Seminars in Cutaneous Medicine and Surgery 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Common allergens present in personal care products: identification, diagnosis, and management.
Authors: Chou M, Mikhaylov D, Strugar TL
Abstract
The incidence of allergic contact dermatitis (ACD) reactions to personal care products has progressively increased, affecting women more so than men. Fragrances and preservatives are the major sensitizers behind cosmetic-induced ACD, due to their ubiquitous presence in these products, though emulsifiers, ultraviolet filters, and botanical allergens have been implicated as well. While patch testing is the standard for diagnosing ACD, many cosmetic-specific antigens are not currently included within the commercially available kits. Therefore, patch testing fo...
Source: Seminars in Cutaneous Medicine and Surgery - November 28, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Treatment of female pattern hair loss with combination therapy.
This article reviews common treatments of FPHL and their efficacy.
PMID: 30475928 [PubMed - in process] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - November 28, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Aesthetic considerations in female skin of color: what you need to know.
Authors: Henry M, Sadick N
Abstract
The world is flat when it comes to aesthetic treatments, meaning women and men from all walks of life, regardless of culture and ethnicity or even socioeconomic status, are seeking ways to improve their appearance, prevent aging, and rejuvenate their skin. Year after year, statistics show a steady increase in people of color undergoing aesthetic treatments, with neurotoxins, fillers, laser resurfacing, and body contouring being the most sought-after procedures. When treating this cohort of patients, however, dermatologists need to be sensitized to how a patient's ethnici...
Source: Seminars in Cutaneous Medicine and Surgery - November 28, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Updates on the understanding and treatment of cellulite.
Authors: Hogan S, Velez MW, Kaminer MS
Abstract
Cellulite is a common dermatologic condition and frequent cause of cosmetic concern among women. This paper aims to update what is known about the pathogenesis of cellulite and reviews targeted treatment modalities that address its underlying components of microvascular dysfunction, endocrine-mediated inflammation, and connective tissue fibrosclerosis.
PMID: 30475930 [PubMed - in process] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - November 28, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Aesthetic Consideration in Women's Health, Introduction.
Authors: Bonati LM, Sadeghpour M, Quatrano NA
Abstract
PMID: 30475931 [PubMed - in process] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - November 28, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Vaginal wellness: whose turf is it?
Authors: Lee MC
Abstract
Dermatologists were the pioneers in the development of laser technology and have the most experience using these lasers to treat the external genitalia for many cutaneous disorders. Dermatologists who have experience and expertise using lasers and devices, are already using them to treat the external genitalia, and are comfortable performing female gynecologic exams may want to explore the wide range of options that are available to treat the functional and aesthetic needs of the female population. Dermatologists should work with obstetricians and gynecologists to ensure that patie...
Source: Seminars in Cutaneous Medicine and Surgery - November 28, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
The vaginal wellness consultation for treatment with energy-based devices.
Authors: Miller MD
Abstract
PMID: 30475933 [PubMed - in process] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - November 28, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Vaginal rejuvenation: whose turf?
Authors: Schilling L, Saedi N
Abstract
Many medical conditions can cross over the territories of various specialties. These conditions may benefit from, or even require, a multidisciplinary approach. While ideally this leads to a collaborative and coveted patient-centered care model, it can also give rise to competitive turf wars. A popular topic that has entered the turf wars is vaginal rejuvenation. Vaginal rejuvenation through light- and energy-based devices is a rapidly expanding field, quickly gaining the attention of dermatologists and gynecologists alike. Dermatology has the most experience and expe...
Source: Seminars in Cutaneous Medicine and Surgery - November 28, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Melasma: update on management.
Authors: Suggs AK, Hamill SS, Friedman PM
Abstract
Melasma is a common, acquired, chronic cutaneous pigment disorder that is often difficult to treat and has a high recurrence rate. The goal of a melasma treatment regimen is to decrease pigment production and increase elimination. Topical tyrosinase inhibitors block melanin synthesis and thereby reduce pigment production. Peels and laserand light-based devices increase melanin elimination. A multimodality treatment approach targeting both pigment production and elimination is necessary to achieve equilibrium and disease remission. Maintenance treatments ar...
