The global impact of the DRACMA guidelines cow ’s milk allergy clinical practice
ConclusionsDRACMA reconciled international differences in the diagnosis and management of CMA. They promoted a cultural debate, improved clinician ’s knowledge of CMA, improved the quality of diagnosis and care, reduced inappropriate practices, fostered the efficient use of resources, empowered patients, and influenced some public policies. The accruing evidence on diagnosis and treatment of CMA necessitates their update in the near future. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - January 4, 2018 Category: Allergy & Immunology Source Type: research
Etiology of chronic urticaria: the Ecuadorian experience
ConclusionCSU is the most frequent subtype of CU. Modern non-sedating antihistamines in licensed doses are the drug of choice. Nevertheless, a great proportion of patients require the addition of another type of medication. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - January 3, 2018 Category: Allergy & Immunology Source Type: research
Gender effects in allergology – Secondary publications and update
(Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - December 28, 2017 Category: Allergy & Immunology Source Type: research
Gender-related aspects in occupational allergies – Secondary publication and update
AbstractFor years occupational allergies have been among the most frequently recorded occupational diseases, and both the skin as well as the respiratory tract may be affected. An estimated 9 to 15% of adult asthma is (partially) caused by work-related exposure. Gender-specific differences in exposure cause different risks in the workplace which affect the health of employees. This also applies to exposure and working conditions when handling sensitizing working substances. The presented gender-specific analysis of the German documentation of confirmed occupational respiratory allergic diseases and occupational skin diseas...
Source: World Allergy Organization Journal - December 27, 2017 Category: Allergy & Immunology Source Type: research
Adverse reactions to food: the female dominance – A secondary publication and update
AbstractGender-specific differences are evident in food intolerance and allergy. In this review, we will highlight and summarize the dissimilarities in prevalence of adverse food reactions, focusing on IgE-mediated food allergies and intolerances regarding frequency of symptoms and predisposing factors. After puberty, females suffer more frequently from food-related symptoms than males. Several factors may be responsible for this observation, for example hormonal effects, gender-specific behavior, perception of risk, or intake of medications. In this context, concrete studies related to adverse food reactions are still lac...
Source: World Allergy Organization Journal - December 27, 2017 Category: Allergy & Immunology Source Type: research
Sex hormone allergy: clinical aspects, causes and therapeutic strategies – Update and secondary publication
AbstractSex hormone allergy as a clinical syndrome has been known for almost a century. Due to the diversity of clinical presentation regarding symptoms and disease patterns, the optimal patient care represents an enormous interdisciplinary challenge. Frequently, hypersensitivity reactions affect more than one sex hormone and double positive tests for estrogen and progesterone have been described. Since the menstrual cycle dependent symptoms range from skin afflictions, gynecological problems to non-specific reactions, different pathophysiological mechanisms seem likely.Various desensitization protocols are described as ca...
Source: World Allergy Organization Journal - December 27, 2017 Category: Allergy & Immunology Source Type: research
Gender aspects and influence of hormones on bronchial asthma – Secondary publication and update
AbstractThere is good evidence for gender-specific differences in asthma regarding all affected areas, from intra- to extra-cellular mediators to the whole organ structure und functioning of the lung. These result from complex, in parts synergistic, in other parts opposing, effects — especially of female sex hormones, and rather protective effects of male hormones against asthma, which include effects on the cellular immune system. Additionally, there are gender differences of sociocultural origin, regarding presentation, doctor’s diagnosis and treatment of asthma sympt oms, as well as the undertaken coping strategi...
Source: World Allergy Organization Journal - December 27, 2017 Category: Allergy & Immunology Source Type: research
Gender aspects in allergies of pets – A secondary publication and update
AbstractAllergies need not only affect humans; this multifactorial and complex disease can also affect animals. Comparative allergology investigates the many similarities between the pathogenesis, clinics, diagnosis, and therapy of the disorders in humans and pet animals. In contrast to human allergy research, the veterinar y field lacks access to a central database, which means there are no cohort studies published. This limits not only the research on breed and regional differences in allergies, but also further studies on the impact of gender in allergies of domestic animals. Moreover, domestic cats, dogs and male h o...
Source: World Allergy Organization Journal - December 27, 2017 Category: Allergy & Immunology Source Type: research
Lactose intolerance and gastrointestinal cow ’s milk allergy in infants and children – common misconceptions revisited
AbstractLactose is the main carbohydrate in human and mammalian milk. Lactose requires enzymatic hydrolysis by lactase into D-glucose and D-galactose before it can be absorbed. Term infants express sufficient lactase to digest about one liter of breast milk daily. Physiological lactose malabsorption in infancy confers beneficial prebiotic effects, including the establishment of Bifidobacterium-rich fecal microbiota. In many populations, lactase levels decline after weaning (lactase non-persistence; LNP). LNP affects about 70% of the world ’s population and is the physiological basis for primary lactose intolerance (LI). ...
Source: World Allergy Organization Journal - December 12, 2017 Category: Allergy & Immunology Source Type: research
Proceedings of the 2017 WAO Symposium on Hot Topics in Allergy: Pediatric & amp; Regulatory Aspects
(Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - November 16, 2017 Category: Allergy & Immunology Source Type: research
Otitis media with effusion and atopy: is there a causal relationship?
AbstractOtitis Media with Effusion (OME) is an inflammatory condition of the middle ear cleft, acute or chronic, with collection of fluid in the middle ear with an intact tympanic membrane. It is a very common disease in childhood, the most frequent cause of hearing loss in childhood and often requiring surgery. OME is calledchronic when the fluid in the middle ear persists for more than three months or when the episodes recur six or more times in one year. The current article covers various aspects of OME including definition, epidemiology. Pathomechanisms, risk factors, role of allergy in OME, impact of upper airway dise...
Source: World Allergy Organization Journal - November 14, 2017 Category: Allergy & Immunology Source Type: research
Who has anaphylaxis in Brazil? Validation of a questionnaire for population studies
ConclusionThis instrument might be of particular value in places where researchers cannot access medical records to conduct similar epidemiological studies. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - November 8, 2017 Category: Allergy & Immunology Source Type: research
Prevalence of papular urticaria caused by flea bites and associated factors in children 1 –6 years of age in Bogotá, D.C.
ConclusionsA high prevalence of papular urticaria caused by flea bite was found in Bogot á D.C. The main factors associated with the disease might be modified with the implementation of prevention, control strategies in housing, educational institutions, and public transportation. (Source: World Allergy Organization Journal)
Source: World Allergy Organization Journal - November 7, 2017 Category: Allergy & Immunology Source Type: research
Psychological and lifestyle risk factors for asthma exacerbations and morbidity in children
AbstractAsthma is the most common childhood illness and disproportionately affects low-income, minority children who live in urban areas. A range of risk factors are associated with asthma morbidity and mortality, such as treatment non-adherence, exposure to environmental triggers, low-income households, exposure to chronic stress, child psychological problems, parental stress, family functioning, obesity, physical inactivity, and unhealthy diets. These risk factors often have complex interactions and inter-relationships. Comprehensive studies that explore the inter-relationships of these factors in accounting for asthma m...
Source: World Allergy Organization Journal - October 16, 2017 Category: Allergy & Immunology Source Type: research
