Antibiotic-resistant acne: getting under the skin.

Antibiotic-resistant acne: getting under the skin.
Semin Cutan Med Surg. 2016 Jun;35(2):62-67
Authors: Sinha M, Sadhasivam S, Bhattacharyya A, Jain S, Ghosh S, Arndt KA, Dover JS, Sengupta S
Abstract
Propionibacterium acnes is a key pathogenic factor in the development of acne. Antibiotics are the first choice of treatment for mild-to-moderate, mixed, papular/pustular, and moderate nodular acne, and an alternative choice in severe, nodular/conglobate acne. The emergence of resistance to the currently available antibiotics poses a serious set-back to this algorithm, and the reduced arsenal can diminish efficacy of treatment. This emerging situation should catalyze innovations in dermatology; for example, newer drugs and technologies such as next-generation antibiotics with excellent potency and low propensity to develop resistance, rapid diagnostic platforms to select responders and nonresponders, and delivery technologies that target the bacteria. Such innovations can dramatically expand the arsenal for dermatologists in the management of acne.
PMID: 27416310 [PubMed - as supplied by publisher]

Source: Seminars in Cutaneous Medicine and Surgery - July 16, 2016 Category: Dermatology Tags: Semin Cutan Med Surg Source Type: research