Source: Seminars in Cutaneous Medicine and Surgery - November 28, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Using targeted therapies for inflammatory dermatoses.
Authors: Sobell JM
PMID: 30215628 [PubMed - in process] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - September 16, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
TNF inhibitors for psoriasis.
Authors: Chima M, Lebwohl M
Abstract
Tumor necrosis factor (TNF)-α has been identified as a key cytokine mediating cutaneous inflammation in the pathogenesis of psoriasis. The TNF inhibitors (TNFi's) infliximab, adalimumab, and etanercept are efficacious, Food and Drug Administration-approved medications for the treatment of moderate-to-severe plaque psoriasis. Each drug has a unique pharmacological profile that can have therapeutic implications when choosing a particular TNFi for a patient. An understanding of these idiosyncrasies can help guide therapeutic decisions for patients with psoriasis that also...
Source: Seminars in Cutaneous Medicine and Surgery - September 16, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Ustekinumab for the treatment of psoriasis: an evidence update.
Authors: Yiu ZZ, Warren RB
Abstract
Ustekinumab is an interleukin-12/23 inhibitor used for the treatment of moderate-to-severe psoriasis. Here, we review new evidence since ustekinumab was licensed for relative efficacy in comparison with other biologic therapies from head-to-head randomized controlled trials and network meta-analyses for the treatment of psoriasis. We also review observational data emerging from psoriasis registries reporting the effectiveness and safety of ustekinumab. Overall, new evidence suggests that ustekinumab has a favorable balance between efficacy/effectiveness, safety, and tole...
Source: Seminars in Cutaneous Medicine and Surgery - September 16, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
IL-17 inhibitors for psoriasis.
Authors: Paek SY, Frieder J, Kivelevitch D, Menter MA
Abstract
The role of the Th17/interleukin (IL)-23 pathway has been well elucidated in psoriasis. The IL-17 family includes 6 cytokines: IL-17A, IL-17B, IL-17C, IL-17D, IL-17E, and IL-17F. Two monoclonal antibodies targeting IL-17A (secukinumab, ixekizumab) and one antibody against the IL-17 receptor (brodalumab) have been approved for the treatment of moderate-to-severe plaque psoriasis. Clinical efficacy, safety, and tolerability of each agent is reviewed.
PMID: 30215631 [PubMed - in process] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - September 16, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
IL-23 inhibitors for moderate-to-severe psoriasis.
Authors: Ibler E, Gordon KB
Abstract
Since the identification of high levels of interleukin 23 (IL- 23) in psoriasis lesional skin, as well as finding that IL-23 was the most important source of the p40 subunit shared by IL-12 and IL-23, significant effort has been made in identifying potential new drugs that specifically block the unique IL-23 p19 subunit. At this time, 2 inhibitors of IL-23 p19 have been approved by the United States Food and Drug Administration, guselkumab and tildrakizumab. Two other agents, risankizumab and mirikizumab, have completed phase 3 and phase 2 of development, respectively. ...
Source: Seminars in Cutaneous Medicine and Surgery - September 16, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Oral small molecules for psoriasis.
Authors: Singh S, Armstrong AW
Abstract
Psoriasis is chronic inflammatory skin condition that imposes a significant physical and psychosocial burden on patients. Moderate to severe psoriasis often requires systemic treatments, including oral systemic therapies and biologics. An addition to the treatment repository for psoriasis is oral small molecules, which include apremilast, tofacitinib, and ponesimod. Of these 3 medications, only apremilast is currently approved for the treatment of psoriasis. Long-term safety data for apremilast suggest that it has a tolerable safety profile and leads to significant i...
Source: Seminars in Cutaneous Medicine and Surgery - September 16, 2018 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
