Different P50 sensory gating measures reflect different cognitive dysfunctions in schizophrenia
Publication date: Available online 9 September 2015 Source:Schizophrenia Research: Cognition Author(s): Atsuhito Toyomaki, Naoki Hashimoto, Yuki Kako, Yoshiro Tomimatsu, Tsukasa Koyama, Ichiro Kusumi The P50 is an early component of auditory evoked potentials and a measure of sensory gating deficits. This evoked potential component is thought to be an important endophenotype candidate for schizophrenia. Recent research suggests that instead of the P50 ratio, S1 and S2 amplitudes should be evaluated for sensory gating. However, no studies have focused on the relationship between cognitive dysfunction and P50...
Source: Schizophrenia Research: Cognition - September 9, 2015 Category: Psychiatry Source Type: research
Factors predicting work outcome in Japanese patients with schizophrenia: role of multiple functioning levels
Publication date: Available online 9 September 2015 Source:Schizophrenia Research: Cognition Author(s): Chika Sumiyoshi, Philip D. Harvey, Manabu Takaki, Yuko Okahisa, Taku Sato, Ichiro Sora, Keith H. Nuechterlein, Kenneth L. Subotnik, Tomiki Sumiyoshi Functional outcomes in individuals with schizophrenia suggest recovery of cognitive, everyday, and social functioning. Specifically improvement of work status is considered to be most important for their independent living and self-efficacy. The main purposes of the present study were 1) to identify which outcome factors predict occupational functioning...
Source: Schizophrenia Research: Cognition - September 9, 2015 Category: Psychiatry Source Type: research
Poor premorbid school performance, but not severity of illness, predicts cognitive decline in schizophrenia in midlife
Publication date: Available online 9 September 2015 Source:Schizophrenia Research: Cognition Author(s): Irina Rannikko, Graham K. Murray, Pauliina Juola, Henri Salo, Marianne Haapea, Jouko Miettunen, Juha Veijola, Jennifer H. Barnett, Anja P. Husa, Peter B. Jones, Marjo-Riitta Järvelin, Matti Isohanni, Erika Jääskeläinen Neurocognitive dysfunction is common in schizophrenia but its course and determinants remain uncertain. Our aim was to analyse if premorbid school performance and the severity of illness and functioning predict change in cognition in schizophrenia in a general population s...
Source: Schizophrenia Research: Cognition - September 9, 2015 Category: Psychiatry Source Type: research
Recuperación Clinica Pero No Cognitiva En Esquizofrenia A Traves De La Experiencia Del Cine De Ficcion
Publication date: Available online 1 August 2015 Source:Schizophrenia Research: Cognition Author(s): J. Peña, P. Sánchez, E. Elizagárate, N. Ibarretxe-Bilbao, J. Ezcurra, L. Caballero, M. Margariños, I. García Del Castillo, M. Gutiérrez, N. Ojeda Introducción Una de las críticas que se hace a las técnicas de la rehabilitación es la limitada generalización a la vida cotidiana del paciente. El cine se ha empleado como herramienta de rehabilitación psiquiátrica en el pasado con el objetivo principal de facilitar el entrenamiento en habilidades sociales y de comunicación. En este estudio n...
Source: Schizophrenia Research: Cognition - August 2, 2015 Category: Psychiatry Source Type: research
El procesamiento temporal en la esquizofrenia: Revisión
Publication date: Available online 29 July 2015 Source:Schizophrenia Research: Cognition Author(s): Irene Alústiza, Nuria Pujol, Patricio Molero, Felipe Ortuño We review the main contributions of the cognitive neuroscience literature in the field of time processing in schizophrenia. First, we summarize the theoretical concepts and terminology related to time and time estimation as well as the characterization of this deficit in the illness. Secondly, we deeply review the neuroanatomical basis of this deficit and its interaction with other cognitive processes and clinical symptoms. Thirdly, we specifically zoo...
Source: Schizophrenia Research: Cognition - July 30, 2015 Category: Psychiatry Source Type: research
Búsqueda De Nuevos Biomarcadores De La Cognición En Esquizofrenia
Publication date: Available online 26 July 2015 Source:Schizophrenia Research: Cognition Author(s): R. Penadés, C. García-Rizo, C. Garcia-Rizo, M. Bioque, A. González-Rodríguez, B. Cabrera, G. Mezquida, M. Bernardo La búsqueda de biomarcadores en la cognición ha centrado una gran parte de las investigaciones en pacientes con esquizofrenia. La literatura científica es heterogénea y son escasos los estudios disponibles que permitan establecer un modelo integrador de la etiopatogenia y respuesta terapéutica basada en estos marcadores. En el presente trabajo nos proponemos revisar tres aspectos fun...
Source: Schizophrenia Research: Cognition - July 26, 2015 Category: Psychiatry Source Type: research
Influencia del polimorfismo Val158Met COMT en el procesamiento de contexto en pacientes del espectro de la esquizofrenia y en sus familiares
Conclusiones: Los déficits de procesamiento de contexto en la esquizofrenia y en sus familiares están influenciados por el polimorfismo funcional Val158Met COMT, probablemente como una consecuencia de una menor disponibilidad de dopamina en el córtex prefrontal. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - July 8, 2015 Category: Psychiatry Source Type: research
Does chronic nicotine consumption influence visual backward masking in schizophrenia and schizotypy?
