Seminars in Cutaneous Medicine and Surgery 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.The Changing Paradigm of Atopic Dermatitis Therapy.
Authors: Friedlander SF, Simpson EL, Irvine AD, Eichenfield LF
Abstract
The pathophysiology of atopic dermatitis (AD) is complex, and future treatment options will likely be incorporated in a multimodal approach to management. The new, directed therapies that have been developed will likely be used in conjunction with concomitant continuous or intermittent use of standard therapies; the goal is to optimize therapeutic outcomes while minimizing adverse impacts on safety and cost. Current data regarding disease course and expression throughout life suggest that treatment strategies also will need to be adjus...
Source: Seminars in Cutaneous Medicine and Surgery - August 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Translating the Science of Psoriasis.
Authors: Gordon KB
Abstract
Knowledge about the pathophysiology of psoriasis has evolved substantially in recent years, since the identification of the T helper 17 (Th17) cells. Cytokines produced by these cells appear to play major roles in psoriatic inflammation. The cytokine interleukin (IL)-23 appears to promote regulatory T cells to differentiate into Th17 cells. Available and investigational therapies act on targets within these pathways. Semin Cutan Med Surg 35(supp4):S64.
PMID: 27526392 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - August 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Therapeutic Approach to Acne and Rosacea, Introduction.
Authors: Graber EM
Abstract
Acne has been written about since ancient Greek times and was a recognized entity even during Cleopatra's reign. Today, acne is pervasive in most cultures and is the number two reason why patients visit a dermatologist in the United States. It is the eighth most common disease worldwide. Despite the longstanding awareness of acne and its prevalence, no perfect treatment yet exists.
PMID: 27416307 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - July 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Topical retinoids for acne.
Authors: Yeh L, Bonati LM, Silverberg NB
Abstract
Topical retinoids are currently approved by the US Food and Drug Administration for the treatment of acne vulgaris in nonpregnant, nonlactating patients 12 years of age and older. Their efficacy, safety, and tolerability are well documented for inflammatory and noninflammatory acne with studies repeatedly demonstrating a decrease in the number of lesions, significant improvement in acne severity, improvement in the cosmetic appearance of acne, and the prevention of acne lesions through microcomedone formation. There is some variability between prescription ...
Source: Seminars in Cutaneous Medicine and Surgery - July 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Topical and oral antibiotics for acne vulgaris.
Authors: Del Rosso JQ
Abstract
Antibiotics, both oral and topical, have been an integral component of the management of acne vulgaris (AV) for approximately 6 decades. Originally thought to be effective for AV due to their ability to inhibit proliferation of Propionibacterium acnes, it is now believed that at least some antibiotics also exert anti-inflammatory effects that provide additional therapeutic benefit. To add, an increase in strains of P acnes and other exposed bacteria that are less sensitive to antibiotics used to treat AV have emerged, with resistance directly correlated geographically with th...
Source: Seminars in Cutaneous Medicine and Surgery - July 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Antibiotic-resistant acne: getting under the skin.
Authors: Sinha M, Sadhasivam S, Bhattacharyya A, Jain S, Ghosh S, Arndt KA, Dover JS, Sengupta S
Abstract
Propionibacterium acnes is a key pathogenic factor in the development of acne. Antibiotics are the first choice of treatment for mild-to-moderate, mixed, papular/pustular, and moderate nodular acne, and an alternative choice in severe, nodular/conglobate acne. The emergence of resistance to the currently available antibiotics poses a serious set-back to this algorithm, and the reduced arsenal can diminish efficacy of treatment. This emerging situation should catalyze innovations in dermatology; for exa...
Source: Seminars in Cutaneous Medicine and Surgery - July 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
The use of hormonal agents in the treatment of acne.
