Seminars in Cutaneous Medicine and Surgery 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Fillers: What's Here and What's Ahead.
Authors: Solish N
Abstract
Soft tissue augmentation products (or fillers) are used for the correction of age-related changes in areas of the face. The most common filler material is hyaluronic acid, which is synthetically cross-linked. These materials are generally safe, but some side effects do occur. New fillers are expected to be approved in the United States in the near future. Semin Cutan Med Surg 35(supp6):S117-119.
PMID: 27537207 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - August 19, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Facial Dermatitis and Rosacea.
Authors: Fowler JF
Abstract
Rosacea is a chronic skin disorder associated with flushing, erythema, dryness, burning and stinging, and inflammatory papules and pustules. New treatments available or in development target the inflammatory and erythematous components of the disease. These agents include the selective α2 receptor agonist brimonidine, the topical agents ivermectin cream 1% and azelaic acid foam 15%, and use of tetracyclinetype antibiotics, which affect the cathelicidin pathway. Semin Cutan Med Surg 35(supp6):S107-S109.
PMID: 27537212 [PubMed - as supplied by publisher] (Source: Seminars...
Source: Seminars in Cutaneous Medicine and Surgery - August 19, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
The Aging Face: Global Approach With Fillers and Neuromodulators.
Authors: Solish N
Abstract
The goal of treating the aging face is to restore facial balance and modify shadows. A facial evaluation should focus on areas of volume loss and opportunities to use neuromodulators (eg, botulinum toxin A) and the use of fillers. A thorough understanding of facial anatomy, including muscles, nerves, bone, and fat pads, is essential for effective and safe treatment. Semin Cutan Med Surg 35(supp6):S120-S121.
PMID: 27537350 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - August 19, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Facial Rejuvenation: 40th Anniversary Review.
Authors: Zachary CB
Abstract
For decades, devices and peels have been used for facial rejuvenation and the treatment of skin damage. In recent years, new laser systems have been developed, including fractionated ablative and non-ablative lasers which, while not as effective as the traditional laser resurfacing, can provide nice results with reduced side effects. While fractionated hybrid systems, picosecond lasers, and daylight photodynamic therapy have all been rolled out for clinicians to assess their efficacy, future technology, including TRASER (total reflection amplification of spontaneous emission of...
Source: Seminars in Cutaneous Medicine and Surgery - August 19, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Tinea and Onychomycosis.
Authors: Rosen T
Abstract
Onychomycosis and tinea pedis are common fungal infections affecting the nails and feet, respectively. Two newly approved topical agents for onychomycosis are efinaconazole and tavaborole, both of which have demonstrated respectable cure rates in clinical studies. For tinea pedis, naftifine 2% and luliconazole 1% are new agents, both administered for relatively short courses, that may foster greater adherence Semin Cutan Med Surg 35(supp6):S110-S113.
PMID: 27537822 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - August 19, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Introduction.
Authors: Fowler JF, Zachary CB
PMID: 27537832 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - August 19, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Acne: What's New.
Authors: Stein Gold LF
Abstract
Acne vulgaris is one of the most prevalent skin conditions. Antibiotics, when considered, are most effective in combination with other therapies, and limited evidence suggests that submicrobial doses of antibiotics may improve acne without increasing the risk for antibiotic resistance. A small but significant risk for inflammatory bowel disease has also been identified in children treated with multiple courses of antibiotics. New topical agents are expanding therapeutic options for acne. Semin Cutan Med Surg 35(supp6):S114-S116.
PMID: 27538054 [PubMed - as supplied b...
Source: Seminars in Cutaneous Medicine and Surgery - August 19, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
New Therapies for Psoriasis.
This article reviews the data documenting the efficacy and safety of three types of biologics. Semin Cutan Med Surg 35(supp4):S74-S77.
PMID: 27525355 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - August 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Update on Epidemiology, Diagnosis, and Disease Course of Atopic Dermatitis.
Authors: Simpson EL, Irvine AD, Eichenfield LF, Friedlander SF
Abstract
Studies of the prevalence of atopic dermatitis (AD) have provided insights into associated environmental risk factors, demonstrating the complex interactions between the presence of filaggrin (FLG) gene defects and environment. Among other important findings is that elevated transepidermal water loss (TEWL) in newborns is a strong predictor of AD, regardless of FLG status. Recently recognized predictors of disease course and severity include onset of AD signs and symptoms before 12 months of age and the presence of an FLG mutation and ...
Source: Seminars in Cutaneous Medicine and Surgery - August 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Why Biologic Therapies Sometimes Lose Efficacy.
Authors: Strober BE
Abstract
Biologic therapies for psoriasis are associated with loss of response over time. Immunogenicity, suboptimal dosing, low serum drug levels, and intermittent or episodic therapy have been documented as explanations for this phenomenon. Use of an immunomodulatory agent can reduce the risk of immunogenicity and improve clinical response. Semin Cutan Med Surg 35(supp4):S78-S80.
PMID: 27525443 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - August 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Review of Critical Issues in the Pathogenesis of Atopic Dermatitis.
Authors: Irvine AD, Eichenfield LF, Friedlander SF, Simpson EL
Abstract
About a decade age, loss-of-function mutations in the filaggrin molecule were first implicated in the pathogenesis of ichthyosis vulgaris and, subsequently, of atopic dermatitis and other atopic diseases. Since then, intensive study of the role of filaggrin null mutations have led to other milestones in understanding the pathologic pathways in these diseases, including the initiation, maintenance, and promotion of the disease processes. The result has been new and emerging clinical and pharmacologic strategies for early identification ...
Source: Seminars in Cutaneous Medicine and Surgery - August 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Small Molecules for Psoriasis.
Authors: Leonardi CL
Abstract
Acitretin is an older, oral, non-immunosuppressive medication for the treatment of psoriasis. Tofacitinib is an oral Janus kinase inhibitor that has been studied for use in psoriasis. Each offers efficacy in certain settings and patient types but carries substantial safety risks. Semin Cutan Med Surg 35(supp4):S65-S66.
PMID: 27525564 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - August 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Assessing the New and Emerging Treatments for Atopic Dermatitis.
Authors: Eichenfield LF, Friedlander SF, Simpson EL, Irvine AD
Abstract
The newer and emerging treatments for atopic dermatitis (AD) focus on blockade of inflammatory cytokines, especially those that derive from T helper cell type 2 (TH2) and are associated with a pathway of immunoglobulin E (IgE) sensitization. Among the proinflammatory cytokines that have been identified as promising therapeutic targets are chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2), IgE, thymic stromal lymphopoietin (TSLP), and several monoclonal antibodies that block key cytokine pathways in the innate ...
Source: Seminars in Cutaneous Medicine and Surgery - August 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Update on TNF Inhibitors.
Authors: Kerdel FA
Abstract
The introduction of tumor necrosis factor (TNF)-α inhibitors dramatically improved the management of psoriasis. Some newer or investigational biologics with different mechanisms of action have demonstrated noninferiority or superiority to etanercept, the first self-injectable anti-TNF-α agent to become available in the United States. Nonetheless, TNF-α inhibitors are likely to remain a mainstay of therapy for many years. Semin Cutan Med Surg 35(supp4):S67-S70.
PMID: 27526035 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - August 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
Introduction.
Authors: Eichenfield LF
PMID: 27526228 [PubMed - as supplied by publisher] (Source: Seminars in Cutaneous Medicine and Surgery)
Source: Seminars in Cutaneous Medicine and Surgery - August 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research