Publication date: June 2015 Source:Schizophrenia Research: Cognition, Volume 2, Issue 2 Author(s): Albulena Shaqiri , Julie Willemin , Guillaume Sierro , Maya Roinishvili , Luisa Iannantuoni , Linda Rürup , Eka Chkonia , Michael H. Herzog , Christine Mohr Nicotine consumption is higher for people within the schizophrenia spectrum compared to controls. This observation supports the self-medication hypothesis, that nicotine relieves symptoms in, for example, schizophrenia patients. We tested whether performance in an endophenotype of schizophrenia (visual backward masking, VBM) is modulated by nicotine consumpt...
Source: Schizophrenia Research: Cognition - June 20, 2015 Category: Psychiatry Source Type: research
The concept of schizotypy — A computational anatomy perspective
Publication date: June 2015 Source:Schizophrenia Research: Cognition, Volume 2, Issue 2 Author(s): C. Modenato , B. Draganski Despite major progress in diagnostic accuracy and symptomatic treatment of mental disorders, there is an ongoing debate about their classification aiming to follow current advances in neurobiology. The main goal of this review is to provide a comprehensive summary of the put forward schizotypy concept that follows the needs for objective assessment of schizophrenia-like personality traits in the general population. We focus on major achievements in the field from the perspective of magnetic re...
Source: Schizophrenia Research: Cognition - June 20, 2015 Category: Psychiatry Source Type: research
A vision science perspective on schizophrenia
Publication date: June 2015 Source:Schizophrenia Research: Cognition, Volume 2, Issue 2 Author(s): Steven M. Silverstein , Judy L. Thompson (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - June 20, 2015 Category: Psychiatry Source Type: research
Insight and subjective measures of quality of life in chronic schizophrenia
The objective of this study was to examine factors that might influence insight (as assessed by the Insight and Treatment Attitudes Questionnaire [ITAQ] or PANSS item G12) and subjective quality-of-life (as assessed by Lehman QoL Interview [LQOLI]), using the large National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) dataset. Uncooperativeness was assessed by PANSS item G8 (“Uncooperativeness”). In the analysis, we found significant moderating effects for insight on the relationships of subjective life satisfaction assessment to symptom severity (as assessed by CGI-S s...
Source: Schizophrenia Research: Cognition - June 9, 2015 Category: Psychiatry Source Type: research
Schizophrenia patients and 22q11.2 deletion syndrome adolescents at risk express the same deviant patterns of resting state EEG microstates: A candidate endophenotype of schizophrenia
Publication date: Available online 27 May 2015 Source:Schizophrenia Research: Cognition Author(s): Miralena I. Tomescu , Tonia A. Rihs , Maya Roinishvili , F. Isik Karahanoglu , Maude Schneider , Sarah Menghetti , Dimitri Van De Ville , Andreas Brand , Eka Chkonia , Stephan Eliez , Michael H. Herzog , Christoph M. Michel , Céline Cappe Schizophrenia is a complex psychiatric disorder and many of the factors contributing to its pathogenesis are poorly understood. In addition, identifying reliable neurophysiological markers would improve diagnosis and early identification of this disease. The 22q11.2 deletio...
Source: Schizophrenia Research: Cognition - May 27, 2015 Category: Psychiatry Source Type: research
Investigating vision in schizophrenia through responses to humorous stimuli
Publication date: Available online 27 May 2015 Source:Schizophrenia Research: Cognition Author(s): Wolfgang Tschacher , Ruth Genner , Jana Bryjová , Elisabeth Schaller , Andrea C. Samson The visual environment of humans contains abundant ambiguity and fragmentary information. Therefore, an early step of vision must disambiguate the incessant stream of information. Humorous stimuli produce a situation that is strikingly analogous to this process: Funniness is associated with the incongruity contained in a joke, pun, or cartoon. Like in vision in general, appreciating a visual pun as funny necessitates disambiguati...
Source: Schizophrenia Research: Cognition - May 27, 2015 Category: Psychiatry Source Type: research
Intermittent degradation and schizotypy
Publication date: Available online 21 May 2015 Source:Schizophrenia Research: Cognition Author(s): Matthew W. Roché , Steven M. Silverstein , Mark F. Lenzenweger Intermittent degradation refers to transient detrimental disruptions in task performance. This phenomenon has been repeatedly observed in the performance data of patients with schizophrenia. Whether intermittent degradation is a feature of the liability for schizophrenia (i.e., schizotypy) is an open question. Further, the specificity of intermittent degradation to schizotypy has yet to be investigated. To address these questions, 92 undergraduate particip...
Source: Schizophrenia Research: Cognition - May 22, 2015 Category: Psychiatry Source Type: research
Meeting overview: Sensory perception and schizophrenia, Lausanne, Switzerland June 31–July 1, 2014
This article summarizes a conference on visual processing dysfunction in schizophrenia held in Lausanne, Switzerland from June 30 to July 1, 2014 and introduces this special issue. Speakers focused on multiple aspects of visual dysfunction in schizophrenia using behavioral, neurophysiological and fMRI-based approaches. Four main themes emerged. First was a focus on response disturbances within the early visual system, using paradigms such as sensory EEG and MEG-based responses. Second, behavioral deficits were noted in processing related to local interaction within visual regions, using paradigms such as Vernier acuity or ...
Source: Schizophrenia Research: Cognition - May 22, 2015 Category: Psychiatry Source Type: research