Authors: Hassoun LA, Chahal DS, Sivamani RK, Larsen LN
Abstract
Hormones and androgens play an important role in the pathogenesis of acne. Multiple hormonal modulators are now available for the treatment of acne. The efficacies and side effects of currently available hormonal agents are reviewed here including the use of oral contraceptives, spironolactone, flutamide, cyproterone acetate, finasteride, and cortexolone 17α-propionate. Hormonal therapies are an efficacious treatment option for acne among females. With the growing need to reduce antibiotic exposures, hormonal therapies should be more widely s...
Source: Seminars in Cutaneous Medicine and Surgery - July 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Topical and oral therapeutic approach to rosacea.
Authors: Helfrich YR, Maier LM
Abstract
Rosacea is an inflammatory condition of the skin, primarily affecting the central convexities of the face. Various topical and oral therapeutic approaches exist. Most have been developed to treat the papulopustular subtype of rosacea; however, other approaches can be used to treat the erythematotelangiectatic, ocular, and phymatous subtypes. This review provides a summary of available topical and oral approaches for the treatment of rosacea.
PMID: 27416312 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - July 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Isotretinoin for acne and rosacea.
Authors: Watson KD, Miest RY, Tollefson MM
Abstract
Isotretinoin is a revolutionary medicine for the treatment of acne vulgaris, with new studies showing evidence of excellent clinical outcomes in treating rosacea. After 30 years of clinical experience, new insights are being gained into dosing strategies, recurrence prevention, and dose-related side effects. Previous controversial associations with inflammatory bowel diseases and mood disorders have hampered the use of this medication in some clinical situations, with new evidence disproving these claims. The teratogenicity of this medication mandates iPL...
Source: Seminars in Cutaneous Medicine and Surgery - July 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Over-the-counter treatments for acne and rosacea.
Authors: Rosamilia LL
Abstract
Acne and rosacea are common inflammatory processes historically classified in the same disease category, but evolving understanding of their disparate pathophysiology and exacerbating factors have generated an enormous armamentarium of therapeutic possibilities. Patients seek over-the-counter therapies first when managing cutaneous disease; therefore, this review defines ingredients considered to be effective over-the-counter acne and rosacea products, their mechanisms, and safe formulations, including botanical components, oral supplements, and other anecdotal options in thi...
Source: Seminars in Cutaneous Medicine and Surgery - July 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Physical modalities for treating acne and rosacea.
Authors: Jalian HR, Levin Y, Wanner M
Abstract
Physical modalities provide an important adjunct to medical treatment of acne and rosacea. In patients who cannot tolerate or fail medical treatments, physical modalities offer an alternative approach. For cases of acne scarring, phymatous changes of rosacea, and rosacea-associated telangiectasia, physical modalities such as laser and light treatments represent the treatment of choice. We will review the use of laser and light treatments, photodynamic therapy, and other physical modalities such as targeted therapies for the treatment of acne and rosacea.
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Source: Seminars in Cutaneous Medicine and Surgery - July 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
What's new in acne and rosacea?
Authors: Keri J
Abstract
Acne and rosacea are common conditions seen every day by dermatologists. This review will discuss the most recent therapeutic options for patients with these conditions. Specifically, for acne, there will be a discussion of the use of isotretinoin at higher cumulative doses as well as a new formulation of isotretinoin, isotretinoin-lidose. Adult women with acne represent a growing population of patients who present for treatment of acne; the use of hormonal therapies as well as topical dapsone gel will be reviewed for these patients. For rosacea patients, the new topical agents - b...
Source: Seminars in Cutaneous Medicine and Surgery - July 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
40th Annual Hawaii Dermatology Serminar. Scientific Abstracts. Big Island, Hawaii, February 14-19, 2016.
Authors:
PMID: 27347676 [PubMed - in process] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - June 29, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Using Topical Antifungal Medications: Instructions for patients.
Authors: Stein Gold LF, Rosen T
PMID: 27135113 [PubMed - in process] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - May 3, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Introduction.
Authors: Stein Gold LF, Rosen T
PMID: 27096143 [PubMed - in process] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - April 21, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
