Why Biologic Therapies Sometimes Lose Efficacy.

Why Biologic Therapies Sometimes Lose Efficacy.
Semin Cutan Med Surg. 2016 Jun;35(4S):S64
Authors: Strober BE
Abstract
Biologic therapies for psoriasis are associated with loss of response over time. Immunogenicity, suboptimal dosing, low serum drug levels, and intermittent or episodic therapy have been documented as explanations for this phenomenon. Use of an immunomodulatory agent can reduce the risk of immunogenicity and improve clinical response. Semin Cutan Med Surg 35(supp4):S78-S80.
PMID: 27525443 [PubMed - as supplied by publisher]

Source: Seminars in Cutaneous Medicine and Surgery - August 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research