic medications must be carefully selected; iii) management of asthma and allergic diseases is important during pregnancy for welfare of mother and child. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - March 1, 2017 Category: Allergy & Immunology Source Type: research
The impact on quality of life on families of children on an elimination diet for Non-immunoglobulin E mediated gastrointestinal food allergies
ConclusionsThis study found that parent QOL and family functioning was worse in those families who had a child on an elimination diet for non-IgE mediated allergies compared to those with sickle cell disease and intestinal failure, highlighting the impact this disease has on families. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - February 21, 2017 Category: Allergy & Immunology Source Type: research
Effect of adjuvanted and standard sublingual immunotherapy on respiratory function in pure rhinitis due to house dust mite over a 5-year period
ConclusionIn the real life setting, considering a 5-year period, aSLIT and sSLIT reduced the onset of new sensistizations and maintained intact the pulmonary function, as compared to patients receiving drug treatment alone. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - February 13, 2017 Category: Allergy & Immunology Source Type: research
An unusual cause of food-induced anaphylaxis in mothers
ConclusionsThe supplementation of GOS into milk and beverages in the Asian region should take into account the rare chance of allergenicity of GOS in the atopic population. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - February 9, 2017 Category: Allergy & Immunology Source Type: research
World Allergy Organization Journal: the Editors Look Back at 2016
(Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - January 22, 2017 Category: Allergy & Immunology Source Type: research
